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Striatal Atrophy in the Behavioural Variant of Frontotemporal Dementia: Correlation with Diagnosis, Negative Symptoms and Disease Severity.

Macfarlane, Matthew D; Jakabek, David; Walterfang, Mark; Vestberg, Susanna LU ; Velakoulis, Dennis; Wilkes, Fiona A; Nilsson, Christer LU ; van Westen, Danielle LU ; Looi, Jeffrey C L and Santillo, Alexander LU (2015) In PLoS ONE 10(6).
Abstract
Behavioural variant frontotemporal dementia (bvFTD) is associated with changes in dorsal striatal parts of the basal ganglia (caudate nucleus and putamen), related to dysfunction in the cortico-striato-thalamic circuits which help mediate executive and motor functions. We aimed to determine whether the size and shape of striatal structures correlated with diagnosis of bvFTD, and measures of clinical severity, behaviour and cognition.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
10
issue
6
publisher
Public Library of Science
external identifiers
  • pmid:26075893
  • wos:000356329900093
  • scopus:84937013097
ISSN
1932-6203
DOI
10.1371/journal.pone.0129692
language
English
LU publication?
yes
id
cbc36451-112b-481d-aebb-508f14216a49 (old id 7486181)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26075893?dopt=Abstract
date added to LUP
2015-07-08 16:11:57
date last changed
2017-11-05 03:56:50
@article{cbc36451-112b-481d-aebb-508f14216a49,
  abstract     = {Behavioural variant frontotemporal dementia (bvFTD) is associated with changes in dorsal striatal parts of the basal ganglia (caudate nucleus and putamen), related to dysfunction in the cortico-striato-thalamic circuits which help mediate executive and motor functions. We aimed to determine whether the size and shape of striatal structures correlated with diagnosis of bvFTD, and measures of clinical severity, behaviour and cognition.},
  articleno    = {e0129692},
  author       = {Macfarlane, Matthew D and Jakabek, David and Walterfang, Mark and Vestberg, Susanna and Velakoulis, Dennis and Wilkes, Fiona A and Nilsson, Christer and van Westen, Danielle and Looi, Jeffrey C L and Santillo, Alexander},
  issn         = {1932-6203},
  language     = {eng},
  number       = {6},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {Striatal Atrophy in the Behavioural Variant of Frontotemporal Dementia: Correlation with Diagnosis, Negative Symptoms and Disease Severity.},
  url          = {http://dx.doi.org/10.1371/journal.pone.0129692},
  volume       = {10},
  year         = {2015},
}