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Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a six months exercise intervention.

Rönn, Tina LU ; Volkov, Petr LU ; Tornberg, Åsa LU orcid ; Elgzyri, Targ LU ; Hansson, Ola LU orcid ; Eriksson, Karl-Fredrik LU ; Groop, Leif LU and Ling, Charlotte LU orcid (2014) In Acta Physiologica 211(1). p.188-200
Abstract
Adipose tissue has an important function in total energy homeostasis and its dysregulation may contribute to life-style related diseases such as type 2 diabetes, cancer and cardiovascular diseases. The aim of this study was to investigate genome-wide mRNA expression in adipose tissue in healthy men before and after an exercise intervention to identify genes or pathways that mediate the beneficial effect of regular exercise. We also investigated the difference in adipose tissue mRNA expression between individuals with or without a family history of type 2 diabetes.
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Physiologica
volume
211
issue
1
pages
188 - 200
publisher
Wiley-Blackwell
external identifiers
  • pmid:24495239
  • wos:000334488200020
  • scopus:84899047144
  • pmid:24495239
ISSN
1748-1716
DOI
10.1111/apha.12247
project
Fysik aktivitet, träning och kost vid typ 2 diabetes
language
English
LU publication?
yes
id
68a857e0-d468-4d97-aed0-5307bfb907c5 (old id 4335643)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24495239?dopt=Abstract
date added to LUP
2016-04-01 10:25:14
date last changed
2024-02-21 16:00:19
@article{68a857e0-d468-4d97-aed0-5307bfb907c5,
  abstract     = {{Adipose tissue has an important function in total energy homeostasis and its dysregulation may contribute to life-style related diseases such as type 2 diabetes, cancer and cardiovascular diseases. The aim of this study was to investigate genome-wide mRNA expression in adipose tissue in healthy men before and after an exercise intervention to identify genes or pathways that mediate the beneficial effect of regular exercise. We also investigated the difference in adipose tissue mRNA expression between individuals with or without a family history of type 2 diabetes.}},
  author       = {{Rönn, Tina and Volkov, Petr and Tornberg, Åsa and Elgzyri, Targ and Hansson, Ola and Eriksson, Karl-Fredrik and Groop, Leif and Ling, Charlotte}},
  issn         = {{1748-1716}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{188--200}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Physiologica}},
  title        = {{Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a six months exercise intervention.}},
  url          = {{http://dx.doi.org/10.1111/apha.12247}},
  doi          = {{10.1111/apha.12247}},
  volume       = {{211}},
  year         = {{2014}},
}