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Fermentation of dietary fibre in the intestinal tract : comparison between man and rat

Nyman, M LU ; Asp, N G LU ; Cummings, J and Wiggins, H (1986) In British Journal of Nutrition 55(3). p.96-487
Abstract

1. The breakdown and faecal bulking capacity of dietary fibre preparations from wheat bran, apple, cabbage, carrot, and guar gum were compared in man and rat. 2. The degradation of the fibre showed good correlation between man and rat (r 0.99, regression coefficient 0.86). Wheat bran was the least well-digested, 66 and 59% of the neutral sugars being excreted in faeces of man and rat respectively. The breakdown of the fibre in apple, cabbage, carrot and guar gum was more complete and 4-29% of the neutral sugars were recovered in faeces. 3. The main dietary fibre constituents in each preparation were degraded to a similar extent in man and rat. The main dietary fibre constituents of apple, carrot, cabbage and guar gum were almost... (More)

1. The breakdown and faecal bulking capacity of dietary fibre preparations from wheat bran, apple, cabbage, carrot, and guar gum were compared in man and rat. 2. The degradation of the fibre showed good correlation between man and rat (r 0.99, regression coefficient 0.86). Wheat bran was the least well-digested, 66 and 59% of the neutral sugars being excreted in faeces of man and rat respectively. The breakdown of the fibre in apple, cabbage, carrot and guar gum was more complete and 4-29% of the neutral sugars were recovered in faeces. 3. The main dietary fibre constituents in each preparation were degraded to a similar extent in man and rat. The main dietary fibre constituents of apple, carrot, cabbage and guar gum were almost completely degraded. Of the xylose in wheat bran 45% (man) and 48% (rat) were recovered in faeces. However, the percentage excretion of glucose and arabinose from bran was higher in man. 4. A faecal glucan other than cellulose was identified in human faeces after guar gum, and has been provisionally identified as starch. No such glucan occurred in rat faeces. 5. A good correlation between the faecal bulking capacity in man and rat was seen (r 0.97, regression coefficient 0.56). Wheat bran had the best bulking capacity, while that of apple, cabbage, carrot and guar gum was less pronounced. Faecal bulking was inversely related to the amount of fibre which was water-soluble in each preparation. 6. It is concluded that this rat experimental model is useful for the prediction of fermentative breakdown and bulking capacity of dietary fibre in man. However, more comparative studies are needed to evaluate animal experiments regarding other physiological effects of dietary fibre.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adult, Animals, Carbohydrate Metabolism, Dietary Fiber/analysis, Fermentation, Humans, Intestines/metabolism, Lignin/metabolism, Male, Rats/metabolism, Uronic Acids/metabolism
in
British Journal of Nutrition
volume
55
issue
3
pages
10 pages
publisher
Cambridge University Press
external identifiers
  • pmid:2823868
  • scopus:0022471008
ISSN
0007-1145
DOI
10.1079/bjn19860056
language
English
LU publication?
yes
id
58755084-0280-4eb5-8a55-c3d90e509d67
date added to LUP
2018-10-16 17:51:51
date last changed
2024-01-15 04:12:07
@article{58755084-0280-4eb5-8a55-c3d90e509d67,
  abstract     = {{<p>1. The breakdown and faecal bulking capacity of dietary fibre preparations from wheat bran, apple, cabbage, carrot, and guar gum were compared in man and rat. 2. The degradation of the fibre showed good correlation between man and rat (r 0.99, regression coefficient 0.86). Wheat bran was the least well-digested, 66 and 59% of the neutral sugars being excreted in faeces of man and rat respectively. The breakdown of the fibre in apple, cabbage, carrot and guar gum was more complete and 4-29% of the neutral sugars were recovered in faeces. 3. The main dietary fibre constituents in each preparation were degraded to a similar extent in man and rat. The main dietary fibre constituents of apple, carrot, cabbage and guar gum were almost completely degraded. Of the xylose in wheat bran 45% (man) and 48% (rat) were recovered in faeces. However, the percentage excretion of glucose and arabinose from bran was higher in man. 4. A faecal glucan other than cellulose was identified in human faeces after guar gum, and has been provisionally identified as starch. No such glucan occurred in rat faeces. 5. A good correlation between the faecal bulking capacity in man and rat was seen (r 0.97, regression coefficient 0.56). Wheat bran had the best bulking capacity, while that of apple, cabbage, carrot and guar gum was less pronounced. Faecal bulking was inversely related to the amount of fibre which was water-soluble in each preparation. 6. It is concluded that this rat experimental model is useful for the prediction of fermentative breakdown and bulking capacity of dietary fibre in man. However, more comparative studies are needed to evaluate animal experiments regarding other physiological effects of dietary fibre.</p>}},
  author       = {{Nyman, M and Asp, N G and Cummings, J and Wiggins, H}},
  issn         = {{0007-1145}},
  keywords     = {{Adult; Animals; Carbohydrate Metabolism; Dietary Fiber/analysis; Fermentation; Humans; Intestines/metabolism; Lignin/metabolism; Male; Rats/metabolism; Uronic Acids/metabolism}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{96--487}},
  publisher    = {{Cambridge University Press}},
  series       = {{British Journal of Nutrition}},
  title        = {{Fermentation of dietary fibre in the intestinal tract : comparison between man and rat}},
  url          = {{http://dx.doi.org/10.1079/bjn19860056}},
  doi          = {{10.1079/bjn19860056}},
  volume       = {{55}},
  year         = {{1986}},
}