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Semi-automated QRS score as a predictor of survival in CRT treated patients with strict left bundle branch block

Reitan, C. LU ; Chaudhry, U. LU ; Atwater, B.; Jacobsson, J. LU ; Couderc, J. P.; Xia, X.; Carlson, J. LU ; Platonov, P. G. LU and Borgquist, R. LU (2017) In Journal of Electrocardiology
Abstract

Background: Cardiac Resynchronization Therapy (CRT) is widely used for treating selected heart failure patients, but patients with myocardial scar respond worse to treatment. The Selvester QRS scoring system estimates myocardial scar burden using 12-lead ECG. This study's objective was to investigate the scores correlation to mortality in a CRT population. Methods and results: Data on consecutive CRT patients was collected. 401 patients with LBBB and available ECG data were included in the study. QuAReSS software was used to perform Selvester scoring. Mean Selvester score was 6.4, corresponding to 19% scar burden. The endpoint was death or heart transplant; outcome was analyzed using Cox proportional hazards models. A Selvester score... (More)

Background: Cardiac Resynchronization Therapy (CRT) is widely used for treating selected heart failure patients, but patients with myocardial scar respond worse to treatment. The Selvester QRS scoring system estimates myocardial scar burden using 12-lead ECG. This study's objective was to investigate the scores correlation to mortality in a CRT population. Methods and results: Data on consecutive CRT patients was collected. 401 patients with LBBB and available ECG data were included in the study. QuAReSS software was used to perform Selvester scoring. Mean Selvester score was 6.4, corresponding to 19% scar burden. The endpoint was death or heart transplant; outcome was analyzed using Cox proportional hazards models. A Selvester score >. 8 was significantly associated with higher risk of the combined endpoint (HR 1.59, p = .014, CI 1.09-2.3). Conclusion: Higher Selvester scores correlate to mortality in CRT patients with strict LBBB and might be of value in prognosticating survival.

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author
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
Cardiac Resynchronization Therapy, Electrocardiogram, Left bundle branch block, Long-term outcome, Selvester QRS score
in
Journal of Electrocardiology
publisher
Elsevier
external identifiers
  • scopus:85036645163
ISSN
0022-0736
DOI
10.1016/j.jelectrocard.2017.11.001
language
English
LU publication?
yes
id
f30a6a67-c7c0-4408-9a49-35e2a1f5c002
date added to LUP
2018-01-10 13:38:18
date last changed
2018-01-11 03:00:02
@article{f30a6a67-c7c0-4408-9a49-35e2a1f5c002,
  abstract     = {<p>Background: Cardiac Resynchronization Therapy (CRT) is widely used for treating selected heart failure patients, but patients with myocardial scar respond worse to treatment. The Selvester QRS scoring system estimates myocardial scar burden using 12-lead ECG. This study's objective was to investigate the scores correlation to mortality in a CRT population. Methods and results: Data on consecutive CRT patients was collected. 401 patients with LBBB and available ECG data were included in the study. QuAReSS software was used to perform Selvester scoring. Mean Selvester score was 6.4, corresponding to 19% scar burden. The endpoint was death or heart transplant; outcome was analyzed using Cox proportional hazards models. A Selvester score &gt;. 8 was significantly associated with higher risk of the combined endpoint (HR 1.59, p = .014, CI 1.09-2.3). Conclusion: Higher Selvester scores correlate to mortality in CRT patients with strict LBBB and might be of value in prognosticating survival.</p>},
  author       = {Reitan, C. and Chaudhry, U. and Atwater, B. and Jacobsson, J. and Couderc, J. P. and Xia, X. and Carlson, J. and Platonov, P. G. and Borgquist, R.},
  issn         = {0022-0736},
  keyword      = {Cardiac Resynchronization Therapy,Electrocardiogram,Left bundle branch block,Long-term outcome,Selvester QRS score},
  language     = {eng},
  publisher    = {Elsevier},
  series       = {Journal of Electrocardiology},
  title        = {Semi-automated QRS score as a predictor of survival in CRT treated patients with strict left bundle branch block},
  url          = {http://dx.doi.org/10.1016/j.jelectrocard.2017.11.001},
  year         = {2017},
}