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Intake of Energy and Protein is Associated with Overweight Risk at Age 5.5 Years : Results from the Prospective TEDDY Study

Beyerlein, Andreas; Uusitalo, Ulla M.; Virtanen, Suvi M.; Vehik, Kendra LU ; Yang, Jimin; Winkler, Christiane; Kersting, Mathilde; Koletzko, Sibylle; Schatz, Desmond and Aronsson, Carin Andrén LU , et al. (2017) In Obesity 25(8). p.1435-1441
Abstract

Objective: The associations of energy, protein, carbohydrate, and fat intake with weight status up to the age of 5.5 years were prospectively assessed in The Environmental Determinants of Diabetes in the Young (TEDDY) study. Methods: Food record data (over 3 days) and BMI measurements between 0.25 and 5.5 years were available from 5,563 children with an increased genetic risk for type 1 diabetes followed from shortly after birth. Odds ratios (ORs) were calculated for overweight and obesity by previous intake of energy, protein, carbohydrate, and fat with adjustment for potential confounders. Results: Having overweight or obesity at the age of 5.5 years was positively associated with mean energy intake in previous age intervals (e.g.,... (More)

Objective: The associations of energy, protein, carbohydrate, and fat intake with weight status up to the age of 5.5 years were prospectively assessed in The Environmental Determinants of Diabetes in the Young (TEDDY) study. Methods: Food record data (over 3 days) and BMI measurements between 0.25 and 5.5 years were available from 5,563 children with an increased genetic risk for type 1 diabetes followed from shortly after birth. Odds ratios (ORs) were calculated for overweight and obesity by previous intake of energy, protein, carbohydrate, and fat with adjustment for potential confounders. Results: Having overweight or obesity at the age of 5.5 years was positively associated with mean energy intake in previous age intervals (e.g., adjusted OR [95% CI] for overweight: 1.06 [1.04-1.09] per 100 kcal intake at the age of 4.5-5.0 years) and with protein intake after the age of 3.5 and 4.5 years, respectively (e.g., adjusted OR for overweight: 1.06 [1.03-1.09] per 1% of energy intake at the age of 4.5-5.0 years). The respective associations with carbohydrate and fat intake were less consistent. Conclusions: These findings indicate that energy and protein intake are positively associated with increased risk for overweight in childhood but yield no evidence for potential programming effects of protein intake in infancy.

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published
subject
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Obesity
volume
25
issue
8
pages
7 pages
publisher
Nature Publishing Group
external identifiers
  • scopus:85021321854
ISSN
1930-7381
DOI
10.1002/oby.21897
language
English
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yes
id
41477fe3-faea-4f49-8963-f93ebf0def64
date added to LUP
2018-01-25 12:16:16
date last changed
2018-09-16 04:52:56
@article{41477fe3-faea-4f49-8963-f93ebf0def64,
  abstract     = {<p>Objective: The associations of energy, protein, carbohydrate, and fat intake with weight status up to the age of 5.5 years were prospectively assessed in The Environmental Determinants of Diabetes in the Young (TEDDY) study. Methods: Food record data (over 3 days) and BMI measurements between 0.25 and 5.5 years were available from 5,563 children with an increased genetic risk for type 1 diabetes followed from shortly after birth. Odds ratios (ORs) were calculated for overweight and obesity by previous intake of energy, protein, carbohydrate, and fat with adjustment for potential confounders. Results: Having overweight or obesity at the age of 5.5 years was positively associated with mean energy intake in previous age intervals (e.g., adjusted OR [95% CI] for overweight: 1.06 [1.04-1.09] per 100 kcal intake at the age of 4.5-5.0 years) and with protein intake after the age of 3.5 and 4.5 years, respectively (e.g., adjusted OR for overweight: 1.06 [1.03-1.09] per 1% of energy intake at the age of 4.5-5.0 years). The respective associations with carbohydrate and fat intake were less consistent. Conclusions: These findings indicate that energy and protein intake are positively associated with increased risk for overweight in childhood but yield no evidence for potential programming effects of protein intake in infancy.</p>},
  author       = {Beyerlein, Andreas and Uusitalo, Ulla M. and Virtanen, Suvi M. and Vehik, Kendra and Yang, Jimin and Winkler, Christiane and Kersting, Mathilde and Koletzko, Sibylle and Schatz, Desmond and Aronsson, Carin Andrén and Elding Larsson, Helena and Krischer, Jeffrey P. and Ziegler, Anette G. and Norris, Jill M. and Hummel, Sandra and , },
  issn         = {1930-7381},
  language     = {eng},
  month        = {08},
  number       = {8},
  pages        = {1435--1441},
  publisher    = {Nature Publishing Group},
  series       = {Obesity},
  title        = {Intake of Energy and Protein is Associated with Overweight Risk at Age 5.5 Years : Results from the Prospective TEDDY Study},
  url          = {http://dx.doi.org/10.1002/oby.21897},
  volume       = {25},
  year         = {2017},
}