Detailed Analysis of Focal Chromosome Arm 1q and 6p Amplifications in Urothelial Carcinoma Reveals Complex Genomic Events on 1q, and SOX4 as a Possible Auxiliary Target on 6p.
Eriksson, Pontus LU ; Aine, Mattias LU ; Sjödahl, Gottfrid LU ; Staaf, Johan LU
; Lindgren, David
LU
and Höglund, Mattias
LU
(2013)
In PLoS ONE
8(6).
- Abstract
- Urothelial carcinoma shows frequent amplifications at 6p22 and 1q21-24. The main target gene at 6p22 is believed to be E2F3, frequently co-amplified with CDKAL1 and SOX4. There are however reports on 6p22 amplifications that do not include E2F3. Previous analyses have identified frequent aberrations occurring at 1q21-24. However, due to complex rearrangements it has been difficult to identify specific 1q21-24 target regions and genes.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3956190
- author
- Eriksson, Pontus
LU
; Aine, Mattias
LU
; Sjödahl, Gottfrid
LU
; Staaf, Johan
LU
; Lindgren, David
LU
and Höglund, Mattias
LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS ONE
- volume
- 8
- issue
- 6
- article number
- e67222
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- wos:000320576400179
- pmid:23825644
- scopus:84879176415
- pmid:23825644
- ISSN
- 1932-6203
- DOI
- 10.1371/journal.pone.0067222
- language
- English
- LU publication?
- yes
- additional info
- Department affilation moved from v1000583 (Molecular Tumour Biology) to v1000562 (Department of Translational Medicine) on 2016-01-18 14:41:47.
- id
- 248b7d1f-99aa-40c9-9dda-689bca79900d (old id 3956190)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23825644?dopt=Abstract
- date added to LUP
- 2016-04-01 13:00:53
- date last changed
- 2022-04-06 02:06:22
@article{248b7d1f-99aa-40c9-9dda-689bca79900d,
abstract = {{Urothelial carcinoma shows frequent amplifications at 6p22 and 1q21-24. The main target gene at 6p22 is believed to be E2F3, frequently co-amplified with CDKAL1 and SOX4. There are however reports on 6p22 amplifications that do not include E2F3. Previous analyses have identified frequent aberrations occurring at 1q21-24. However, due to complex rearrangements it has been difficult to identify specific 1q21-24 target regions and genes.}},
author = {{Eriksson, Pontus and Aine, Mattias and Sjödahl, Gottfrid and Staaf, Johan and Lindgren, David and Höglund, Mattias}},
issn = {{1932-6203}},
language = {{eng}},
number = {{6}},
publisher = {{Public Library of Science (PLoS)}},
series = {{PLoS ONE}},
title = {{Detailed Analysis of Focal Chromosome Arm 1q and 6p Amplifications in Urothelial Carcinoma Reveals Complex Genomic Events on 1q, and SOX4 as a Possible Auxiliary Target on 6p.}},
url = {{https://lup.lub.lu.se/search/files/3105442/4146192}},
doi = {{10.1371/journal.pone.0067222}},
volume = {{8}},
year = {{2013}},
}