A clinical distance measure for evaluating treatment plan quality difference with Pareto fronts in radiotherapy
(2017) In Physics and imaging in radiation oncology 3. p.53-56- Abstract
- We present a clinical distance measure for Pareto front evaluation studies in radiotherapy, which we show strongly correlates (r = 0.74 and 0.90) with clinical plan quality evaluation. For five prostate cases, sub-optimal treatment plans located at a clinical distance value of >0.32 (0.28–0.35) from fronts of Pareto optimal plans, were assessed to be of lower plan quality by our (12) observers (p < .05). In conclusion, the clinical distance measure can be used to determine if the difference between a front and a given plan (or between different fronts) corresponds to a clinically significant plan quality difference.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7e1f2e8d-73bf-453b-990a-a7f59b2b43da
- author
- Petersson, Kristoffer LU ; Kyroudi, Archonteia ; Bourhis, Jean ; Ceberg, Crister LU ; Knoos, Tommy LU ; Bochud, Francois and Möckli, Raphaël
- organization
- publishing date
- 2017-07
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Physics and imaging in radiation oncology
- volume
- 3
- pages
- 53 - 56
- publisher
- Elsevier
- external identifiers
-
- scopus:85070485711
- ISSN
- 2405-6316
- DOI
- 10.1016/j.phro.2017.09.003
- language
- English
- LU publication?
- yes
- id
- 7e1f2e8d-73bf-453b-990a-a7f59b2b43da
- date added to LUP
- 2019-06-18 10:24:21
- date last changed
- 2022-03-16 23:37:21
@article{7e1f2e8d-73bf-453b-990a-a7f59b2b43da, abstract = {{We present a clinical distance measure for Pareto front evaluation studies in radiotherapy, which we show strongly correlates (r = 0.74 and 0.90) with clinical plan quality evaluation. For five prostate cases, sub-optimal treatment plans located at a clinical distance value of >0.32 (0.28–0.35) from fronts of Pareto optimal plans, were assessed to be of lower plan quality by our (12) observers (p < .05). In conclusion, the clinical distance measure can be used to determine if the difference between a front and a given plan (or between different fronts) corresponds to a clinically significant plan quality difference.}}, author = {{Petersson, Kristoffer and Kyroudi, Archonteia and Bourhis, Jean and Ceberg, Crister and Knoos, Tommy and Bochud, Francois and Möckli, Raphaël}}, issn = {{2405-6316}}, language = {{eng}}, pages = {{53--56}}, publisher = {{Elsevier}}, series = {{Physics and imaging in radiation oncology}}, title = {{A clinical distance measure for evaluating treatment plan quality difference with Pareto fronts in radiotherapy}}, url = {{http://dx.doi.org/10.1016/j.phro.2017.09.003}}, doi = {{10.1016/j.phro.2017.09.003}}, volume = {{3}}, year = {{2017}}, }