Advanced

The prospective association between total and type of fish intake and type 2 diabetes in 8 European countries: EPIC-InterAct Study

Patel, Pinal S.; Forouhi, Nita G.; Kuijsten, Anneleen; Schulze, Matthias B.; van Woudenbergh, Geertruida J.; Ardanaz, Eva; Amiano, Pilar; Arriola, Larraitz; Balkau, Beverley and Barricarte, Aurelio, et al. (2012) In American Journal of Clinical Nutrition 95(6). p.1445-1453
Abstract
Background: Epidemiologic evidence of an association between fish intake and type 2 diabetes (T2D) is inconsistent and unresolved. Objective: The objective was to examine the association between total and type of fish intake and T2D in 8 European countries. Design: This was a case-cohort study, nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) study, with 3.99 million person-years of follow-up, 12,403 incident diabetes cases, and a random subcohort of 16,835 individuals from 8 European countries. Habitual fish intake (lean fish, fatty fish, total fish, shellfish, and combined fish and shellfish) was assessed by country-specific dietary questionnaires. HRs were estimated in each country by using... (More)
Background: Epidemiologic evidence of an association between fish intake and type 2 diabetes (T2D) is inconsistent and unresolved. Objective: The objective was to examine the association between total and type of fish intake and T2D in 8 European countries. Design: This was a case-cohort study, nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) study, with 3.99 million person-years of follow-up, 12,403 incident diabetes cases, and a random subcohort of 16,835 individuals from 8 European countries. Habitual fish intake (lean fish, fatty fish, total fish, shellfish, and combined fish and shellfish) was assessed by country-specific dietary questionnaires. HRs were estimated in each country by using Prentice-weighted Cox regression models and pooled by using a random-effects meta-analysis. Results: No overall association was found between combined fish and shellfish intake and incident T2D per quartile (adjusted HR: 1.00; 95% Cl: 0.94, 1.06; P-trend = 0.99). Total fish, lean fish, and shellfish intakes separately were also not associated with T2D, but fatty fish intake was weakly inversely associated with T2D: adjusted HR per quartile 0.97 (0.94, 1.00), with an HR of 0.84 (0.70, 1.01), 0.85 (0.76, 0.95), and 0.87 (0.78, 0.97) for a comparison of the second, third, and fourth quartiles with the lowest quartile of intake, respectively (P-trend = 0.06). Conclusions: These findings suggest that lean fish, total fish, and shellfish intakes are not associated with incident diabetes but that fatty fish intake may be weakly inversely associated. Replication of these findings in other populations and investigation of the mechanisms underlying these associations are warranted. Meanwhile, current public health recommendations on fish intake should remain unchanged. Am J Clin Nutr 2012;95:1445-53, (Less)
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
American Journal of Clinical Nutrition
volume
95
issue
6
pages
1445 - 1453
publisher
American Society for Clinical Nutrition
external identifiers
  • wos:000304337600020
  • scopus:84861550709
ISSN
1938-3207
DOI
10.3945/ajcn.111.029314
language
English
LU publication?
yes
id
e333e780-8e43-45a7-b3af-8347cab1b63f (old id 2799594)
date added to LUP
2012-07-03 10:24:51
date last changed
2017-10-22 04:18:57
@article{e333e780-8e43-45a7-b3af-8347cab1b63f,
  abstract     = {Background: Epidemiologic evidence of an association between fish intake and type 2 diabetes (T2D) is inconsistent and unresolved. Objective: The objective was to examine the association between total and type of fish intake and T2D in 8 European countries. Design: This was a case-cohort study, nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) study, with 3.99 million person-years of follow-up, 12,403 incident diabetes cases, and a random subcohort of 16,835 individuals from 8 European countries. Habitual fish intake (lean fish, fatty fish, total fish, shellfish, and combined fish and shellfish) was assessed by country-specific dietary questionnaires. HRs were estimated in each country by using Prentice-weighted Cox regression models and pooled by using a random-effects meta-analysis. Results: No overall association was found between combined fish and shellfish intake and incident T2D per quartile (adjusted HR: 1.00; 95% Cl: 0.94, 1.06; P-trend = 0.99). Total fish, lean fish, and shellfish intakes separately were also not associated with T2D, but fatty fish intake was weakly inversely associated with T2D: adjusted HR per quartile 0.97 (0.94, 1.00), with an HR of 0.84 (0.70, 1.01), 0.85 (0.76, 0.95), and 0.87 (0.78, 0.97) for a comparison of the second, third, and fourth quartiles with the lowest quartile of intake, respectively (P-trend = 0.06). Conclusions: These findings suggest that lean fish, total fish, and shellfish intakes are not associated with incident diabetes but that fatty fish intake may be weakly inversely associated. Replication of these findings in other populations and investigation of the mechanisms underlying these associations are warranted. Meanwhile, current public health recommendations on fish intake should remain unchanged. Am J Clin Nutr 2012;95:1445-53,},
  author       = {Patel, Pinal S. and Forouhi, Nita G. and Kuijsten, Anneleen and Schulze, Matthias B. and van Woudenbergh, Geertruida J. and Ardanaz, Eva and Amiano, Pilar and Arriola, Larraitz and Balkau, Beverley and Barricarte, Aurelio and Beulens, Joline W. J. and Boeing, Heiner and Buijsse, Brian and Crowe, Francesca L. and de Lauzon-Guillan, Blandine and Fagherazzi, Guy and Franks, Paul and Gonzalez, Carlos and Grioni, Sara and Halkjaer, Jytte and Maria Huerta, Jose and Key, Timothy J. and Kuehn, Tilman and Masala, Giovanna and Nilsson, Peter and Overvad, Kim and Panico, Salvatore and Ramon Quiros, Jose and Rolandsson, Olov and Sacerdote, Carlotta and Sanchez, Maria-Jose and Schmidt, Erik B. and Slimani, Nadia and Spijkerman, Annemieke M. W. and Teucher, Birgit and Tjonneland, Anne and Tormo, Maria-Jose and Tumino, Rosario and van der A, Daphne L. and van der Schouw, Yvonne T. and Sharp, Stephen J. and Langenberg, Claudia and Feskens, Edith J. M. and Riboli, Elio and Wareham, Nicholas J.},
  issn         = {1938-3207},
  language     = {eng},
  number       = {6},
  pages        = {1445--1453},
  publisher    = {American Society for Clinical Nutrition},
  series       = {American Journal of Clinical Nutrition},
  title        = {The prospective association between total and type of fish intake and type 2 diabetes in 8 European countries: EPIC-InterAct Study},
  url          = {http://dx.doi.org/10.3945/ajcn.111.029314},
  volume       = {95},
  year         = {2012},
}