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Assessing toxicity of PM2.5 from indoor sources and during exposure in private homes

Wierzbicka, Aneta LU orcid ; Enarsson, Jonas LU ; Saber, Anne Thoustrup ; Strandberg, Bo LU ; Pagels, Joakim LU and Jacobsen, Nicklas Raun (2024) 18th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2024
Abstract

Toxicological testing in mice was conducted on PM2.5 particles from stressed burning of two types of candles (white and blue) and on PM2.5 collected indoor and outdoor of fifteen occupied homes in southern Sweden. As an indicator of toxicity, the ability to generate Reactive Oxygen Species (ROS) was also assessed for all pooled samples: candle white, candle blue, indoor, and outdoor. Higher toxicity of indoor particles and from white candles in comparison to outdoor ones highlight the need for studies assessing toxicity of particles from indoor sources and mixtures that we are exposed to while indoors. ROS formation potential can be an interesting option to screen particles for its toxicity but the sensitivity of... (More)

Toxicological testing in mice was conducted on PM2.5 particles from stressed burning of two types of candles (white and blue) and on PM2.5 collected indoor and outdoor of fifteen occupied homes in southern Sweden. As an indicator of toxicity, the ability to generate Reactive Oxygen Species (ROS) was also assessed for all pooled samples: candle white, candle blue, indoor, and outdoor. Higher toxicity of indoor particles and from white candles in comparison to outdoor ones highlight the need for studies assessing toxicity of particles from indoor sources and mixtures that we are exposed to while indoors. ROS formation potential can be an interesting option to screen particles for its toxicity but the sensitivity of different assays to specific compounds indicates that a range of assays is needed for toxicity screening.

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Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
aerosols, indoor particles, indoor sources, physicochemical characteristics, toxicity
host publication
18th Conference of the International Society of Indoor Air Quality and Climate, INDOOR AIR 2024 - Conference Program and Proceedings
publisher
International Society of Indoor Air Quality and Climate (ISIAQ)
conference name
18th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2024
conference location
Honolulu, United States
conference dates
2024-07-07 - 2024-07-11
external identifiers
  • scopus:85210831262
ISBN
9798331306816
language
English
LU publication?
yes
id
28e0f18b-af6f-4cbe-a74b-86f681c4703c
date added to LUP
2025-01-28 10:36:47
date last changed
2025-06-19 14:45:31
@inproceedings{28e0f18b-af6f-4cbe-a74b-86f681c4703c,
  abstract     = {{<p>Toxicological testing in mice was conducted on PM<sub>2.5</sub> particles from stressed burning of two types of candles (white and blue) and on PM<sub>2.5</sub> collected indoor and outdoor of fifteen occupied homes in southern Sweden. As an indicator of toxicity, the ability to generate Reactive Oxygen Species (ROS) was also assessed for all pooled samples: candle white, candle blue, indoor, and outdoor. Higher toxicity of indoor particles and from white candles in comparison to outdoor ones highlight the need for studies assessing toxicity of particles from indoor sources and mixtures that we are exposed to while indoors. ROS formation potential can be an interesting option to screen particles for its toxicity but the sensitivity of different assays to specific compounds indicates that a range of assays is needed for toxicity screening.</p>}},
  author       = {{Wierzbicka, Aneta and Enarsson, Jonas and Saber, Anne Thoustrup and Strandberg, Bo and Pagels, Joakim and Jacobsen, Nicklas Raun}},
  booktitle    = {{18th Conference of the International Society of Indoor Air Quality and Climate, INDOOR AIR 2024 - Conference Program and Proceedings}},
  isbn         = {{9798331306816}},
  keywords     = {{aerosols; indoor particles; indoor sources; physicochemical characteristics; toxicity}},
  language     = {{eng}},
  publisher    = {{International Society of Indoor Air Quality and Climate (ISIAQ)}},
  title        = {{Assessing toxicity of PM<sub>2.5</sub> from indoor sources and during exposure in private homes}},
  year         = {{2024}},
}