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Apgar score predicts short-term outcome in infants born at 25 gestational weeks

Forsblad, Kristina LU ; Källén, Karin LU ; Marsal, Karel LU and Hellström-Westas, Lena LU (2007) In Acta Paediatrica 96(2). p.166-171
Abstract
Aim: To identify early predictors of outcome in infants born at 25 gestational weeks. Material and Methods: Data from a regional perinatal database (time-period 1995-2001, total n = 108 000 births) were used. Apgar scores were available in 92 preterm infants, born at 25 + 0 to 25 + 6 gestational weeks, and analyzed in relation to short-term outcome (180-day survival with, or without, severe brain damage defined as intraventricular hemorrhage grade 3-4 or cystic periventricular leukomalacia). Based on multiple logistic regression analyses we constructed graphs of the estimated chance of survival. Results: Apgar scores at 1, 5 and 10 min correlated with survival without severe brain damage (p = 0.02, 0.006 and 0.006, respectively). Survival... (More)
Aim: To identify early predictors of outcome in infants born at 25 gestational weeks. Material and Methods: Data from a regional perinatal database (time-period 1995-2001, total n = 108 000 births) were used. Apgar scores were available in 92 preterm infants, born at 25 + 0 to 25 + 6 gestational weeks, and analyzed in relation to short-term outcome (180-day survival with, or without, severe brain damage defined as intraventricular hemorrhage grade 3-4 or cystic periventricular leukomalacia). Based on multiple logistic regression analyses we constructed graphs of the estimated chance of survival. Results: Apgar scores at 1, 5 and 10 min correlated with survival without severe brain damage (p = 0.02, 0.006 and 0.006, respectively). Survival without severe brain damage was higher in singleton than in multiple births (p = 0.03); there was no association with infant gender or mode of delivery. The strongest model for prediction of survival without severe brain damage was based on 5-min Apgar score and the Clinical Risk Index for Babies (CRIB), (p < 0.001). Conclusion: Apgar score predicts short-term outcome in extremely preterm infants at 25 gestational weeks. The precision for prediction of outcome increases when Apgar score is combined with CRIB. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
preterm, outcome, apgar score, newborn, prognosis
in
Acta Paediatrica
volume
96
issue
2
pages
166 - 171
publisher
Wiley-Blackwell Publishing Ltd
external identifiers
  • wos:000243993800006
  • scopus:33847184927
ISSN
0803-5253
DOI
10.1111/j.1651-2227.2007.00099.x
language
English
LU publication?
yes
id
c580fdd9-5aee-4178-8d67-57a8837c2725 (old id 675376)
date added to LUP
2008-07-31 14:23:21
date last changed
2017-02-26 04:07:42
@article{c580fdd9-5aee-4178-8d67-57a8837c2725,
  abstract     = {Aim: To identify early predictors of outcome in infants born at 25 gestational weeks. Material and Methods: Data from a regional perinatal database (time-period 1995-2001, total n = 108 000 births) were used. Apgar scores were available in 92 preterm infants, born at 25 + 0 to 25 + 6 gestational weeks, and analyzed in relation to short-term outcome (180-day survival with, or without, severe brain damage defined as intraventricular hemorrhage grade 3-4 or cystic periventricular leukomalacia). Based on multiple logistic regression analyses we constructed graphs of the estimated chance of survival. Results: Apgar scores at 1, 5 and 10 min correlated with survival without severe brain damage (p = 0.02, 0.006 and 0.006, respectively). Survival without severe brain damage was higher in singleton than in multiple births (p = 0.03); there was no association with infant gender or mode of delivery. The strongest model for prediction of survival without severe brain damage was based on 5-min Apgar score and the Clinical Risk Index for Babies (CRIB), (p &lt; 0.001). Conclusion: Apgar score predicts short-term outcome in extremely preterm infants at 25 gestational weeks. The precision for prediction of outcome increases when Apgar score is combined with CRIB.},
  author       = {Forsblad, Kristina and Källén, Karin and Marsal, Karel and Hellström-Westas, Lena},
  issn         = {0803-5253},
  keyword      = {preterm,outcome,apgar score,newborn,prognosis},
  language     = {eng},
  number       = {2},
  pages        = {166--171},
  publisher    = {Wiley-Blackwell Publishing Ltd},
  series       = {Acta Paediatrica},
  title        = {Apgar score predicts short-term outcome in infants born at 25 gestational weeks},
  url          = {http://dx.doi.org/10.1111/j.1651-2227.2007.00099.x},
  volume       = {96},
  year         = {2007},
}