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Acute Effects of a Spinach Extract Rich in Thylakoids on Satiety: A Randomized Controlled Crossover Trial

Rebello, Candida J.; Chu, Jessica; Beyl, Robbie; Edwall, Dan; Erlanson-Albertsson, Charlotte LU and Greenway, Frank L. (2015) In Journal of the American College of Nutrition 34(6). p.470-477
Abstract
Objective: By retarding fat digestion, thylakoids, the internal photosynthetic membrane system of green plants, promote the release of satiety hormones. This study examined the effect of consuming a single dose of concentrated extract of thylakoids from spinach on satiety, food intake, lipids, and glucose compared to a placebo. Design: Sixty overweight and obese individuals enrolled in a double-blind randomized crossover study consumed the spinach extract or placebo in random order at least a week apart. Blood was drawn for assessments of lipids and glucose before a standard breakfast meal, followed 4 hours later by a 5 g dose of the extract and a standard lunch. Visual analog scales were administered before lunch and at intervals until an... (More)
Objective: By retarding fat digestion, thylakoids, the internal photosynthetic membrane system of green plants, promote the release of satiety hormones. This study examined the effect of consuming a single dose of concentrated extract of thylakoids from spinach on satiety, food intake, lipids, and glucose compared to a placebo. Design: Sixty overweight and obese individuals enrolled in a double-blind randomized crossover study consumed the spinach extract or placebo in random order at least a week apart. Blood was drawn for assessments of lipids and glucose before a standard breakfast meal, followed 4 hours later by a 5 g dose of the extract and a standard lunch. Visual analog scales were administered before lunch and at intervals until an ad libitum pizza dinner served 4 hours later. Two hours after lunch a second blood draw was conducted. Mixed models were used to analyze response changes. Results: Compared to placebo, consuming the spinach extract reduced hunger (p < 0.01) and longing for food over 2 hours (p < 0.01) and increased postprandial plasma glucose concentrations (p < 0.01). There were no differences in plasma lipids and energy intake at dinner, but males showed a trend toward decreased energy intake (p = 0.08). Conclusions: At this dose, the spinach extract containing thylakoids increases satiety over a 2-hour period compared to a placebo. Thylakoid consumption may influence gender-specific food cravings. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
thylakoids, spinach, satiety, food cravings, fat digestion
in
Journal of the American College of Nutrition
volume
34
issue
6
pages
470 - 477
publisher
American College of Nutrition
external identifiers
  • wos:000362555400002
  • scopus:84944154638
ISSN
0731-5724
DOI
10.1080/07315724.2014.1003999
language
English
LU publication?
yes
id
938c3d6c-47c8-4c45-bb8c-db56359d39fb (old id 8195202)
date added to LUP
2015-12-01 07:08:46
date last changed
2017-01-01 05:30:25
@article{938c3d6c-47c8-4c45-bb8c-db56359d39fb,
  abstract     = {Objective: By retarding fat digestion, thylakoids, the internal photosynthetic membrane system of green plants, promote the release of satiety hormones. This study examined the effect of consuming a single dose of concentrated extract of thylakoids from spinach on satiety, food intake, lipids, and glucose compared to a placebo. Design: Sixty overweight and obese individuals enrolled in a double-blind randomized crossover study consumed the spinach extract or placebo in random order at least a week apart. Blood was drawn for assessments of lipids and glucose before a standard breakfast meal, followed 4 hours later by a 5 g dose of the extract and a standard lunch. Visual analog scales were administered before lunch and at intervals until an ad libitum pizza dinner served 4 hours later. Two hours after lunch a second blood draw was conducted. Mixed models were used to analyze response changes. Results: Compared to placebo, consuming the spinach extract reduced hunger (p &lt; 0.01) and longing for food over 2 hours (p &lt; 0.01) and increased postprandial plasma glucose concentrations (p &lt; 0.01). There were no differences in plasma lipids and energy intake at dinner, but males showed a trend toward decreased energy intake (p = 0.08). Conclusions: At this dose, the spinach extract containing thylakoids increases satiety over a 2-hour period compared to a placebo. Thylakoid consumption may influence gender-specific food cravings.},
  author       = {Rebello, Candida J. and Chu, Jessica and Beyl, Robbie and Edwall, Dan and Erlanson-Albertsson, Charlotte and Greenway, Frank L.},
  issn         = {0731-5724},
  keyword      = {thylakoids,spinach,satiety,food cravings,fat digestion},
  language     = {eng},
  number       = {6},
  pages        = {470--477},
  publisher    = {American College of Nutrition},
  series       = {Journal of the American College of Nutrition},
  title        = {Acute Effects of a Spinach Extract Rich in Thylakoids on Satiety: A Randomized Controlled Crossover Trial},
  url          = {http://dx.doi.org/10.1080/07315724.2014.1003999},
  volume       = {34},
  year         = {2015},
}