Apolipoprotein E Genotype and the Diagnostic Accuracy of Cerebrospinal Fluid Biomarkers for Alzheimer Disease.
(2014) In JAMA Psychiatry 71(10). p.1183-1191- Abstract
- Several studies suggest that the apolipoprotein E (APOE) ε4 allele modulates cerebrospinal fluid (CSF) levels of β-amyloid 42 (Aβ42). Whether this effect is secondary to the association of the APOE ε4 allele with cortical Aβ deposition or whether APOE ε4 directly influences CSF levels of Aβ42 independently of Aβ pathology remains unknown.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4613785
- author
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- JAMA Psychiatry
- volume
- 71
- issue
- 10
- pages
- 1183 - 1191
- publisher
- American Medical Association
- external identifiers
-
- pmid:25162367
- wos:000342900200013
- scopus:84907805707
- pmid:25162367
- ISSN
- 2168-6238
- DOI
- 10.1001/jamapsychiatry.2014.1060
- language
- English
- LU publication?
- yes
- id
- eb4a85e8-1f5b-4faf-8515-e37adfd34fc7 (old id 4613785)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25162367?dopt=Abstract
- date added to LUP
- 2016-04-01 10:20:30
- date last changed
- 2022-02-10 01:10:01
@article{eb4a85e8-1f5b-4faf-8515-e37adfd34fc7, abstract = {{Several studies suggest that the apolipoprotein E (APOE) ε4 allele modulates cerebrospinal fluid (CSF) levels of β-amyloid 42 (Aβ42). Whether this effect is secondary to the association of the APOE ε4 allele with cortical Aβ deposition or whether APOE ε4 directly influences CSF levels of Aβ42 independently of Aβ pathology remains unknown.}}, author = {{Lautner, Ronald and Palmqvist, Sebastian and Mattsson, Niklas and Andreasson, Ulf and Wallin, Anders and Pålsson, Erik and Jakobsson, Joel and Herukka, Sanna-Kaisa and Owenius, Rikard and Olsson, Bob and Hampel, Harald and Rujescu, Dan and Ewers, Michael and Landén, Mikael and Minthon, Lennart and Blennow, Kaj and Zetterberg, Henrik and Hansson, Oskar}}, issn = {{2168-6238}}, language = {{eng}}, number = {{10}}, pages = {{1183--1191}}, publisher = {{American Medical Association}}, series = {{JAMA Psychiatry}}, title = {{Apolipoprotein E Genotype and the Diagnostic Accuracy of Cerebrospinal Fluid Biomarkers for Alzheimer Disease.}}, url = {{https://lup.lub.lu.se/search/files/1764940/8056196.pdf}}, doi = {{10.1001/jamapsychiatry.2014.1060}}, volume = {{71}}, year = {{2014}}, }