Oral administration of live exopolysaccharide-producing Pediococcus parvulus, but not purified exopolysaccharide suppressed Enterobacteriaceae without affecting bacterial diversity in caecum of mice.
(2013) In Applied and Environmental Microbiology 79(16). p.5030-5037- Abstract
- Growing evidence indicates that the gut microbiota could have an important role in the development of diet and lifestyle induced diseases. It has been shown that modulation of the gut microbiota by means of probiotics and prebiotics could improve host health. An oat based product fermented by the exopolysaccharide (EPS)-producing Pediococcus parvulus 2.6 has been reported to have a bifidogenic effect. To find out whether the effect could be attributed to the EPS or the bacterium, mice were fed a diet supplemented with 2 % purified EPS or 10(8) CFU/g of live P. parvulus 2.6 for six weeks. Both supplementations altered the gut microbiota composition but in different directions. Purified EPS not only significantly lowered the microbial... (More)
- Growing evidence indicates that the gut microbiota could have an important role in the development of diet and lifestyle induced diseases. It has been shown that modulation of the gut microbiota by means of probiotics and prebiotics could improve host health. An oat based product fermented by the exopolysaccharide (EPS)-producing Pediococcus parvulus 2.6 has been reported to have a bifidogenic effect. To find out whether the effect could be attributed to the EPS or the bacterium, mice were fed a diet supplemented with 2 % purified EPS or 10(8) CFU/g of live P. parvulus 2.6 for six weeks. Both supplementations altered the gut microbiota composition but in different directions. Purified EPS not only significantly lowered the microbial diversity (P < 0.001) but decreased the bifidobacterial population (P = 0.01). In contrast, the live EPS-producing P. parvulus 2.6 antagonized Enterobacteriaceae without disturbing the homeostasis of the caecal microbiota. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3913336
- author
- Lindström, Cecilia LU ; Xu, Jie LU ; Öste, Rickard LU ; Holst, Olle LU and Molin, Göran LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Applied and Environmental Microbiology
- volume
- 79
- issue
- 16
- pages
- 5030 - 5037
- publisher
- American Society for Microbiology
- external identifiers
-
- wos:000322161700030
- pmid:23770909
- scopus:84881019392
- ISSN
- 0099-2240
- DOI
- 10.1128/AEM.01456-13
- project
- ANTIDIABETIC FOOD CENTRE
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Applied Nutrition and Food Chemistry (011001300), Biotechnology (LTH) (011001037)
- id
- a1915c64-568e-4ed3-9acd-df6f35eb9a7f (old id 3913336)
- date added to LUP
- 2016-04-01 10:00:36
- date last changed
- 2023-08-30 15:26:08
@article{a1915c64-568e-4ed3-9acd-df6f35eb9a7f,
abstract = {{Growing evidence indicates that the gut microbiota could have an important role in the development of diet and lifestyle induced diseases. It has been shown that modulation of the gut microbiota by means of probiotics and prebiotics could improve host health. An oat based product fermented by the exopolysaccharide (EPS)-producing Pediococcus parvulus 2.6 has been reported to have a bifidogenic effect. To find out whether the effect could be attributed to the EPS or the bacterium, mice were fed a diet supplemented with 2 % purified EPS or 10(8) CFU/g of live P. parvulus 2.6 for six weeks. Both supplementations altered the gut microbiota composition but in different directions. Purified EPS not only significantly lowered the microbial diversity (P < 0.001) but decreased the bifidobacterial population (P = 0.01). In contrast, the live EPS-producing P. parvulus 2.6 antagonized Enterobacteriaceae without disturbing the homeostasis of the caecal microbiota.}},
author = {{Lindström, Cecilia and Xu, Jie and Öste, Rickard and Holst, Olle and Molin, Göran}},
issn = {{0099-2240}},
language = {{eng}},
number = {{16}},
pages = {{5030--5037}},
publisher = {{American Society for Microbiology}},
series = {{Applied and Environmental Microbiology}},
title = {{Oral administration of live exopolysaccharide-producing Pediococcus parvulus, but not purified exopolysaccharide suppressed Enterobacteriaceae without affecting bacterial diversity in caecum of mice.}},
url = {{https://lup.lub.lu.se/search/files/1476279/4124611.pdf}},
doi = {{10.1128/AEM.01456-13}},
volume = {{79}},
year = {{2013}},
}