Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.
Agardh, Elisabet LU ; Lundstig, Annika LU ; Perfilyev, Alexander LU
; Volkov, Petr
LU
; Freiburghaus, Tove
LU
; Lindholm, Eero
LU
; Rönn, Tina
LU
; Agardh, Carl-David
LU
and Ling, Charlotte
LU
(2015)
In BMC Medicine
13(182).
- Abstract
- Epigenetic variation has been linked to several human diseases. Proliferative diabetic retinopathy (PDR) is a major cause of vision loss in subjects with diabetes. However, studies examining the association between PDR and the genome-wide DNA methylation pattern are lacking. Our aim was to identify epigenetic modifications that associate with and predict PDR in subjects with type 1 diabetes (T1D).
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7844528
- author
- Agardh, Elisabet
LU
; Lundstig, Annika
LU
; Perfilyev, Alexander
LU
; Volkov, Petr
LU
; Freiburghaus, Tove
LU
; Lindholm, Eero
LU
; Rönn, Tina
LU
; Agardh, Carl-David
LU
and Ling, Charlotte
LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- BMC Medicine
- volume
- 13
- issue
- 182
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:26248552
- wos:000359149600001
- scopus:84938566124
- pmid:26248552
- ISSN
- 1741-7015
- DOI
- 10.1186/s12916-015-0421-5
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Diabetes and Celiac Unit (013241540), Diabetes and Endocrinology (013241530), Unit on Vascular Diabetic Complications (013241510), Faculty of Medicine (000022000), Epigenetics and Diabetes (013241505), Ophthalmology (013242810)
- id
- 98e46881-2748-40a0-a207-6ac49b962f46 (old id 7844528)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26248552?dopt=Abstract
- date added to LUP
- 2016-04-01 12:59:04
- date last changed
- 2025-10-14 11:11:15
@article{98e46881-2748-40a0-a207-6ac49b962f46,
abstract = {{Epigenetic variation has been linked to several human diseases. Proliferative diabetic retinopathy (PDR) is a major cause of vision loss in subjects with diabetes. However, studies examining the association between PDR and the genome-wide DNA methylation pattern are lacking. Our aim was to identify epigenetic modifications that associate with and predict PDR in subjects with type 1 diabetes (T1D).}},
author = {{Agardh, Elisabet and Lundstig, Annika and Perfilyev, Alexander and Volkov, Petr and Freiburghaus, Tove and Lindholm, Eero and Rönn, Tina and Agardh, Carl-David and Ling, Charlotte}},
issn = {{1741-7015}},
language = {{eng}},
number = {{182}},
publisher = {{BioMed Central (BMC)}},
series = {{BMC Medicine}},
title = {{Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.}},
url = {{https://lup.lub.lu.se/search/files/3087438/8603190}},
doi = {{10.1186/s12916-015-0421-5}},
volume = {{13}},
year = {{2015}},
}