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Increased plasma prolactin levels in a group of men with breast cancer - a preliminary study

Olsson, H. LU ; Alm, P. LU ; Aspegren, K.; Gullberg, B. LU ; Jonsson, P. E. and Ranstam, J. (1990) In Anticancer research 10(1). p.59-62
Abstract

Gonadal and hypophyseal hormones were investigated in 15 males with breast cancer and 15 tumour referents, on average 1 month postoperatively. Plasma prolactin was found to be significantly more often elevated in men with breast cancer compared with referents (p <0.005). Another group of men with breast cancer disclosed a tendency for lower S-FSH levels compared with the referents (p <0.01). No significant difference was seen between cases and referents regarding S-LH, p-estradiol or p-testosterone. The size of the primary breast tumour was correlated with a higher prolactin level. The findings lend support to a theory implicating prolactin and possibly prolactinomas as a risk factor for the disease in males.

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author
organization
publishing date
type
Contribution to journal
publication status
published
keywords
breast cancer, men, plasma, prolactin
in
Anticancer research
volume
10
issue
1
pages
59 - 62
publisher
International Institute of Cancer Research
external identifiers
  • scopus:0025264065
ISSN
0250-7005
language
English
LU publication?
yes
id
6d0d5920-f0a0-4df9-bf96-de6f1d84753b
date added to LUP
2018-12-19 13:44:03
date last changed
2019-01-06 14:20:43
@article{6d0d5920-f0a0-4df9-bf96-de6f1d84753b,
  abstract     = {<p>Gonadal and hypophyseal hormones were investigated in 15 males with breast cancer and 15 tumour referents, on average 1 month postoperatively. Plasma prolactin was found to be significantly more often elevated in men with breast cancer compared with referents (p &lt;0.005). Another group of men with breast cancer disclosed a tendency for lower S-FSH levels compared with the referents (p &lt;0.01). No significant difference was seen between cases and referents regarding S-LH, p-estradiol or p-testosterone. The size of the primary breast tumour was correlated with a higher prolactin level. The findings lend support to a theory implicating prolactin and possibly prolactinomas as a risk factor for the disease in males.</p>},
  author       = {Olsson, H. and Alm, P. and Aspegren, K. and Gullberg, B. and Jonsson, P. E. and Ranstam, J.},
  issn         = {0250-7005},
  keyword      = {breast cancer,men,plasma,prolactin},
  language     = {eng},
  month        = {01},
  number       = {1},
  pages        = {59--62},
  publisher    = {International Institute of Cancer Research},
  series       = {Anticancer research},
  title        = {Increased plasma prolactin levels in a group of men with breast cancer - a preliminary study},
  volume       = {10},
  year         = {1990},
}