The new cell irradiation facility at the Lund nuclear probe
(2007) 10th International Conference on Nuclear Microprobe Technology and Applications and 2nd International Workshop on Proton Beam Writing In Nuclear Instruments & Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms 260(1). p.91-96- Abstract
- The CELLION project is directed towards the studies on cellular response to targeted single ions. This paper gives an account of the modifications made at the Lund sub-micron beam line in order to create a Single Ion Hit Facility for biological applications within the CELLION project. The most relevant new feature is the specially developed software used to locate the cells. A program for cell recognition and localization that gives the coordinates of the centre of the cells has been designed. The recognition is made online. A picture taken by a microscope is used as input parameter for the recognition program. Using V79 Chinese hamster cells, the recognition procedure can be done in less than 0.5 s for a picture size of 800 x 600 pixels... (More)
- The CELLION project is directed towards the studies on cellular response to targeted single ions. This paper gives an account of the modifications made at the Lund sub-micron beam line in order to create a Single Ion Hit Facility for biological applications within the CELLION project. The most relevant new feature is the specially developed software used to locate the cells. A program for cell recognition and localization that gives the coordinates of the centre of the cells has been designed. The recognition is made online. A picture taken by a microscope is used as input parameter for the recognition program. Using V79 Chinese hamster cells, the recognition procedure can be done in less than 0.5 s for a picture size of 800 x 600 pixels with approximately 96% efficiency. This paper also reports target accuracy test results and the first non-targeted irradiation procedure performed at the Lund sub-micron beam line. (c) 2007 Elsevier B.V. All rights reserved. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/647975
- author
- Arteaga, Natalia
LU
; Pallon, Jan
LU
; Gram, Magnus
LU
; Auzelyte, Vaida LU ; Elfman, Mikael LU ; Kristiansson, Per LU ; Malmqvist, Klas LU ; Nilsson, Christer LU and Wegdén, Marie LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- irradiation, single ions, cell, CELLION
- in
- Nuclear Instruments & Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms
- volume
- 260
- issue
- 1
- pages
- 91 - 96
- publisher
- Elsevier
- conference name
- 10th International Conference on Nuclear Microprobe Technology and Applications and 2nd International Workshop on Proton Beam Writing
- conference location
- Singapore
- conference dates
- 2006-07-09 - 2006-07-14
- external identifiers
-
- wos:000248264900018
- scopus:34249882436
- ISSN
- 0168-583X
- DOI
- 10.1016/j.nimb.2007.01.255
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Nuclear Physics (Faculty of Technology) (011013007), Division of Infection Medicine (BMC) (013024020)
- id
- f72bfcd6-e5aa-41e7-9a7d-35ddc5cd5a06 (old id 647975)
- date added to LUP
- 2016-04-01 15:33:24
- date last changed
- 2022-03-22 05:01:16
@article{f72bfcd6-e5aa-41e7-9a7d-35ddc5cd5a06, abstract = {{The CELLION project is directed towards the studies on cellular response to targeted single ions. This paper gives an account of the modifications made at the Lund sub-micron beam line in order to create a Single Ion Hit Facility for biological applications within the CELLION project. The most relevant new feature is the specially developed software used to locate the cells. A program for cell recognition and localization that gives the coordinates of the centre of the cells has been designed. The recognition is made online. A picture taken by a microscope is used as input parameter for the recognition program. Using V79 Chinese hamster cells, the recognition procedure can be done in less than 0.5 s for a picture size of 800 x 600 pixels with approximately 96% efficiency. This paper also reports target accuracy test results and the first non-targeted irradiation procedure performed at the Lund sub-micron beam line. (c) 2007 Elsevier B.V. All rights reserved.}}, author = {{Arteaga, Natalia and Pallon, Jan and Gram, Magnus and Auzelyte, Vaida and Elfman, Mikael and Kristiansson, Per and Malmqvist, Klas and Nilsson, Christer and Wegdén, Marie}}, issn = {{0168-583X}}, keywords = {{irradiation; single ions; cell; CELLION}}, language = {{eng}}, number = {{1}}, pages = {{91--96}}, publisher = {{Elsevier}}, series = {{Nuclear Instruments & Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms}}, title = {{The new cell irradiation facility at the Lund nuclear probe}}, url = {{http://dx.doi.org/10.1016/j.nimb.2007.01.255}}, doi = {{10.1016/j.nimb.2007.01.255}}, volume = {{260}}, year = {{2007}}, }