Advanced

Effect of feeding colostrum versus exogenous immunoglobulin G on gastrointestinal structure and enteric nervous system in newborn pigs

Wolinski, J.; Slupecka, M.; Weström, Björn LU ; Prykhodko, O.; Ochniewicz, P.; Arciszewski, M.; Ekblad, E.; Szwiec, K.; Ushakova, X and Skibo, G., et al. (2012) In Journal of Animal Science 90. p.327-329
Abstract
Colostrum is an indispensable source of antibodies (IgG) protecting the newborn pig against infection. We studied the effect of feeding colostrum and purified IgG on early structure and development of the gastrointestinal tract (GIT). Newborn littermate pigs were fed either colostrum, an elemental diet (ED), or an ED supplemented with purified serum IgG (ED + IgG) for 24 h or then only ED up to 72 h. Afterwards, pigs were slaughtered. Colostrum-fed pigs or ED supplemented with IgG (ED + IgG) increased thickness (P < 0.001) of stomach mucosa and muscularis (P < 0.05) compared to the ED group not receiving IgG. Feeding an ED supplemented with IgG improved morphology of the GIT towards that of colostrum-fed piglets and indicates a... (More)
Colostrum is an indispensable source of antibodies (IgG) protecting the newborn pig against infection. We studied the effect of feeding colostrum and purified IgG on early structure and development of the gastrointestinal tract (GIT). Newborn littermate pigs were fed either colostrum, an elemental diet (ED), or an ED supplemented with purified serum IgG (ED + IgG) for 24 h or then only ED up to 72 h. Afterwards, pigs were slaughtered. Colostrum-fed pigs or ED supplemented with IgG (ED + IgG) increased thickness (P < 0.001) of stomach mucosa and muscularis (P < 0.05) compared to the ED group not receiving IgG. Feeding an ED supplemented with IgG improved morphology of the GIT towards that of colostrum-fed piglets and indicates a beneficial effect of IgG on GIT development in neonatal pigs. Immunohistochemical studies indicate that ED feeding may influence the expression of nitric oxide synthase in jejunal myenteric (but not submucous) neurons of newborn pigs. (Less)
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
immunoglobulin G, elementary diet, colostrum, gut development
in
Journal of Animal Science
volume
90
pages
327 - 329
publisher
American Society of Animal Science
external identifiers
  • wos:000319673100105
  • scopus:84882634075
ISSN
1525-3163
DOI
10.2527/jas53926
language
English
LU publication?
yes
id
6243351c-c074-499e-ba7a-5dedf4c4b1f5 (old id 3931381)
date added to LUP
2013-07-15 14:53:27
date last changed
2017-08-20 03:21:10
@article{6243351c-c074-499e-ba7a-5dedf4c4b1f5,
  abstract     = {Colostrum is an indispensable source of antibodies (IgG) protecting the newborn pig against infection. We studied the effect of feeding colostrum and purified IgG on early structure and development of the gastrointestinal tract (GIT). Newborn littermate pigs were fed either colostrum, an elemental diet (ED), or an ED supplemented with purified serum IgG (ED + IgG) for 24 h or then only ED up to 72 h. Afterwards, pigs were slaughtered. Colostrum-fed pigs or ED supplemented with IgG (ED + IgG) increased thickness (P &lt; 0.001) of stomach mucosa and muscularis (P &lt; 0.05) compared to the ED group not receiving IgG. Feeding an ED supplemented with IgG improved morphology of the GIT towards that of colostrum-fed piglets and indicates a beneficial effect of IgG on GIT development in neonatal pigs. Immunohistochemical studies indicate that ED feeding may influence the expression of nitric oxide synthase in jejunal myenteric (but not submucous) neurons of newborn pigs.},
  author       = {Wolinski, J. and Slupecka, M. and Weström, Björn and Prykhodko, O. and Ochniewicz, P. and Arciszewski, M. and Ekblad, E. and Szwiec, K. and Ushakova, X and Skibo, G. and Kovalenko, T. and Osadchenko, I. and Goncharova, K. and Botermans, J. and Pierzynowski, Stefan},
  issn         = {1525-3163},
  keyword      = {immunoglobulin G,elementary diet,colostrum,gut development},
  language     = {eng},
  pages        = {327--329},
  publisher    = {American Society of Animal Science},
  series       = {Journal of Animal Science},
  title        = {Effect of feeding colostrum versus exogenous immunoglobulin G on gastrointestinal structure and enteric nervous system in newborn pigs},
  url          = {http://dx.doi.org/10.2527/jas53926},
  volume       = {90},
  year         = {2012},
}