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Health utilities of type 2 diabetes-related complications: a cross-sectional study in sweden.

Ahmad Kiadaliri, Aliasghar LU ; Gerdtham, Ulf LU ; Eliasson, Björn; Gudbjörnsdottir, Soffia; Svensson, Ann-Marie and Steen Carlsson, Katarina LU (2014) In International Journal of Environmental Research and Public Health 11(5). p.4939-4952
Abstract
This study estimates health utilities (HU) in Sweden for a range of type 2 diabetes-related complications using EQ-5D and two alternative tariffs (UK and Swedish) from 1757 patients with type 2 diabetes from the Swedish National Diabetes Register (NDR). Ordinary least squares were used for statistical analysis. Lower HU was found for female gender, younger age at diagnosis, higher BMI, and history of complications. Microvascular and macrovascular complications had the most negative effect on HU among women and men, respectively. The greatest decline in HU was associated with kidney disorders (-0.114) using the UK tariff and stroke (-0.059) using the Swedish tariff. Multiple stroke and non-acute ischaemic heart disease had higher negative... (More)
This study estimates health utilities (HU) in Sweden for a range of type 2 diabetes-related complications using EQ-5D and two alternative tariffs (UK and Swedish) from 1757 patients with type 2 diabetes from the Swedish National Diabetes Register (NDR). Ordinary least squares were used for statistical analysis. Lower HU was found for female gender, younger age at diagnosis, higher BMI, and history of complications. Microvascular and macrovascular complications had the most negative effect on HU among women and men, respectively. The greatest decline in HU was associated with kidney disorders (-0.114) using the UK tariff and stroke (-0.059) using the Swedish tariff. Multiple stroke and non-acute ischaemic heart disease had higher negative effect than a single event. With the UK tariff, each year elapsed since the last microvascular/macrovascular complication was associated with 0.013 and 0.007 units higher HU, respectively. We found important heterogeneities in effects of complications on HU in terms of gender, multiple event, and time. The Swedish tariff gave smaller estimates and so may result in less cost-effective interventions than the UK tariff. These results suggest that incorporating subgroup-specific HU in cost-utility analyses might provide more insight for informed decision-making. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
International Journal of Environmental Research and Public Health
volume
11
issue
5
pages
4939 - 4952
publisher
Multidisciplinary Digital Publishing Institute (MDPI)
external identifiers
  • pmid:24810579
  • wos:000337251900023
  • scopus:84900520904
ISSN
1660-4601
DOI
10.3390/ijerph110504939
language
English
LU publication?
yes
id
0beb7636-ff1b-46be-b12b-7faba9b9220c (old id 4455654)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24810579?dopt=Abstract
date added to LUP
2014-06-03 21:15:55
date last changed
2017-03-26 03:21:34
@article{0beb7636-ff1b-46be-b12b-7faba9b9220c,
  abstract     = {This study estimates health utilities (HU) in Sweden for a range of type 2 diabetes-related complications using EQ-5D and two alternative tariffs (UK and Swedish) from 1757 patients with type 2 diabetes from the Swedish National Diabetes Register (NDR). Ordinary least squares were used for statistical analysis. Lower HU was found for female gender, younger age at diagnosis, higher BMI, and history of complications. Microvascular and macrovascular complications had the most negative effect on HU among women and men, respectively. The greatest decline in HU was associated with kidney disorders (-0.114) using the UK tariff and stroke (-0.059) using the Swedish tariff. Multiple stroke and non-acute ischaemic heart disease had higher negative effect than a single event. With the UK tariff, each year elapsed since the last microvascular/macrovascular complication was associated with 0.013 and 0.007 units higher HU, respectively. We found important heterogeneities in effects of complications on HU in terms of gender, multiple event, and time. The Swedish tariff gave smaller estimates and so may result in less cost-effective interventions than the UK tariff. These results suggest that incorporating subgroup-specific HU in cost-utility analyses might provide more insight for informed decision-making.},
  author       = {Ahmad Kiadaliri, Aliasghar and Gerdtham, Ulf and Eliasson, Björn and Gudbjörnsdottir, Soffia and Svensson, Ann-Marie and Steen Carlsson, Katarina},
  issn         = {1660-4601},
  language     = {eng},
  number       = {5},
  pages        = {4939--4952},
  publisher    = {Multidisciplinary Digital Publishing Institute (MDPI)},
  series       = {International Journal of Environmental Research and Public Health},
  title        = {Health utilities of type 2 diabetes-related complications: a cross-sectional study in sweden.},
  url          = {http://dx.doi.org/10.3390/ijerph110504939},
  volume       = {11},
  year         = {2014},
}