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The use of starch microspheres and nanoparticles in pharmaceutical applications

Fureby, Anna Millqvist LU ; Gidlöf, Zandra LU and Wahlgren, Marie LU orcid (2024) p.487-501
Abstract

Starch is generally regarded as safe for human consumption and has therefore attracted interest for several applications as medicinal products. This chapter focuses specifically on starch microspheres as carriers for drug delivery and as a medical device for, for example, vascular occlusion. Several methods for the preparation of starch microspheres by chemical or physical cross-linking are presented. The properties of the starch microspheres are affected by the production method, which also influences what applications they are suited for, and how active substances can be included in the microspheres. The current and potential applications of starch microspheres in drug delivery, vascular occlusion, and advanced wound care are... (More)

Starch is generally regarded as safe for human consumption and has therefore attracted interest for several applications as medicinal products. This chapter focuses specifically on starch microspheres as carriers for drug delivery and as a medical device for, for example, vascular occlusion. Several methods for the preparation of starch microspheres by chemical or physical cross-linking are presented. The properties of the starch microspheres are affected by the production method, which also influences what applications they are suited for, and how active substances can be included in the microspheres. The current and potential applications of starch microspheres in drug delivery, vascular occlusion, and advanced wound care are reviewed.

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Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Advanced wound care, Antisolvent precipitation, Aqueous two-phase systems, Chemical cross-linking, Drug delivery, Physical cross-linking, Spray drying, Starch microspheres, Vascular occlusion
host publication
Starch in Food : Structure, Function, and Applications - Structure, Function, and Applications
editor
Nilsson, Lars
edition
Third Edition
pages
15 pages
publisher
Elsevier
external identifiers
  • scopus:85199092858
ISBN
978-0-323-96103-5
978-0-323-96102-8
DOI
10.1016/B978-0-323-96102-8.00020-6
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2024 Elsevier Ltd. All rights reserved.
id
2397526b-697d-4ba7-97e5-047a0edf6b3a
date added to LUP
2024-09-02 22:47:47
date last changed
2025-07-09 03:22:26
@inbook{2397526b-697d-4ba7-97e5-047a0edf6b3a,
  abstract     = {{<p>Starch is generally regarded as safe for human consumption and has therefore attracted interest for several applications as medicinal products. This chapter focuses specifically on starch microspheres as carriers for drug delivery and as a medical device for, for example, vascular occlusion. Several methods for the preparation of starch microspheres by chemical or physical cross-linking are presented. The properties of the starch microspheres are affected by the production method, which also influences what applications they are suited for, and how active substances can be included in the microspheres. The current and potential applications of starch microspheres in drug delivery, vascular occlusion, and advanced wound care are reviewed.</p>}},
  author       = {{Fureby, Anna Millqvist and Gidlöf, Zandra and Wahlgren, Marie}},
  booktitle    = {{Starch in Food : Structure, Function, and Applications}},
  editor       = {{Nilsson, Lars}},
  isbn         = {{978-0-323-96103-5}},
  keywords     = {{Advanced wound care; Antisolvent precipitation; Aqueous two-phase systems; Chemical cross-linking; Drug delivery; Physical cross-linking; Spray drying; Starch microspheres; Vascular occlusion}},
  language     = {{eng}},
  month        = {{01}},
  pages        = {{487--501}},
  publisher    = {{Elsevier}},
  title        = {{The use of starch microspheres and nanoparticles in pharmaceutical applications}},
  url          = {{http://dx.doi.org/10.1016/B978-0-323-96102-8.00020-6}},
  doi          = {{10.1016/B978-0-323-96102-8.00020-6}},
  year         = {{2024}},
}