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A colorectal cancer diet quality index is inversely associated with colorectal cancer in the Malmö diet and cancer study

Vulcan, Alexandra LU ; Ericson, Ulrika LU ; Manjer, Jonas LU and Ohlsson, Bodil LU (2019) In European Journal of Cancer Prevention 28(6). p.463-471
Abstract

The World Cancer Research Fund International has concluded strong evidence for that high intake of dairy products and foods containing dietary fiber and low intake of processed meat are associated with decreased risk of colorectal cancer (CRC). As food items are consumed together, it is important to study dietary patterns. The aim of the present study was to examine the association between an a priori constructed dietary index and incident CRC and between intake of processed meat, fiber, and dairy products and CRC. In the Malmö Diet and Cancer study cohort, 923 cases of CRC were identified, during 502 136 person-years of follow-up. A Colorectal Diet Quality Index (CDQI) was constructed regarding intakes of processed meat, fiber, and... (More)

The World Cancer Research Fund International has concluded strong evidence for that high intake of dairy products and foods containing dietary fiber and low intake of processed meat are associated with decreased risk of colorectal cancer (CRC). As food items are consumed together, it is important to study dietary patterns. The aim of the present study was to examine the association between an a priori constructed dietary index and incident CRC and between intake of processed meat, fiber, and dairy products and CRC. In the Malmö Diet and Cancer study cohort, 923 cases of CRC were identified, during 502 136 person-years of follow-up. A Colorectal Diet Quality Index (CDQI) was constructed regarding intakes of processed meat, fiber, and dairy products in relation to CRC. Higher index indicated a higher dietary quality. Higher CDQI was associated with lower risk of CRC [hazard ratios (HR): 0.57 for highest compared with lowest quintile; 95% confidence interval (CI): 0.43, 0.75; P<0.001]. Intake of dairy products was inversely associated with risk of CRC [HR for highest vs. lowest quintile was 0.77 (CI: 0.62, 0.96); P = 0.008], as was dietary fiber [HR for highest vs. lowest quintile was 0.77 (CI: 0.61, 0.98); P = 0.043]. High intake of processed meat was associated with CRC [HR for highest vs. lowest quintile was 1.31; CI: 1.05, 1.63; P = 0.012]. High adherence to a predefined CRC-specific diet quality index was inversely associated with the risk of CRC and gave a stronger association with CRC, than when analyzing the components of the CDQI individually.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Colorectal Diet Quality Index, colorectal neoplasms, dietary index, Malmö Diet and Cancer study, modified diet history method
in
European Journal of Cancer Prevention
volume
28
issue
6
pages
9 pages
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:30422929
  • scopus:85072770913
ISSN
0959-8278
DOI
10.1097/CEJ.0000000000000486
language
English
LU publication?
yes
id
260733c4-adc5-4d3a-8dec-e7c86ce73ef7
date added to LUP
2020-09-15 13:22:23
date last changed
2024-02-17 00:19:10
@article{260733c4-adc5-4d3a-8dec-e7c86ce73ef7,
  abstract     = {{<p>The World Cancer Research Fund International has concluded strong evidence for that high intake of dairy products and foods containing dietary fiber and low intake of processed meat are associated with decreased risk of colorectal cancer (CRC). As food items are consumed together, it is important to study dietary patterns. The aim of the present study was to examine the association between an a priori constructed dietary index and incident CRC and between intake of processed meat, fiber, and dairy products and CRC. In the Malmö Diet and Cancer study cohort, 923 cases of CRC were identified, during 502 136 person-years of follow-up. A Colorectal Diet Quality Index (CDQI) was constructed regarding intakes of processed meat, fiber, and dairy products in relation to CRC. Higher index indicated a higher dietary quality. Higher CDQI was associated with lower risk of CRC [hazard ratios (HR): 0.57 for highest compared with lowest quintile; 95% confidence interval (CI): 0.43, 0.75; P&lt;0.001]. Intake of dairy products was inversely associated with risk of CRC [HR for highest vs. lowest quintile was 0.77 (CI: 0.62, 0.96); P = 0.008], as was dietary fiber [HR for highest vs. lowest quintile was 0.77 (CI: 0.61, 0.98); P = 0.043]. High intake of processed meat was associated with CRC [HR for highest vs. lowest quintile was 1.31; CI: 1.05, 1.63; P = 0.012]. High adherence to a predefined CRC-specific diet quality index was inversely associated with the risk of CRC and gave a stronger association with CRC, than when analyzing the components of the CDQI individually.</p>}},
  author       = {{Vulcan, Alexandra and Ericson, Ulrika and Manjer, Jonas and Ohlsson, Bodil}},
  issn         = {{0959-8278}},
  keywords     = {{Colorectal Diet Quality Index; colorectal neoplasms; dietary index; Malmö Diet and Cancer study; modified diet history method}},
  language     = {{eng}},
  month        = {{11}},
  number       = {{6}},
  pages        = {{463--471}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{European Journal of Cancer Prevention}},
  title        = {{A colorectal cancer diet quality index is inversely associated with colorectal cancer in the Malmö diet and cancer study}},
  url          = {{http://dx.doi.org/10.1097/CEJ.0000000000000486}},
  doi          = {{10.1097/CEJ.0000000000000486}},
  volume       = {{28}},
  year         = {{2019}},
}