Hemoglobin induces inflammation after preterm intraventricular hemorrhage by methemoglobin formation.
(2013) In Journal of Neuroinflammation 10(Aug.,6).- Abstract
- Cerebral intraventricular hemorrhage (IVH) is a major cause of severe neurodevelopmental impairment in preterm infants. To date, no therapy is available that prevents infants from developing serious neurological disability following IVH. Thus, to develop treatment strategies for IVH, it is essential to characterize the initial sequence of molecular events that leads to brain damage. In this study, we investigated extracellular hemoglobin (Hb) as a causal initiator of inflammation in preterm IVH.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4006172
- author
- Gram, Magnus LU ; Sveinsdottir, Snjolaug LU ; Ruscher, Karsten LU ; Hansson, Stefan LU ; Cinthio, Magnus LU ; Åkerström, Bo LU and Ley, David LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Neuroinflammation
- volume
- 10
- issue
- Aug.,6
- article number
- 100
- publisher
- BioMed Central (BMC)
- external identifiers
-
- wos:000322901900001
- pmid:23915174
- scopus:84881056966
- pmid:23915174
- ISSN
- 1742-2094
- DOI
- 10.1186/1742-2094-10-100
- language
- English
- LU publication?
- yes
- id
- c0f3ef8d-c2c0-43d2-b724-8aac32be5349 (old id 4006172)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23915174?dopt=Abstract
- date added to LUP
- 2016-04-01 13:43:47
- date last changed
- 2022-04-29 21:43:25
@article{c0f3ef8d-c2c0-43d2-b724-8aac32be5349, abstract = {{Cerebral intraventricular hemorrhage (IVH) is a major cause of severe neurodevelopmental impairment in preterm infants. To date, no therapy is available that prevents infants from developing serious neurological disability following IVH. Thus, to develop treatment strategies for IVH, it is essential to characterize the initial sequence of molecular events that leads to brain damage. In this study, we investigated extracellular hemoglobin (Hb) as a causal initiator of inflammation in preterm IVH.}}, author = {{Gram, Magnus and Sveinsdottir, Snjolaug and Ruscher, Karsten and Hansson, Stefan and Cinthio, Magnus and Åkerström, Bo and Ley, David}}, issn = {{1742-2094}}, language = {{eng}}, number = {{Aug.,6}}, publisher = {{BioMed Central (BMC)}}, series = {{Journal of Neuroinflammation}}, title = {{Hemoglobin induces inflammation after preterm intraventricular hemorrhage by methemoglobin formation.}}, url = {{https://lup.lub.lu.se/search/files/3555145/4300673.pdf}}, doi = {{10.1186/1742-2094-10-100}}, volume = {{10}}, year = {{2013}}, }