Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Effect of muesli with 4 g oat beta-glucan on postprandial blood glucose, gastric emptying and satiety in healthy subjects: a randomized crossover trial.

Hlebowicz, Joanna LU ; Darwiche, Gassan ; Björgell, Ola LU and Almér, Lars-Olof LU (2008) In Journal of the American College of Nutrition 27(4). p.470-475
Abstract
OBJECTIVE: Products enriched with oat beta-glucan have been shown to reduce postprandial glucose and insulinemic responses. The aim of this study was to evaluate the effect of an extruded muesli product based on oat beta-glucan on the rate of gastric emptying, postprandial blood glucose and satiety in healthy subjects. METHODS: Gastric emptying rate (GER) was measured by standardized real-time ultrasonography. Twelve healthy subjects were assessed using a randomized crossover double blind trial. The meals were administered after 8 hours' fasting after measuring the subject's normal fasting blood glucose level. Blood glucose measurements were made before, 30 and 60 min after the end of the meal. Satiety scores were estimated 15 and 90 min... (More)
OBJECTIVE: Products enriched with oat beta-glucan have been shown to reduce postprandial glucose and insulinemic responses. The aim of this study was to evaluate the effect of an extruded muesli product based on oat beta-glucan on the rate of gastric emptying, postprandial blood glucose and satiety in healthy subjects. METHODS: Gastric emptying rate (GER) was measured by standardized real-time ultrasonography. Twelve healthy subjects were assessed using a randomized crossover double blind trial. The meals were administered after 8 hours' fasting after measuring the subject's normal fasting blood glucose level. Blood glucose measurements were made before, 30 and 60 min after the end of the meal. Satiety scores were estimated 15 and 90 min after the end of the meal. The GER was calculated as the percentage change in the antral cross-sectional area 15 and 90 minutes after ingestion of vanilla yoghurt with muesli containing 4 g oat beta-glucan (GER1) or vanilla yoghurt with muesli containing cornflakes (GER2). RESULTS: The median values were 60% for GER1 and 44% for GER2. The effect of 4 g oat beta-glucan on the rate of gastric emptying was not statistically significant compared with corn flakes. Muesli with 4 g oat beta-glucan lowered the postprandial glucose response significantly compared to the cornflakes meal (p = 0.045). The effect of oat beta-glucan on satiety was not statistically significantly. CONCLUSIONS: The results of this study suggest that intake of muesli with 4 g oat beta-glucan does not affect the gastric emptying rate or satiety but lowers the postprandial blood glucose response, indicating that the GER does not regulate the blood glucose level. (Less)
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of the American College of Nutrition
volume
27
issue
4
pages
470 - 475
publisher
American College of Nutrition
external identifiers
  • wos:000260934500005
  • pmid:18978166
  • scopus:58749086761
ISSN
0731-5724
language
English
LU publication?
yes
id
8f0435a2-acd6-4c87-8d03-80a9ae48baf5 (old id 1271866)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18978166?dopt=Abstract
date added to LUP
2016-04-01 13:33:29
date last changed
2022-04-14 01:47:51
@article{8f0435a2-acd6-4c87-8d03-80a9ae48baf5,
  abstract     = {{OBJECTIVE: Products enriched with oat beta-glucan have been shown to reduce postprandial glucose and insulinemic responses. The aim of this study was to evaluate the effect of an extruded muesli product based on oat beta-glucan on the rate of gastric emptying, postprandial blood glucose and satiety in healthy subjects. METHODS: Gastric emptying rate (GER) was measured by standardized real-time ultrasonography. Twelve healthy subjects were assessed using a randomized crossover double blind trial. The meals were administered after 8 hours' fasting after measuring the subject's normal fasting blood glucose level. Blood glucose measurements were made before, 30 and 60 min after the end of the meal. Satiety scores were estimated 15 and 90 min after the end of the meal. The GER was calculated as the percentage change in the antral cross-sectional area 15 and 90 minutes after ingestion of vanilla yoghurt with muesli containing 4 g oat beta-glucan (GER1) or vanilla yoghurt with muesli containing cornflakes (GER2). RESULTS: The median values were 60% for GER1 and 44% for GER2. The effect of 4 g oat beta-glucan on the rate of gastric emptying was not statistically significant compared with corn flakes. Muesli with 4 g oat beta-glucan lowered the postprandial glucose response significantly compared to the cornflakes meal (p = 0.045). The effect of oat beta-glucan on satiety was not statistically significantly. CONCLUSIONS: The results of this study suggest that intake of muesli with 4 g oat beta-glucan does not affect the gastric emptying rate or satiety but lowers the postprandial blood glucose response, indicating that the GER does not regulate the blood glucose level.}},
  author       = {{Hlebowicz, Joanna and Darwiche, Gassan and Björgell, Ola and Almér, Lars-Olof}},
  issn         = {{0731-5724}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{470--475}},
  publisher    = {{American College of Nutrition}},
  series       = {{Journal of the American College of Nutrition}},
  title        = {{Effect of muesli with 4 g oat beta-glucan on postprandial blood glucose, gastric emptying and satiety in healthy subjects: a randomized crossover trial.}},
  url          = {{http://www.ncbi.nlm.nih.gov/pubmed/18978166?dopt=Abstract}},
  volume       = {{27}},
  year         = {{2008}},
}