Dietary index based on the Food Standards Agency nutrient profiling system and risk of Crohn's disease and ulcerative colitis
(2023) In Alimentary Pharmacology and Therapeutics- Abstract
Background: Nutri-score is now widely available in food packages in Europe. Aim: To study the overall nutritional quality of the diet in relation to risks of Crohn's disease (CD) and ulcerative colitis (UC), in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: We collected dietary data at baseline from validated food frequency questionnaires. We used a dietary index based on the UK Food Standards Agency modified nutrient profiling system (FSAm-NPS-DI) underlying the Nutri-Score label, to measure the nutritional quality of the diet. We estimated the association between FSAm-NPS-DI score, and CD and UC risks using Cox models stratified by centre, sex and age; and adjusted for smoking status, BMI,... (More)
Background: Nutri-score is now widely available in food packages in Europe. Aim: To study the overall nutritional quality of the diet in relation to risks of Crohn's disease (CD) and ulcerative colitis (UC), in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: We collected dietary data at baseline from validated food frequency questionnaires. We used a dietary index based on the UK Food Standards Agency modified nutrient profiling system (FSAm-NPS-DI) underlying the Nutri-Score label, to measure the nutritional quality of the diet. We estimated the association between FSAm-NPS-DI score, and CD and UC risks using Cox models stratified by centre, sex and age; and adjusted for smoking status, BMI, physical activity, energy intake, educational level and alcohol intake. Results: We included 394,255 participants (68.1% women; mean age at recruitment 52.1 years). After a mean follow-up of 13.6 years, there were 184 incident cases of CD and 459 incident cases of UC. Risk of CD was higher in those with a lower nutritional quality, that is higher FSAm-NPS-DI Score (fourth vs. first quartile: aHR: 2.04, 95% CI: 1.24–3.36; p-trend: <0.01). Among items of the FSAm-NPS-DI Score, low intakes of dietary fibre and fruits/vegetables/legumes/nuts were associated with higher risk of CD. Nutritional quality was not associated with risk of UC (fourth vs. first quartile of the FSAm-NPS-DI Score: aHR: 0.91, 95% CI: 0.69–1.21; p-trend: 0.76). Conclusions: A diet with low nutritional quality as measured by the FSAm-NPS-DI Score is associated with a higher risk of CD but not UC.
(Less)
- author
- publishing date
- 2023-12-15
- type
- Contribution to journal
- publication status
- epub
- subject
- keywords
- dietary, EPIC, FSAm-NPS DI score, inflammatory bowel disease, nutri-score
- in
- Alimentary Pharmacology and Therapeutics
- pages
- 11 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:38100159
- scopus:85179951683
- ISSN
- 0269-2813
- DOI
- 10.1111/apt.17835
- language
- English
- LU publication?
- no
- additional info
- Publisher Copyright: © 2023 The Authors. Alimentary Pharmacology & Therapeutics published by John Wiley & Sons Ltd.
- id
- 7c3886de-6330-499c-bbfa-b9dc865d7a1a
- date added to LUP
- 2024-01-09 14:23:35
- date last changed
- 2024-04-24 10:17:35
@article{7c3886de-6330-499c-bbfa-b9dc865d7a1a,
abstract = {{<p>Background: Nutri-score is now widely available in food packages in Europe. Aim: To study the overall nutritional quality of the diet in relation to risks of Crohn's disease (CD) and ulcerative colitis (UC), in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: We collected dietary data at baseline from validated food frequency questionnaires. We used a dietary index based on the UK Food Standards Agency modified nutrient profiling system (FSAm-NPS-DI) underlying the Nutri-Score label, to measure the nutritional quality of the diet. We estimated the association between FSAm-NPS-DI score, and CD and UC risks using Cox models stratified by centre, sex and age; and adjusted for smoking status, BMI, physical activity, energy intake, educational level and alcohol intake. Results: We included 394,255 participants (68.1% women; mean age at recruitment 52.1 years). After a mean follow-up of 13.6 years, there were 184 incident cases of CD and 459 incident cases of UC. Risk of CD was higher in those with a lower nutritional quality, that is higher FSAm-NPS-DI Score (fourth vs. first quartile: aHR: 2.04, 95% CI: 1.24–3.36; p-trend: <0.01). Among items of the FSAm-NPS-DI Score, low intakes of dietary fibre and fruits/vegetables/legumes/nuts were associated with higher risk of CD. Nutritional quality was not associated with risk of UC (fourth vs. first quartile of the FSAm-NPS-DI Score: aHR: 0.91, 95% CI: 0.69–1.21; p-trend: 0.76). Conclusions: A diet with low nutritional quality as measured by the FSAm-NPS-DI Score is associated with a higher risk of CD but not UC.</p>}},
author = {{Meyer, Antoine and Dong, Catherine and Chan, Simon S.M. and Touvier, Mathilde and Julia, Chantal and Huybrechts, Inge and Nicolas, Geneviève and Oldenburg, Bas and Heath, Alicia K. and Tong, Tammy Y.N. and Key, Timothy J. and Tjønneland, Anne and Kyrø, Cecilie and Kaaks, Rudolf and Katzke, Verena A. and Bergman, Manuela M. and Palli, Domenico and Masala, Giovanna and Tumino, Rosario and Sacerdote, Carlotta and Colorado-Yohar, Sandra M. and Sánchez, Maria Jose and Guevara, Marcela and Grip, Olof and Holmgren, Johanna and Cross, Amanda and Karling, Pontus and Hultdin, Johan and Murphy, Neil and Deschasaux-Tanguy, Mélanie and Hercberg, Serge and Galan, Pilar and Mahamat-Saleh, Yahya and Amiot, Aurélien and Gunter, Marc J. and Boutron-Ruault, Marie Christine and Carbonnel, Franck}},
issn = {{0269-2813}},
keywords = {{dietary; EPIC; FSAm-NPS DI score; inflammatory bowel disease; nutri-score}},
language = {{eng}},
month = {{12}},
publisher = {{Wiley-Blackwell}},
series = {{Alimentary Pharmacology and Therapeutics}},
title = {{Dietary index based on the Food Standards Agency nutrient profiling system and risk of Crohn's disease and ulcerative colitis}},
url = {{http://dx.doi.org/10.1111/apt.17835}},
doi = {{10.1111/apt.17835}},
year = {{2023}},
}