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Oesophageal dysmotility, delayed gastric emptying and gastrointestinal symptoms in patients with diabetes mellitus.

Borg, Julia LU ; Melander, Olle LU ; Sundkvist, Göran LU ; Olsson, Rolf LU ; Thorsson, Ola LU ; Ekberg, Olle LU and Ohlsson, Bodil LU (2007) In Diabetic Medicine 24(11). p.1235-1239
Abstract
Aims Gastroparesis is a common gastrointestinal complication in diabetes mellitus, whereas dysfunction in the other gastrointestinal organs has been less thoroughly investigated. Furthermore, it is not known whether there is any relationship between motility and dysmotility between these organs. The aim of this study was to examine whether diabetic patients with gastrointestinal symptoms also have motility disturbances in the oesophagus and stomach and, if so, whether there are any associations between these disturbances. Methods Thirty-one patients with diabetes mellitus who complained of gastrointestinal symptoms were asked to complete a questionnaire about their symptoms. They were further investigated with oesophageal manometry and... (More)
Aims Gastroparesis is a common gastrointestinal complication in diabetes mellitus, whereas dysfunction in the other gastrointestinal organs has been less thoroughly investigated. Furthermore, it is not known whether there is any relationship between motility and dysmotility between these organs. The aim of this study was to examine whether diabetic patients with gastrointestinal symptoms also have motility disturbances in the oesophagus and stomach and, if so, whether there are any associations between these disturbances. Methods Thirty-one patients with diabetes mellitus who complained of gastrointestinal symptoms were asked to complete a questionnaire about their symptoms. They were further investigated with oesophageal manometry and gastric emptying scintigraphy. Results Fifty-eight per cent of the patients had abnormal oesophageal function, and 68% had delayed gastric emptying. Abdominal fullness was the only symptom that related to any dysfunction, and it was associated with delayed gastric emptying (P = 0.02). We did not find any relationship in motility or dysmotility between the oesophagus and the stomach. Conclusion Oesophageal dysmotility, as well as gastroparesis, are common in patients with diabetes who have gastrointestinal symptoms. It is important to investigate these patients further, to be able to reach an accurate diagnosis and instigate appropriate treatment. Our findings indicate that the oesophagus and the stomach function as separate organs and that pathology in one does not necessarily mean pathology in the other. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
oesophageal dysmotility, mellitus, gastroparesis, diabetes, gastrointestinal symptoms, gastrointestinal dysmotility
in
Diabetic Medicine
volume
24
issue
11
pages
1235 - 1239
publisher
Wiley-Blackwell
external identifiers
  • wos:000250297500009
  • scopus:35448991773
ISSN
1464-5491
DOI
10.1111/j.1464-5491.2007.02236.x
language
English
LU publication?
yes
id
433ed4a4-9844-41c6-916a-ac391b840838 (old id 606592)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17725632&dopt=Abstract
date added to LUP
2007-12-10 10:10:43
date last changed
2017-11-05 04:33:48
@article{433ed4a4-9844-41c6-916a-ac391b840838,
  abstract     = {Aims Gastroparesis is a common gastrointestinal complication in diabetes mellitus, whereas dysfunction in the other gastrointestinal organs has been less thoroughly investigated. Furthermore, it is not known whether there is any relationship between motility and dysmotility between these organs. The aim of this study was to examine whether diabetic patients with gastrointestinal symptoms also have motility disturbances in the oesophagus and stomach and, if so, whether there are any associations between these disturbances. Methods Thirty-one patients with diabetes mellitus who complained of gastrointestinal symptoms were asked to complete a questionnaire about their symptoms. They were further investigated with oesophageal manometry and gastric emptying scintigraphy. Results Fifty-eight per cent of the patients had abnormal oesophageal function, and 68% had delayed gastric emptying. Abdominal fullness was the only symptom that related to any dysfunction, and it was associated with delayed gastric emptying (P = 0.02). We did not find any relationship in motility or dysmotility between the oesophagus and the stomach. Conclusion Oesophageal dysmotility, as well as gastroparesis, are common in patients with diabetes who have gastrointestinal symptoms. It is important to investigate these patients further, to be able to reach an accurate diagnosis and instigate appropriate treatment. Our findings indicate that the oesophagus and the stomach function as separate organs and that pathology in one does not necessarily mean pathology in the other.},
  author       = {Borg, Julia and Melander, Olle and Sundkvist, Göran and Olsson, Rolf and Thorsson, Ola and Ekberg, Olle and Ohlsson, Bodil},
  issn         = {1464-5491},
  keyword      = {oesophageal dysmotility,mellitus,gastroparesis,diabetes,gastrointestinal symptoms,gastrointestinal dysmotility},
  language     = {eng},
  number       = {11},
  pages        = {1235--1239},
  publisher    = {Wiley-Blackwell},
  series       = {Diabetic Medicine},
  title        = {Oesophageal dysmotility, delayed gastric emptying and gastrointestinal symptoms in patients with diabetes mellitus.},
  url          = {http://dx.doi.org/10.1111/j.1464-5491.2007.02236.x},
  volume       = {24},
  year         = {2007},
}