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Silicon sieve electrodes for neural implants - in vitro characterization & in vivo recordings

Wallman, L. LU ; Levinsson, A. LU ; Schouenborg, J. LU ; Holmberg, H. ; Montelius, L. LU ; Danielsen, N. LU and Laurell, T. LU (1998) 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society 20. p.2225-2228
Abstract

An in vitro model was developed to characterize the electrical properties of silicon microfabricated recording electrodes, using a Cu-wire mimicing a neural signal source. Phosphorous doped electrodes were used to achieve an all silicon device. The model was used to study signal amplitude as a function of distance between the electrode surface and the signal source. Signal crosstalk to neighbouring electrodes on the chips were recorded. The crosstalk was found to be 6 dB using an external reference electrode. Improvements were accomplished with an on chip reference electrode giving an amplitude crosstalk suppression of 20 dB. It was found that the amplitude decreased by a factor of 2 at a distance of 50 μm between the electrode surface... (More)

An in vitro model was developed to characterize the electrical properties of silicon microfabricated recording electrodes, using a Cu-wire mimicing a neural signal source. Phosphorous doped electrodes were used to achieve an all silicon device. The model was used to study signal amplitude as a function of distance between the electrode surface and the signal source. Signal crosstalk to neighbouring electrodes on the chips were recorded. The crosstalk was found to be 6 dB using an external reference electrode. Improvements were accomplished with an on chip reference electrode giving an amplitude crosstalk suppression of 20 dB. It was found that the amplitude decreased by a factor of 2 at a distance of 50 μm between the electrode surface and the signal source. Sieve electrodes were also implanted in the rat sciatic nerve and following a 10 week nerve regeneration period the dorsal and ventral (L5) roots in the spinal cord were stimulated. Compound action potentials were recorded via the chip. Lower leg muscle contraction activity was also induced by stimulating the regenerated sciatic nerve via the sieve electrode.

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author
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organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Procceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society : Biomedical Engineering Towards the Year 2000 and Beyond - Biomedical Engineering Towards the Year 2000 and Beyond
volume
20
pages
2225 - 2228
publisher
IEEE - Institute of Electrical and Electronics Engineers Inc.
conference name
20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
conference location
Hongkong, China
conference dates
1998-11-01
external identifiers
  • scopus:0032284597
ISBN
0-7803-5164-9
DOI
10.1109/IEMBS.1998.747054
language
English
LU publication?
yes
id
d1d6a011-a7a4-49b2-a7cd-cb626499834e
date added to LUP
2019-06-25 16:05:15
date last changed
2022-03-26 00:55:42
@inproceedings{d1d6a011-a7a4-49b2-a7cd-cb626499834e,
  abstract     = {{<p>An in vitro model was developed to characterize the electrical properties of silicon microfabricated recording electrodes, using a Cu-wire mimicing a neural signal source. Phosphorous doped electrodes were used to achieve an all silicon device. The model was used to study signal amplitude as a function of distance between the electrode surface and the signal source. Signal crosstalk to neighbouring electrodes on the chips were recorded. The crosstalk was found to be 6 dB using an external reference electrode. Improvements were accomplished with an on chip reference electrode giving an amplitude crosstalk suppression of 20 dB. It was found that the amplitude decreased by a factor of 2 at a distance of 50 μm between the electrode surface and the signal source. Sieve electrodes were also implanted in the rat sciatic nerve and following a 10 week nerve regeneration period the dorsal and ventral (L5) roots in the spinal cord were stimulated. Compound action potentials were recorded via the chip. Lower leg muscle contraction activity was also induced by stimulating the regenerated sciatic nerve via the sieve electrode.</p>}},
  author       = {{Wallman, L. and Levinsson, A. and Schouenborg, J. and Holmberg, H. and Montelius, L. and Danielsen, N. and Laurell, T.}},
  booktitle    = {{Procceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society : Biomedical Engineering Towards the Year 2000 and Beyond}},
  isbn         = {{0-7803-5164-9}},
  language     = {{eng}},
  month        = {{12}},
  pages        = {{2225--2228}},
  publisher    = {{IEEE - Institute of Electrical and Electronics Engineers Inc.}},
  title        = {{Silicon sieve electrodes for neural implants - in vitro characterization & in vivo recordings}},
  url          = {{http://dx.doi.org/10.1109/IEMBS.1998.747054}},
  doi          = {{10.1109/IEMBS.1998.747054}},
  volume       = {{20}},
  year         = {{1998}},
}