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Advancing breast tissue imaging with an ultrasound optical tomography (UOT) approach

Ruchkina, Maria LU ; Zabiliute-Karaliune, Akvile LU ; Bukarte, Egle LU ; Kinos, Adam LU ; Hill, David LU ; Bengtsson, Alexander LU ; Shortiss, Kevin LU ; Reistad, Nina LU orcid ; Rippe, Lars LU and Swartling, Johannes , et al. (2024) SPIE Photonics Europe, 2024, Strasbourg, France 13010. p.1301006-1301006
Abstract
Each year, about 30% of all newly diagnosed cancer cases in women worldwide are breast cancers [1]. One of the most common techniques for breast cancer diagnosis is mammography. However, this technique provides limited functional information regarding breast tissue morphology. In cases of suspected malignancy invasive techniques such as biopsy are implemented.
In this work an optical deep tissue imaging technique called ultrasound optical tomography (UOT) which combines laser light and ultrasound is implemented for a non-invasive lesion (tumour) characterization in breast tissue.
The experiments were performed using 794 nm laser wavelength, 6 MHz ultrasound frequency and a narrowband spectral filter material, Tm3+:LiNbO3. The... (More)
Each year, about 30% of all newly diagnosed cancer cases in women worldwide are breast cancers [1]. One of the most common techniques for breast cancer diagnosis is mammography. However, this technique provides limited functional information regarding breast tissue morphology. In cases of suspected malignancy invasive techniques such as biopsy are implemented.
In this work an optical deep tissue imaging technique called ultrasound optical tomography (UOT) which combines laser light and ultrasound is implemented for a non-invasive lesion (tumour) characterization in breast tissue.
The experiments were performed using 794 nm laser wavelength, 6 MHz ultrasound frequency and a narrowband spectral filter material, Tm3+:LiNbO3. The measurements were carried out in 5 cm thick agar phantoms using a range of tumor mimicking inclusions of 3 different sizes.
This work is the first deep tissue imaging demonstration using UOT at tissue relevant wavelengths. Current results indicate that the UOT technique can become an important and valuable tool for lesion characterization in breast tissue. (Less)
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organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
breast cancer, bio-medical imaging, diagnosis, ultrasound optical tomography, deep tissue imaging, acousto-optic effect, spectral-hole-burning filters, rare-earth-ion-doped crystals
host publication
Tissue Optics and Photonics III : PROCEEDINGS VOLUME 13010 SPIE PHOTONICS EUROPE | 7-12 APRIL 2024 - PROCEEDINGS VOLUME 13010 SPIE PHOTONICS EUROPE | 7-12 APRIL 2024
editor
Tuchin, Valery V. ; Blondel, Walter C.P.M. and Zalevsky, Zeev
volume
13010
pages
6 pages
publisher
SPIE
conference name
SPIE Photonics Europe, 2024, Strasbourg, France
conference location
Strasbourg, France
conference dates
2024-06-18
external identifiers
  • scopus:85203186506
DOI
10.1117/12.3023883
language
English
LU publication?
yes
id
b4cad3bf-83e4-4957-a54c-f94b92d87ac5
date added to LUP
2024-09-13 14:38:08
date last changed
2024-09-16 09:45:38
@inproceedings{b4cad3bf-83e4-4957-a54c-f94b92d87ac5,
  abstract     = {{Each year, about 30% of all newly diagnosed cancer cases in women worldwide are breast cancers [1]. One of the most common techniques for breast cancer diagnosis is mammography. However, this technique provides limited functional information regarding breast tissue morphology. In cases of suspected malignancy invasive techniques such as biopsy are implemented.<br/>In this work an optical deep tissue imaging technique called ultrasound optical tomography (UOT) which combines laser light and ultrasound is implemented for a non-invasive lesion (tumour) characterization in breast tissue.<br/>The experiments were performed using 794 nm laser wavelength, 6 MHz ultrasound frequency and a narrowband spectral filter material, Tm3+:LiNbO3. The measurements were carried out in 5 cm thick agar phantoms using a range of tumor mimicking inclusions of 3 different sizes.<br/>This work is the first deep tissue imaging demonstration using UOT at tissue relevant wavelengths. Current results indicate that the UOT technique can become an important and valuable tool for lesion characterization in breast tissue.}},
  author       = {{Ruchkina, Maria and Zabiliute-Karaliune, Akvile and Bukarte, Egle and Kinos, Adam and Hill, David and Bengtsson, Alexander and Shortiss, Kevin and Reistad, Nina and Rippe, Lars and Swartling, Johannes and Zackrisson, Sophia and Bakic, Predrag and Kovacs, Laszlo and Kis, Zsolt and Szaller, Zsuzsanna and Lengyel, Krisztian and Thiel, Charles and Kröll, Stefan}},
  booktitle    = {{Tissue Optics and Photonics III : PROCEEDINGS VOLUME 13010 SPIE PHOTONICS EUROPE | 7-12 APRIL 2024}},
  editor       = {{Tuchin, Valery V. and Blondel, Walter C.P.M. and Zalevsky, Zeev}},
  keywords     = {{breast cancer; bio-medical imaging; diagnosis; ultrasound optical tomography; deep tissue imaging; acousto-optic effect; spectral-hole-burning filters; rare-earth-ion-doped crystals}},
  language     = {{eng}},
  pages        = {{1301006--1301006}},
  publisher    = {{SPIE}},
  title        = {{Advancing breast tissue imaging with an ultrasound optical tomography (UOT) approach}},
  url          = {{http://dx.doi.org/10.1117/12.3023883}},
  doi          = {{10.1117/12.3023883}},
  volume       = {{13010}},
  year         = {{2024}},
}