Advanced

Association between sucrose intake and acute coronary event risk and effect modification by lifestyle factors : Malmö Diet and Cancer Cohort Study

Warfa, K.; Drake, I. LU ; Wallström, P. LU ; Engström, G. LU and Sonestedt, E. LU (2016) In British Journal of Nutrition 116(9). p.1611-1620
Abstract

Previous studies have suggested that a high intake of sugar-sweetened beverages is positively associated with the risk of a coronary event. However, a few studies have examined the association between sucrose (the most common extrinsic sugar in Sweden) and incident coronary events. The objective of the present study was to examine the associations between sucrose intake and coronary event risk and to determine whether these associations are specific to certain subgroups of the population (i.e. according to physical activity, obesity status, educational level, alcohol consumption, smoking habits, intake of fat and intake of fruits and vegetables). We performed a prospective analysis on 26 190 individuals (62 % women) free from diabetes... (More)

Previous studies have suggested that a high intake of sugar-sweetened beverages is positively associated with the risk of a coronary event. However, a few studies have examined the association between sucrose (the most common extrinsic sugar in Sweden) and incident coronary events. The objective of the present study was to examine the associations between sucrose intake and coronary event risk and to determine whether these associations are specific to certain subgroups of the population (i.e. according to physical activity, obesity status, educational level, alcohol consumption, smoking habits, intake of fat and intake of fruits and vegetables). We performed a prospective analysis on 26 190 individuals (62 % women) free from diabetes and without a history of CVD from the Swedish population-based Malmö Diet and Cancer cohort. Over an average of 17 years of follow-up (457 131 person-years), 2493 incident cases of coronary events were identified. Sucrose intake was obtained from an interview-based diet history method, including 7-d records of prepared meals and cold beverages and a 168-item diet questionnaire covering other foods. Participants who consumed >15 % of their energy intake (E%) from sucrose showed a 37 (95 % CI 13, 66) % increased risk of a coronary event compared with the lowest sucrose consumers (<5 E%) after adjusting for potential confounders. The association was not modified by the selected lifestyle factors. The results indicated that sucrose consumption higher than 15 E% (5 % of this population) is associated with an increased risk of a coronary event.

(Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
CVD, Effect modification, Risk factors, Sucrose
in
British Journal of Nutrition
volume
116
issue
9
pages
1611 - 1620
publisher
Cambridge University Press
external identifiers
  • scopus:84992401798
  • wos:000388352600014
ISSN
0007-1145
DOI
10.1017/S0007114516003561
language
English
LU publication?
yes
id
47e2d1bc-8c76-4497-b0b6-9389ee74cce2
date added to LUP
2016-11-09 08:32:45
date last changed
2017-09-18 11:29:48
@article{47e2d1bc-8c76-4497-b0b6-9389ee74cce2,
  abstract     = {<p>Previous studies have suggested that a high intake of sugar-sweetened beverages is positively associated with the risk of a coronary event. However, a few studies have examined the association between sucrose (the most common extrinsic sugar in Sweden) and incident coronary events. The objective of the present study was to examine the associations between sucrose intake and coronary event risk and to determine whether these associations are specific to certain subgroups of the population (i.e. according to physical activity, obesity status, educational level, alcohol consumption, smoking habits, intake of fat and intake of fruits and vegetables). We performed a prospective analysis on 26 190 individuals (62 % women) free from diabetes and without a history of CVD from the Swedish population-based Malmö Diet and Cancer cohort. Over an average of 17 years of follow-up (457 131 person-years), 2493 incident cases of coronary events were identified. Sucrose intake was obtained from an interview-based diet history method, including 7-d records of prepared meals and cold beverages and a 168-item diet questionnaire covering other foods. Participants who consumed &gt;15 % of their energy intake (E%) from sucrose showed a 37 (95 % CI 13, 66) % increased risk of a coronary event compared with the lowest sucrose consumers (&lt;5 E%) after adjusting for potential confounders. The association was not modified by the selected lifestyle factors. The results indicated that sucrose consumption higher than 15 E% (5 % of this population) is associated with an increased risk of a coronary event.</p>},
  author       = {Warfa, K. and Drake, I. and Wallström, P. and Engström, G. and Sonestedt, E.},
  issn         = {0007-1145},
  keyword      = {CVD,Effect modification,Risk factors,Sucrose},
  language     = {eng},
  number       = {9},
  pages        = {1611--1620},
  publisher    = {Cambridge University Press},
  series       = {British Journal of Nutrition},
  title        = {Association between sucrose intake and acute coronary event risk and effect modification by lifestyle factors : Malmö Diet and Cancer Cohort Study},
  url          = {http://dx.doi.org/10.1017/S0007114516003561},
  volume       = {116},
  year         = {2016},
}