Acute Effects of a Spinach Extract Rich in Thylakoids on Satiety: A Randomized Controlled Crossover Trial
(2015) In Journal of the American College of Nutrition 34(6). p.470-477- Abstract
- Objective: By retarding fat digestion, thylakoids, the internal photosynthetic membrane system of green plants, promote the release of satiety hormones. This study examined the effect of consuming a single dose of concentrated extract of thylakoids from spinach on satiety, food intake, lipids, and glucose compared to a placebo. Design: Sixty overweight and obese individuals enrolled in a double-blind randomized crossover study consumed the spinach extract or placebo in random order at least a week apart. Blood was drawn for assessments of lipids and glucose before a standard breakfast meal, followed 4 hours later by a 5 g dose of the extract and a standard lunch. Visual analog scales were administered before lunch and at intervals until an... (More)
- Objective: By retarding fat digestion, thylakoids, the internal photosynthetic membrane system of green plants, promote the release of satiety hormones. This study examined the effect of consuming a single dose of concentrated extract of thylakoids from spinach on satiety, food intake, lipids, and glucose compared to a placebo. Design: Sixty overweight and obese individuals enrolled in a double-blind randomized crossover study consumed the spinach extract or placebo in random order at least a week apart. Blood was drawn for assessments of lipids and glucose before a standard breakfast meal, followed 4 hours later by a 5 g dose of the extract and a standard lunch. Visual analog scales were administered before lunch and at intervals until an ad libitum pizza dinner served 4 hours later. Two hours after lunch a second blood draw was conducted. Mixed models were used to analyze response changes. Results: Compared to placebo, consuming the spinach extract reduced hunger (p < 0.01) and longing for food over 2 hours (p < 0.01) and increased postprandial plasma glucose concentrations (p < 0.01). There were no differences in plasma lipids and energy intake at dinner, but males showed a trend toward decreased energy intake (p = 0.08). Conclusions: At this dose, the spinach extract containing thylakoids increases satiety over a 2-hour period compared to a placebo. Thylakoid consumption may influence gender-specific food cravings. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8195202
- author
- Rebello, Candida J. ; Chu, Jessica ; Beyl, Robbie ; Edwall, Dan ; Erlanson-Albertsson, Charlotte LU and Greenway, Frank L.
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- thylakoids, spinach, satiety, food cravings, fat digestion
- in
- Journal of the American College of Nutrition
- volume
- 34
- issue
- 6
- pages
- 470 - 477
- publisher
- American College of Nutrition
- external identifiers
-
- wos:000362555400002
- scopus:84944154638
- pmid:26029978
- ISSN
- 0731-5724
- DOI
- 10.1080/07315724.2014.1003999
- language
- English
- LU publication?
- yes
- id
- 938c3d6c-47c8-4c45-bb8c-db56359d39fb (old id 8195202)
- date added to LUP
- 2016-04-01 13:10:17
- date last changed
- 2022-02-04 02:47:01
@article{938c3d6c-47c8-4c45-bb8c-db56359d39fb,
abstract = {{Objective: By retarding fat digestion, thylakoids, the internal photosynthetic membrane system of green plants, promote the release of satiety hormones. This study examined the effect of consuming a single dose of concentrated extract of thylakoids from spinach on satiety, food intake, lipids, and glucose compared to a placebo. Design: Sixty overweight and obese individuals enrolled in a double-blind randomized crossover study consumed the spinach extract or placebo in random order at least a week apart. Blood was drawn for assessments of lipids and glucose before a standard breakfast meal, followed 4 hours later by a 5 g dose of the extract and a standard lunch. Visual analog scales were administered before lunch and at intervals until an ad libitum pizza dinner served 4 hours later. Two hours after lunch a second blood draw was conducted. Mixed models were used to analyze response changes. Results: Compared to placebo, consuming the spinach extract reduced hunger (p < 0.01) and longing for food over 2 hours (p < 0.01) and increased postprandial plasma glucose concentrations (p < 0.01). There were no differences in plasma lipids and energy intake at dinner, but males showed a trend toward decreased energy intake (p = 0.08). Conclusions: At this dose, the spinach extract containing thylakoids increases satiety over a 2-hour period compared to a placebo. Thylakoid consumption may influence gender-specific food cravings.}},
author = {{Rebello, Candida J. and Chu, Jessica and Beyl, Robbie and Edwall, Dan and Erlanson-Albertsson, Charlotte and Greenway, Frank L.}},
issn = {{0731-5724}},
keywords = {{thylakoids; spinach; satiety; food cravings; fat digestion}},
language = {{eng}},
number = {{6}},
pages = {{470--477}},
publisher = {{American College of Nutrition}},
series = {{Journal of the American College of Nutrition}},
title = {{Acute Effects of a Spinach Extract Rich in Thylakoids on Satiety: A Randomized Controlled Crossover Trial}},
url = {{https://lup.lub.lu.se/search/files/3200772/8863141.pdf}},
doi = {{10.1080/07315724.2014.1003999}},
volume = {{34}},
year = {{2015}},
}