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Gastrointestinal digestion and colonic fermentation : Beyond classic food science

Blancas-Benítez, Francisco J. ; Zamora-Gasga, Víctor M. ; Tovar, Juscelino LU orcid and Sáyago-Ayerdi, Sonia G. (2024) p.157-174
Abstract
Several digestive system models have been developed, varying in sophistication. These models measure under dynamic, semi-dynamic, or batch conditions, with notable distinctions between them. This chapter covers models for gastrointestinal digestion, including static and dynamic models, and important aspects of digestion and fermentation, such as bioaccessibility, bioavailability, and bioconversion of bioactive compounds (BCs) into different metabolites. The use of natural ingredients rich in BCs has become increasingly popular, especially with the growing inclusion of plant-based foods. However, not all BCs are easily absorbed in the upper gastrointestinal (GI) tract. The number of BCs that are not absorbed and instead reach the colon can... (More)
Several digestive system models have been developed, varying in sophistication. These models measure under dynamic, semi-dynamic, or batch conditions, with notable distinctions between them. This chapter covers models for gastrointestinal digestion, including static and dynamic models, and important aspects of digestion and fermentation, such as bioaccessibility, bioavailability, and bioconversion of bioactive compounds (BCs) into different metabolites. The use of natural ingredients rich in BCs has become increasingly popular, especially with the growing inclusion of plant-based foods. However, not all BCs are easily absorbed in the upper gastrointestinal (GI) tract. The number of BCs that are not absorbed and instead reach the colon can vary significantly. Therefore, evaluating the bioaccessibility and conducting clinical trials to study bioavailability, as well as the bioconversion of the non-digestible fraction by the gut microbiota, are of particular interest. This chapter also discusses the importance of analyzing the BC content in food products and the need for clinical trials to study its bioavailability and bioconversion by the gut microbiota. The discussion also includes the relevance of considering this type of analysis for the development of new food products with higher BC contents. (Less)
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author
; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Health-Promoting Food Ingredients During Processing
editor
Mora-Escobedo, Rosalva ; Dávila-Ortiz, Gloria ; Gutiérrez López, Gustavo F. and Berrios, José J.
edition
1st Edition
pages
18 pages
publisher
CRC Press
external identifiers
  • scopus:85206925549
ISBN
9781032365367
9781040131428
9781003332558
DOI
10.1201/9781003332558-11
language
English
LU publication?
yes
id
b2740f2d-e9ce-4317-8add-950dbca9e527
date added to LUP
2024-11-04 11:03:30
date last changed
2025-07-01 08:19:47
@inbook{b2740f2d-e9ce-4317-8add-950dbca9e527,
  abstract     = {{Several digestive system models have been developed, varying in sophistication. These models measure under dynamic, semi-dynamic, or batch conditions, with notable distinctions between them. This chapter covers models for gastrointestinal digestion, including static and dynamic models, and important aspects of digestion and fermentation, such as bioaccessibility, bioavailability, and bioconversion of bioactive compounds (BCs) into different metabolites. The use of natural ingredients rich in BCs has become increasingly popular, especially with the growing inclusion of plant-based foods. However, not all BCs are easily absorbed in the upper gastrointestinal (GI) tract. The number of BCs that are not absorbed and instead reach the colon can vary significantly. Therefore, evaluating the bioaccessibility and conducting clinical trials to study bioavailability, as well as the bioconversion of the non-digestible fraction by the gut microbiota, are of particular interest. This chapter also discusses the importance of analyzing the BC content in food products and the need for clinical trials to study its bioavailability and bioconversion by the gut microbiota. The discussion also includes the relevance of considering this type of analysis for the development of new food products with higher BC contents.}},
  author       = {{Blancas-Benítez, Francisco J. and Zamora-Gasga, Víctor M. and Tovar, Juscelino and Sáyago-Ayerdi, Sonia G.}},
  booktitle    = {{Health-Promoting Food Ingredients During Processing}},
  editor       = {{Mora-Escobedo, Rosalva and Dávila-Ortiz, Gloria and Gutiérrez López, Gustavo F. and Berrios, José J.}},
  isbn         = {{9781032365367}},
  language     = {{eng}},
  month        = {{10}},
  pages        = {{157--174}},
  publisher    = {{CRC Press}},
  title        = {{Gastrointestinal digestion and colonic fermentation : Beyond classic food science}},
  url          = {{http://dx.doi.org/10.1201/9781003332558-11}},
  doi          = {{10.1201/9781003332558-11}},
  year         = {{2024}},
}