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Bioavailability of selenium from bovine milk as assessed in subjects with ileostomy

Chen, Jun LU ; Lindmark Månsson, Helena LU ; Drevelius, M; Tidehag, P; Hallmans, G; Hertervig, Erik LU ; Nilsson, Åke LU and Åkesson, Björn LU (2004) In European Journal of Clinical Nutrition 58(2). p.350-355
Abstract
Objective: To assess the absorption of dietary selenium in humans, especially of milk selenium. Design: 1-day meal studies in subjects with ileostomy. Setting: Hospital outpatient clinics. Subjects: Three subjects in the pilot study and nine subjects in the main study ( eight men/four women). Intervention: Different beverages, 1 l/day, were given in addition to basal diets ( soft drink, 1 week; low-fat milk, 3 weeks; fermented low-fat milk, 3 weeks and soft drink, 1 week). Ileostomy effluents were collected during the last 2 days in each of the four periods. Results: On days when the subjects were given 1 l of low-fat milk, the estimated fractional absorption of total dietary selenium was 65.5 (2.3)% ( mean (s. d.), n = 18), which was... (More)
Objective: To assess the absorption of dietary selenium in humans, especially of milk selenium. Design: 1-day meal studies in subjects with ileostomy. Setting: Hospital outpatient clinics. Subjects: Three subjects in the pilot study and nine subjects in the main study ( eight men/four women). Intervention: Different beverages, 1 l/day, were given in addition to basal diets ( soft drink, 1 week; low-fat milk, 3 weeks; fermented low-fat milk, 3 weeks and soft drink, 1 week). Ileostomy effluents were collected during the last 2 days in each of the four periods. Results: On days when the subjects were given 1 l of low-fat milk, the estimated fractional absorption of total dietary selenium was 65.5 (2.3)% ( mean (s. d.), n = 18), which was similar to the value when fermented low-fat milk was given (64.1 (3.2)%). However, both the calculated amount of milk selenium absorbed (10.9 (2.4) vs 9.4 (1.7) mg selenium) and its fractional absorption (73.3 (16.1) vs 64.1 (11.2)%, n = 18) were significantly higher for milk than for fermented milk. Conclusions: Selenium from milk and other sources is well absorbed in subjects with ileostomy. The real absorption may be even higher than the values shown. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
selenoprotein, fermentation, milk, selenium bioavailability, ileostomy
in
European Journal of Clinical Nutrition
volume
58
issue
2
pages
350 - 355
publisher
Nature Publishing Group
external identifiers
  • pmid:14749757
  • wos:000188511800021
  • scopus:1342289674
ISSN
1476-5640
DOI
10.1038/sj.ejcn.1601789
language
English
LU publication?
yes
id
cd60ca58-7e13-4ccc-93de-cd8b95311abe (old id 289498)
date added to LUP
2007-10-17 16:49:31
date last changed
2017-01-15 04:05:38
@article{cd60ca58-7e13-4ccc-93de-cd8b95311abe,
  abstract     = {Objective: To assess the absorption of dietary selenium in humans, especially of milk selenium. Design: 1-day meal studies in subjects with ileostomy. Setting: Hospital outpatient clinics. Subjects: Three subjects in the pilot study and nine subjects in the main study ( eight men/four women). Intervention: Different beverages, 1 l/day, were given in addition to basal diets ( soft drink, 1 week; low-fat milk, 3 weeks; fermented low-fat milk, 3 weeks and soft drink, 1 week). Ileostomy effluents were collected during the last 2 days in each of the four periods. Results: On days when the subjects were given 1 l of low-fat milk, the estimated fractional absorption of total dietary selenium was 65.5 (2.3)% ( mean (s. d.), n = 18), which was similar to the value when fermented low-fat milk was given (64.1 (3.2)%). However, both the calculated amount of milk selenium absorbed (10.9 (2.4) vs 9.4 (1.7) mg selenium) and its fractional absorption (73.3 (16.1) vs 64.1 (11.2)%, n = 18) were significantly higher for milk than for fermented milk. Conclusions: Selenium from milk and other sources is well absorbed in subjects with ileostomy. The real absorption may be even higher than the values shown.},
  author       = {Chen, Jun and Lindmark Månsson, Helena and Drevelius, M and Tidehag, P and Hallmans, G and Hertervig, Erik and Nilsson, Åke and Åkesson, Björn},
  issn         = {1476-5640},
  keyword      = {selenoprotein,fermentation,milk,selenium bioavailability,ileostomy},
  language     = {eng},
  number       = {2},
  pages        = {350--355},
  publisher    = {Nature Publishing Group},
  series       = {European Journal of Clinical Nutrition},
  title        = {Bioavailability of selenium from bovine milk as assessed in subjects with ileostomy},
  url          = {http://dx.doi.org/10.1038/sj.ejcn.1601789},
  volume       = {58},
  year         = {2004},
}