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Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.

Green, Rasmus W; Engblom, Sanna; Baldetorp, Bo LU ; Werner Hartman, Linda LU ; Måsbäck, Anna LU and Bjurberg, Maria LU (2015) In Acta Obstetricia et Gynecologica Scandinavica 94(10). p.1064-1073
Abstract
In early-stage endometrial carcinoma, there is controversy regarding the prognostic value of the flow cytometric variables DNA ploidy (diploid vs. aneuploid) and S-phase fraction. In Sweden, the former is included in national guidelines despite poor scientific support and the latter is not used clinically. This study investigates the prognostic properties of these variables, together with classical histopathological variables, in multivariate analysis in a stringently stratified material.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Obstetricia et Gynecologica Scandinavica
volume
94
issue
10
pages
1064 - 1073
publisher
Wiley-Blackwell
external identifiers
  • pmid:26123703
  • wos:000362511300006
  • scopus:84941660184
ISSN
1600-0412
DOI
10.1111/aogs.12704
language
English
LU publication?
yes
id
e51b4323-b61b-4b38-808a-01c11da9de05 (old id 7751471)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26123703?dopt=Abstract
date added to LUP
2015-08-01 20:51:12
date last changed
2017-10-29 03:07:24
@article{e51b4323-b61b-4b38-808a-01c11da9de05,
  abstract     = {In early-stage endometrial carcinoma, there is controversy regarding the prognostic value of the flow cytometric variables DNA ploidy (diploid vs. aneuploid) and S-phase fraction. In Sweden, the former is included in national guidelines despite poor scientific support and the latter is not used clinically. This study investigates the prognostic properties of these variables, together with classical histopathological variables, in multivariate analysis in a stringently stratified material.},
  author       = {Green, Rasmus W and Engblom, Sanna and Baldetorp, Bo and Werner Hartman, Linda and Måsbäck, Anna and Bjurberg, Maria},
  issn         = {1600-0412},
  language     = {eng},
  number       = {10},
  pages        = {1064--1073},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Obstetricia et Gynecologica Scandinavica},
  title        = {Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.},
  url          = {http://dx.doi.org/10.1111/aogs.12704},
  volume       = {94},
  year         = {2015},
}