The ability to maintain rhythm is predictive of ADHD diagnosis and profile
Gustafsson, Peik LU ; Kjell, Katarina LU ; Cundari, Maurizio LU ; Larsson, Martin ; Edbladh, Jenny ; Madison, Guy ; Kazakova, Olga and Rasmussen, Anders LU
(2023)
In BMC Psychiatry
23(1).
p.1-13
- Abstract
Attention deficit hyperactivity disorder (ADHD) is the most prevalent neuropsychiatric disorder in the world. Currently, the diagnosis is based mainly on interviews, resulting in uncertainties in the clinical assessment. While some neuropsychological tests are used, their specificity and selectivity are low, and more reliable biomarkers are desirable. Previous research indicates that ADHD is associated with morphological changes in the cerebellum, which is essential for motor ability and timing. Here, we compared 29 children diagnosed with ADHD to 96 age-matched controls on prism adaptation, eyeblink conditioning, and timed motor performance in a finger tapping task. Prism adaptation and timing precision in the finger tapping task, but... (More)
Attention deficit hyperactivity disorder (ADHD) is the most prevalent neuropsychiatric disorder in the world. Currently, the diagnosis is based mainly on interviews, resulting in uncertainties in the clinical assessment. While some neuropsychological tests are used, their specificity and selectivity are low, and more reliable biomarkers are desirable. Previous research indicates that ADHD is associated with morphological changes in the cerebellum, which is essential for motor ability and timing. Here, we compared 29 children diagnosed with ADHD to 96 age-matched controls on prism adaptation, eyeblink conditioning, and timed motor performance in a finger tapping task. Prism adaptation and timing precision in the finger tapping task, but not performance on eyeblink conditioning, differed between the ADHD and control groups, as well as between children with and without Deficits in Attention, Motor control, and Perception (DAMP) - a more severe form of ADHD. The results suggest finger tapping can be used as a cheap, objective, and unbiased biomarker to complement current diagnostic procedures.
(Less)
- author
- Gustafsson, Peik
LU
; Kjell, Katarina
LU
; Cundari, Maurizio
LU
; Larsson, Martin
; Edbladh, Jenny
; Madison, Guy
; Kazakova, Olga
and Rasmussen, Anders
LU
- organization
- publishing date
- 2023-12-08
- type
- Contribution to journal
- publication status
- published
- subject
- in
- BMC Psychiatry
- volume
- 23
- issue
- 1
- article number
- 920
- pages
- 1 - 13
- publisher
- BioMed Central (BMC)
- external identifiers
-
- scopus:85178937660
- pmid:38066477
- ISSN
- 1471-244X
- DOI
- 10.1186/s12888-023-05401-8
- language
- English
- LU publication?
- yes
- additional info
- © 2023. The Author(s).
- id
- 81b3da56-615c-41ef-9aa0-42309f97692d
- date added to LUP
- 2023-12-14 16:02:10
- date last changed
- 2024-04-13 19:59:19
@article{81b3da56-615c-41ef-9aa0-42309f97692d,
abstract = {{<p>Attention deficit hyperactivity disorder (ADHD) is the most prevalent neuropsychiatric disorder in the world. Currently, the diagnosis is based mainly on interviews, resulting in uncertainties in the clinical assessment. While some neuropsychological tests are used, their specificity and selectivity are low, and more reliable biomarkers are desirable. Previous research indicates that ADHD is associated with morphological changes in the cerebellum, which is essential for motor ability and timing. Here, we compared 29 children diagnosed with ADHD to 96 age-matched controls on prism adaptation, eyeblink conditioning, and timed motor performance in a finger tapping task. Prism adaptation and timing precision in the finger tapping task, but not performance on eyeblink conditioning, differed between the ADHD and control groups, as well as between children with and without Deficits in Attention, Motor control, and Perception (DAMP) - a more severe form of ADHD. The results suggest finger tapping can be used as a cheap, objective, and unbiased biomarker to complement current diagnostic procedures.</p>}},
author = {{Gustafsson, Peik and Kjell, Katarina and Cundari, Maurizio and Larsson, Martin and Edbladh, Jenny and Madison, Guy and Kazakova, Olga and Rasmussen, Anders}},
issn = {{1471-244X}},
language = {{eng}},
month = {{12}},
number = {{1}},
pages = {{1--13}},
publisher = {{BioMed Central (BMC)}},
series = {{BMC Psychiatry}},
title = {{The ability to maintain rhythm is predictive of ADHD diagnosis and profile}},
url = {{http://dx.doi.org/10.1186/s12888-023-05401-8}},
doi = {{10.1186/s12888-023-05401-8}},
volume = {{23}},
year = {{2023}},
}