Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Serotonin and adipocyte function

Fex, Malin LU and Stenkula, Karin G. LU (2019) p.197-202
Abstract

The ability to store and mobilize energy is fundamental for physiologic function. Most excess energy is stored in adipose tissue as triglycerides, which is released as free fatty acids when needed through cellular processes tightly regulated by insulin. Intact adipose cell function is essential to regulate whole-body glucose and lipid metabolism. Several studies have focused on the metabolic impact of 5-hydroxytryptamine (5-HT) on lipid metabolism and glucose homeostasis, and it has been demonstrated that circulating 5-HT, through different routes of action, exerts adipocyte-specific effects that influence both lipid- and glucose metabolism as well as cytokine secretion.

Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
5-HT, Adipocytes, Adipose tissue, Free fatty acids, Insulin signaling
host publication
Serotonin : The Mediator that Spans Evolution - The Mediator that Spans Evolution
editor
Pilowsky, Paul M
pages
6 pages
publisher
Academic Press
external identifiers
  • scopus:85080815287
ISBN
9780128000502
DOI
10.1016/B978-0-12-800050-2.00011-5
language
English
LU publication?
yes
id
a1919132-3749-4be0-a01b-9da8a7bf1341
date added to LUP
2020-03-26 16:02:10
date last changed
2025-04-04 15:37:47
@inbook{a1919132-3749-4be0-a01b-9da8a7bf1341,
  abstract     = {{<p>The ability to store and mobilize energy is fundamental for physiologic function. Most excess energy is stored in adipose tissue as triglycerides, which is released as free fatty acids when needed through cellular processes tightly regulated by insulin. Intact adipose cell function is essential to regulate whole-body glucose and lipid metabolism. Several studies have focused on the metabolic impact of 5-hydroxytryptamine (5-HT) on lipid metabolism and glucose homeostasis, and it has been demonstrated that circulating 5-HT, through different routes of action, exerts adipocyte-specific effects that influence both lipid- and glucose metabolism as well as cytokine secretion.</p>}},
  author       = {{Fex, Malin and Stenkula, Karin G.}},
  booktitle    = {{Serotonin : The Mediator that Spans Evolution}},
  editor       = {{Pilowsky, Paul M}},
  isbn         = {{9780128000502}},
  keywords     = {{5-HT; Adipocytes; Adipose tissue; Free fatty acids; Insulin signaling}},
  language     = {{eng}},
  pages        = {{197--202}},
  publisher    = {{Academic Press}},
  title        = {{Serotonin and adipocyte function}},
  url          = {{http://dx.doi.org/10.1016/B978-0-12-800050-2.00011-5}},
  doi          = {{10.1016/B978-0-12-800050-2.00011-5}},
  year         = {{2019}},
}