Oesophageal dysmotility, delayed gastric emptying and gastrointestinal symptoms in patients with diabetes mellitus.
Borg, Julia LU ; Melander, Olle LU
; Sundkvist, Göran
LU
; Olsson, Rolf
LU
; Thorsson, Ola
LU
; Ekberg, Olle
LU
and Ohlsson, Bodil
LU
(2007)
In Diabetic Medicine
24(11).
p.1235-1239
- Abstract
- Aims Gastroparesis is a common gastrointestinal complication in diabetes mellitus, whereas dysfunction in the other gastrointestinal organs has been less thoroughly investigated. Furthermore, it is not known whether there is any relationship between motility and dysmotility between these organs. The aim of this study was to examine whether diabetic patients with gastrointestinal symptoms also have motility disturbances in the oesophagus and stomach and, if so, whether there are any associations between these disturbances. Methods Thirty-one patients with diabetes mellitus who complained of gastrointestinal symptoms were asked to complete a questionnaire about their symptoms. They were further investigated with oesophageal manometry and... (More)
- Aims Gastroparesis is a common gastrointestinal complication in diabetes mellitus, whereas dysfunction in the other gastrointestinal organs has been less thoroughly investigated. Furthermore, it is not known whether there is any relationship between motility and dysmotility between these organs. The aim of this study was to examine whether diabetic patients with gastrointestinal symptoms also have motility disturbances in the oesophagus and stomach and, if so, whether there are any associations between these disturbances. Methods Thirty-one patients with diabetes mellitus who complained of gastrointestinal symptoms were asked to complete a questionnaire about their symptoms. They were further investigated with oesophageal manometry and gastric emptying scintigraphy. Results Fifty-eight per cent of the patients had abnormal oesophageal function, and 68% had delayed gastric emptying. Abdominal fullness was the only symptom that related to any dysfunction, and it was associated with delayed gastric emptying (P = 0.02). We did not find any relationship in motility or dysmotility between the oesophagus and the stomach. Conclusion Oesophageal dysmotility, as well as gastroparesis, are common in patients with diabetes who have gastrointestinal symptoms. It is important to investigate these patients further, to be able to reach an accurate diagnosis and instigate appropriate treatment. Our findings indicate that the oesophagus and the stomach function as separate organs and that pathology in one does not necessarily mean pathology in the other. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/606592
- author
- Borg, Julia
LU
; Melander, Olle
LU
; Sundkvist, Göran
LU
; Olsson, Rolf
LU
; Thorsson, Ola
LU
; Ekberg, Olle
LU
and Ohlsson, Bodil
LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- oesophageal dysmotility, mellitus, gastroparesis, diabetes, gastrointestinal symptoms, gastrointestinal dysmotility
- in
- Diabetic Medicine
- volume
- 24
- issue
- 11
- pages
- 1235 - 1239
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000250297500009
- scopus:35448991773
- pmid:17725632
- ISSN
- 1464-5491
- DOI
- 10.1111/j.1464-5491.2007.02236.x
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Clinical Physiology (013242300), Medical Radiology Unit (013241410), Diabetes Epidemiology and Neuropathy (013241560), Hypertension and Cardiovascular Disease (013242540), Chronic Inflammatory and Degenerative Diseases Research Unit (013242530), Clinical Physiology and Nuclear Medicine Unit (013242320)
- id
- 433ed4a4-9844-41c6-916a-ac391b840838 (old id 606592)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17725632&dopt=Abstract
- date added to LUP
- 2016-04-01 16:42:40
- date last changed
- 2024-01-11 13:16:31
@article{433ed4a4-9844-41c6-916a-ac391b840838,
abstract = {{Aims Gastroparesis is a common gastrointestinal complication in diabetes mellitus, whereas dysfunction in the other gastrointestinal organs has been less thoroughly investigated. Furthermore, it is not known whether there is any relationship between motility and dysmotility between these organs. The aim of this study was to examine whether diabetic patients with gastrointestinal symptoms also have motility disturbances in the oesophagus and stomach and, if so, whether there are any associations between these disturbances. Methods Thirty-one patients with diabetes mellitus who complained of gastrointestinal symptoms were asked to complete a questionnaire about their symptoms. They were further investigated with oesophageal manometry and gastric emptying scintigraphy. Results Fifty-eight per cent of the patients had abnormal oesophageal function, and 68% had delayed gastric emptying. Abdominal fullness was the only symptom that related to any dysfunction, and it was associated with delayed gastric emptying (P = 0.02). We did not find any relationship in motility or dysmotility between the oesophagus and the stomach. Conclusion Oesophageal dysmotility, as well as gastroparesis, are common in patients with diabetes who have gastrointestinal symptoms. It is important to investigate these patients further, to be able to reach an accurate diagnosis and instigate appropriate treatment. Our findings indicate that the oesophagus and the stomach function as separate organs and that pathology in one does not necessarily mean pathology in the other.}},
author = {{Borg, Julia and Melander, Olle and Sundkvist, Göran and Olsson, Rolf and Thorsson, Ola and Ekberg, Olle and Ohlsson, Bodil}},
issn = {{1464-5491}},
keywords = {{oesophageal dysmotility; mellitus; gastroparesis; diabetes; gastrointestinal symptoms; gastrointestinal dysmotility}},
language = {{eng}},
number = {{11}},
pages = {{1235--1239}},
publisher = {{Wiley-Blackwell}},
series = {{Diabetic Medicine}},
title = {{Oesophageal dysmotility, delayed gastric emptying and gastrointestinal symptoms in patients with diabetes mellitus.}},
url = {{https://lup.lub.lu.se/search/files/4757650/626096.pdf}},
doi = {{10.1111/j.1464-5491.2007.02236.x}},
volume = {{24}},
year = {{2007}},
}