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A Novel System for Source Characterization and Controlled Human Exposure to Nanoparticle Aggregates Generated During Gas–Metal Arc Welding

Isaxon, Christina LU ; Dierschke, Katrin LU ; Pagels, Joakim LU ; Löndahl, Jakob LU ; Gudmundsson, Anders LU ; Hagerman, Inger; Berglund, Margareta; Wierzbicka, Aneta LU ; Assarsson, Eva LU and Andersson, Ulla B LU , et al. (2013) In Aerosol Science and Technology 47(1). p.52-59
Abstract (Swedish)
Abstract in Undetermined

The aim of this study was to achieve a method to perform detailed characterization and human exposure studies of nanosized and nanostructured aerosol particles. The source chosen was mild steel, active gas, arc welding fume. The setup consisted of a generation chamber, where welding can be performed, connected to an airtight stainless steel 22 m(3) exposure chamber. Instrumentation, consisting of a tapered element oscillating microbalance, a scanning mobility particle sizer, and a sampler for electron microscopy and particle-induced X-ray emission analysis was connected to the stainless steel chamber. The feasibility of the system for human exposure studies was evaluated by exposing 31 human... (More)
Abstract in Undetermined

The aim of this study was to achieve a method to perform detailed characterization and human exposure studies of nanosized and nanostructured aerosol particles. The source chosen was mild steel, active gas, arc welding fume. The setup consisted of a generation chamber, where welding can be performed, connected to an airtight stainless steel 22 m(3) exposure chamber. Instrumentation, consisting of a tapered element oscillating microbalance, a scanning mobility particle sizer, and a sampler for electron microscopy and particle-induced X-ray emission analysis was connected to the stainless steel chamber. The feasibility of the system for human exposure studies was evaluated by exposing 31 human volunteers, in groups of three, to a test aerosol containing 1 mg/m(3) welding fumes and to conditioned, filtered air. The results show that an aerosol that accurately represents dilute welding fume exposures that occur in workplaces can be produced in a controlled manner, and that the experimental setup can be used for 6 h, double-blind, exposures of human subjects. Particle mass concentration levels could be varied from <5 mu g/m(3) to more than 1000 mu g/m(3). Fumes from metal active gas welding showed a unimodal size distribution with a mean mobility diameter of 160 nm, transmission electron microscopy showed aggregates with a clearly nanosized structure. (Less)
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Contribution to journal
publication status
published
subject
in
Aerosol Science and Technology
volume
47
issue
1
pages
52 - 59
publisher
Taylor & Francis
external identifiers
  • wos:000309965000007
  • scopus:84867164104
ISSN
1521-7388
DOI
10.1080/02786826.2012.724733
project
MERGE
language
English
LU publication?
yes
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4d929004-d00e-48c2-83ab-746b97adacea (old id 1973392)
date added to LUP
2011-06-01 10:03:42
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2019-06-25 01:25:05
@article{4d929004-d00e-48c2-83ab-746b97adacea,
  abstract     = {<b>Abstract in Undetermined</b><br/><br>
The aim of this study was to achieve a method to perform detailed characterization and human exposure studies of nanosized and nanostructured aerosol particles. The source chosen was mild steel, active gas, arc welding fume. The setup consisted of a generation chamber, where welding can be performed, connected to an airtight stainless steel 22 m(3) exposure chamber. Instrumentation, consisting of a tapered element oscillating microbalance, a scanning mobility particle sizer, and a sampler for electron microscopy and particle-induced X-ray emission analysis was connected to the stainless steel chamber. The feasibility of the system for human exposure studies was evaluated by exposing 31 human volunteers, in groups of three, to a test aerosol containing 1 mg/m(3) welding fumes and to conditioned, filtered air. The results show that an aerosol that accurately represents dilute welding fume exposures that occur in workplaces can be produced in a controlled manner, and that the experimental setup can be used for 6 h, double-blind, exposures of human subjects. Particle mass concentration levels could be varied from &lt;5 mu g/m(3) to more than 1000 mu g/m(3). Fumes from metal active gas welding showed a unimodal size distribution with a mean mobility diameter of 160 nm, transmission electron microscopy showed aggregates with a clearly nanosized structure.},
  author       = {Isaxon, Christina and Dierschke, Katrin and Pagels, Joakim and Löndahl, Jakob and Gudmundsson, Anders and Hagerman, Inger and Berglund, Margareta and Wierzbicka, Aneta and Assarsson, Eva and Andersson, Ulla B and Jönsson, Bo A and Nielsen, Jörn and Bohgard, Mats},
  issn         = {1521-7388},
  language     = {eng},
  number       = {1},
  pages        = {52--59},
  publisher    = {Taylor & Francis},
  series       = {Aerosol Science and Technology},
  title        = {A Novel System for Source Characterization and Controlled Human Exposure to Nanoparticle Aggregates Generated During Gas–Metal Arc Welding},
  url          = {http://dx.doi.org/10.1080/02786826.2012.724733},
  volume       = {47},
  year         = {2013},
}