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Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function

Riesbeck, Kristian LU orcid and Forsgren, Arne LU (1994) In Antimicrobial Agents and Chemotherapy 38(4). p.879-882
Abstract

Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.

Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Antimicrobial Agents and Chemotherapy
volume
38
issue
4
pages
879 - 882
publisher
American Society for Microbiology
external identifiers
  • scopus:0028265747
  • pmid:8031064
ISSN
0066-4804
DOI
10.1128/AAC.38.4.879
language
English
LU publication?
yes
id
c7bce6e1-bd22-417d-8fb7-aae74e3e224f
date added to LUP
2019-03-08 15:27:19
date last changed
2025-10-14 11:10:45
@misc{c7bce6e1-bd22-417d-8fb7-aae74e3e224f,
  abstract     = {{<p>Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.</p>}},
  author       = {{Riesbeck, Kristian and Forsgren, Arne}},
  issn         = {{0066-4804}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{4}},
  pages        = {{879--882}},
  publisher    = {{American Society for Microbiology}},
  series       = {{Antimicrobial Agents and Chemotherapy}},
  title        = {{Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function}},
  url          = {{http://dx.doi.org/10.1128/AAC.38.4.879}},
  doi          = {{10.1128/AAC.38.4.879}},
  volume       = {{38}},
  year         = {{1994}},
}