Ilio-femoral calcium score may assist Glasgow Aneurysm Score prediction of long-term survival of low-risk patients after infrarenal EVAR
(2022) In International Angiology 41(4). p.285-291- Abstract
BACKGROUND: The aim of this study is to evaluate if ilio-femoral calcium score (CS) combined with Glasgow Aneurysm Score (GAS) can improve the prediction of long-term survival after EVAR.
METHODS: All the patients who underwent infrarenal endovascular aortic repair (EVAR) for non-ruptured AAA between January 2004 and December 2012 at a tertiary referral center were retrospectively included if the preoperative imaging was of sufficient quality and they had survived for more than 30 days. Preoperative non-contrast enhanced CT were used to measure ilio-femoral calcium score using dedicated postprocessing software. GAS was calculated and patients were divided into low or high GAS by a cutoff of 80.
RESULTS: Two hundred and... (More)
BACKGROUND: The aim of this study is to evaluate if ilio-femoral calcium score (CS) combined with Glasgow Aneurysm Score (GAS) can improve the prediction of long-term survival after EVAR.
METHODS: All the patients who underwent infrarenal endovascular aortic repair (EVAR) for non-ruptured AAA between January 2004 and December 2012 at a tertiary referral center were retrospectively included if the preoperative imaging was of sufficient quality and they had survived for more than 30 days. Preoperative non-contrast enhanced CT were used to measure ilio-femoral calcium score using dedicated postprocessing software. GAS was calculated and patients were divided into low or high GAS by a cutoff of 80.
RESULTS: Two hundred and eighty-eight out of 500 patients were included in the study with no difference in survival compared to excluded patients (P=0.529). Patients were followed-up for a median of 7 (range 4-9) years. GAS correlated positively with ilio-femoral calcium score (r=0.123; P=0.037). One hundred and thirty-five patients (46.9%) had low GAS, and 153 (53.1%) had high GAS. Patients with high GAS had lower survival compared to the ones with low GAS (P≤0.0001). GAS was associated with long-term mortality in a uni- and multivariate regression (P≤0.0001 and P≤0.0001). Ilio-femoral calcium score was significantly associated with mortality in the group with low GAS (P=0.028), but not in the group with high GAS (P=0.297). Significance retained in multivariate regression analysis (P=0.029). Moreover, in the low GAS group, ilio-femoral calcium score was further divided in high and low according to the median. Patients with high calcium score had lower survival compared to the ones with low calcium score (P=0.047).
CONCLUSIONS: Long-term survival in patients who have had infrarenal EVAR can be predicted by the clinically based Glasgow Aneurysm Score. Measuring the ilio-femoral calcium score preoperatively may refine GAS assessment in low-risk patients.
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- author
- Vaccarino, Roberta LU ; Wachtmeister, Melker ; Sun, Jianming ; Bornè, Yan LU ; Resch, Timothy LU ; Sonesson, Björn LU and Dias, Nuno V LU
- organization
- publishing date
- 2022-08
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Aortic Aneurysm, Abdominal/complications, Blood Vessel Prosthesis Implantation/methods, Calcium, Endovascular Procedures/adverse effects, Humans, Retrospective Studies, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome
- in
- International Angiology
- volume
- 41
- issue
- 4
- pages
- 285 - 291
- publisher
- Minerva Medica
- external identifiers
-
- scopus:85135380382
- pmid:35583456
- ISSN
- 1827-1839
- DOI
- 10.23736/S0392-9590.22.04883-0
- language
- English
- LU publication?
- yes
- id
- 70872cdb-0d01-4448-957d-5b43e40788ad
- date added to LUP
- 2022-07-29 23:08:20
- date last changed
- 2024-09-20 03:15:47
@article{70872cdb-0d01-4448-957d-5b43e40788ad, abstract = {{<p>BACKGROUND: The aim of this study is to evaluate if ilio-femoral calcium score (CS) combined with Glasgow Aneurysm Score (GAS) can improve the prediction of long-term survival after EVAR.</p><p>METHODS: All the patients who underwent infrarenal endovascular aortic repair (EVAR) for non-ruptured AAA between January 2004 and December 2012 at a tertiary referral center were retrospectively included if the preoperative imaging was of sufficient quality and they had survived for more than 30 days. Preoperative non-contrast enhanced CT were used to measure ilio-femoral calcium score using dedicated postprocessing software. GAS was calculated and patients were divided into low or high GAS by a cutoff of 80.</p><p>RESULTS: Two hundred and eighty-eight out of 500 patients were included in the study with no difference in survival compared to excluded patients (P=0.529). Patients were followed-up for a median of 7 (range 4-9) years. GAS correlated positively with ilio-femoral calcium score (r=0.123; P=0.037). One hundred and thirty-five patients (46.9%) had low GAS, and 153 (53.1%) had high GAS. Patients with high GAS had lower survival compared to the ones with low GAS (P≤0.0001). GAS was associated with long-term mortality in a uni- and multivariate regression (P≤0.0001 and P≤0.0001). Ilio-femoral calcium score was significantly associated with mortality in the group with low GAS (P=0.028), but not in the group with high GAS (P=0.297). Significance retained in multivariate regression analysis (P=0.029). Moreover, in the low GAS group, ilio-femoral calcium score was further divided in high and low according to the median. Patients with high calcium score had lower survival compared to the ones with low calcium score (P=0.047).</p><p>CONCLUSIONS: Long-term survival in patients who have had infrarenal EVAR can be predicted by the clinically based Glasgow Aneurysm Score. Measuring the ilio-femoral calcium score preoperatively may refine GAS assessment in low-risk patients.</p>}}, author = {{Vaccarino, Roberta and Wachtmeister, Melker and Sun, Jianming and Bornè, Yan and Resch, Timothy and Sonesson, Björn and Dias, Nuno V}}, issn = {{1827-1839}}, keywords = {{Aortic Aneurysm, Abdominal/complications; Blood Vessel Prosthesis Implantation/methods; Calcium; Endovascular Procedures/adverse effects; Humans; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome}}, language = {{eng}}, number = {{4}}, pages = {{285--291}}, publisher = {{Minerva Medica}}, series = {{International Angiology}}, title = {{Ilio-femoral calcium score may assist Glasgow Aneurysm Score prediction of long-term survival of low-risk patients after infrarenal EVAR}}, url = {{http://dx.doi.org/10.23736/S0392-9590.22.04883-0}}, doi = {{10.23736/S0392-9590.22.04883-0}}, volume = {{41}}, year = {{2022}}, }