Use of an enhanced gradient system for diffusion MR imaging with motion-artifact reduction
(1995) In Acta Radiologica 36(6). p.662-670- Abstract
- PURPOSE: A spin-echo diffusion-sensitized pulse sequence using high gradients (23 mT/m) is introduced. MATERIAL AND METHODS: In order to minimize motion artefacts, velocity-compensating gradients, ECG-triggering and post-processing with phase correction and raw data averaging using navigator echoes was performed. The in vitro ratio of diffusion coefficients for water and acetone was determined and the water self-diffusion coefficient at different temperatures was evaluated. The pulse sequence was tested in 7 healthy volunteers and in 2 tumour patients with astrocytomas of grades I-II and III-IV. Both single-slice and multi-slice techniques were used. RESULTS: The incorporation of phase correction clearly improved the quality of both... (More)
- PURPOSE: A spin-echo diffusion-sensitized pulse sequence using high gradients (23 mT/m) is introduced. MATERIAL AND METHODS: In order to minimize motion artefacts, velocity-compensating gradients, ECG-triggering and post-processing with phase correction and raw data averaging using navigator echoes was performed. The in vitro ratio of diffusion coefficients for water and acetone was determined and the water self-diffusion coefficient at different temperatures was evaluated. The pulse sequence was tested in 7 healthy volunteers and in 2 tumour patients with astrocytomas of grades I-II and III-IV. Both single-slice and multi-slice techniques were used. RESULTS: The incorporation of phase correction clearly improved the quality of both diffusion-encoded images and the calculated diffusion maps. Mean values of the diffusion coefficients in vivo were for CSF 2.66 x 10(-9) m2/s and for white and grey matter 0.69 x 10(-9) m2/s and 0.87 x 10(-9) m2/s, respectively. CONCLUSION: Velocity-compensating gradients in combination with a high gradient strength were shown to be useful for in vivo diffusion MR imaging. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1108736
- author
- Brockstedt, Sara LU ; Thomsen, C ; Wirestam, Ronnie LU ; De Poorter, J ; De Wagter, C ; Salford, Leif LU ; Holtås, Stig LU and Ståhlberg, Freddy LU
- organization
- publishing date
- 1995
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Radiologica
- volume
- 36
- issue
- 6
- pages
- 662 - 670
- publisher
- SAGE Publications
- external identifiers
-
- pmid:8519581
- scopus:0029400612
- ISSN
- 1600-0455
- language
- English
- LU publication?
- yes
- id
- 844cb989-59eb-4d49-b27e-d44a08872878 (old id 1108736)
- date added to LUP
- 2016-04-01 16:46:30
- date last changed
- 2021-01-03 08:52:20
@article{844cb989-59eb-4d49-b27e-d44a08872878, abstract = {{PURPOSE: A spin-echo diffusion-sensitized pulse sequence using high gradients (23 mT/m) is introduced. MATERIAL AND METHODS: In order to minimize motion artefacts, velocity-compensating gradients, ECG-triggering and post-processing with phase correction and raw data averaging using navigator echoes was performed. The in vitro ratio of diffusion coefficients for water and acetone was determined and the water self-diffusion coefficient at different temperatures was evaluated. The pulse sequence was tested in 7 healthy volunteers and in 2 tumour patients with astrocytomas of grades I-II and III-IV. Both single-slice and multi-slice techniques were used. RESULTS: The incorporation of phase correction clearly improved the quality of both diffusion-encoded images and the calculated diffusion maps. Mean values of the diffusion coefficients in vivo were for CSF 2.66 x 10(-9) m2/s and for white and grey matter 0.69 x 10(-9) m2/s and 0.87 x 10(-9) m2/s, respectively. CONCLUSION: Velocity-compensating gradients in combination with a high gradient strength were shown to be useful for in vivo diffusion MR imaging.}}, author = {{Brockstedt, Sara and Thomsen, C and Wirestam, Ronnie and De Poorter, J and De Wagter, C and Salford, Leif and Holtås, Stig and Ståhlberg, Freddy}}, issn = {{1600-0455}}, language = {{eng}}, number = {{6}}, pages = {{662--670}}, publisher = {{SAGE Publications}}, series = {{Acta Radiologica}}, title = {{Use of an enhanced gradient system for diffusion MR imaging with motion-artifact reduction}}, volume = {{36}}, year = {{1995}}, }