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Recent advances in the analysis of vitamin D and its metabolites in food matrices

Socas-Rodríguez, Bárbara LU ; Sandahl, Margareta LU ; Holm, Cecilia LU and Turner, Charlotta LU orcid (2020) In separations 7(2).
Abstract

Vitamin D and its analogues are fat-soluble vitamins that carry out important functions in human and animal organisms. Many studies have pointed out the relationship between the deficiency of these substances and the development of both skeletal-and extra-skeletal diseases. Although vitamin D is fundamentally derived from the bio-transformation of its precursor, 7-dehydrocholesterol, through the action of UV-B radiation in the skin, dietary intake also plays an important role in the regulation of its status in an organism. For this reason, the application of reliable methodologies that enable monitoring the content of vitamin D and its analogues in food and supplements constitutes an aspect of special relevance to establish adequate... (More)

Vitamin D and its analogues are fat-soluble vitamins that carry out important functions in human and animal organisms. Many studies have pointed out the relationship between the deficiency of these substances and the development of both skeletal-and extra-skeletal diseases. Although vitamin D is fundamentally derived from the bio-transformation of its precursor, 7-dehydrocholesterol, through the action of UV-B radiation in the skin, dietary intake also plays an important role in the regulation of its status in an organism. For this reason, the application of reliable methodologies that enable monitoring the content of vitamin D and its analogues in food and supplements constitutes an aspect of special relevance to establish adequate habits, which avoid the deficiency of these substances in organisms and, consequently, the appearance of related diseases. The use of chromatographic techniques in combination with conventional and novel sample pre-treatments has become a suitable strategy to achieve this aim. This review compiles the most relevant methodologies reported in the last ten years for vitamin D analogues analysis in food matrices. Particular attention has been paid to provide a general overview of the most suitable approaches in terms of reliability, sensitivity and simplicity, used in the field of food analysis.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Chromatographic techniques, Conventional extraction, Food analysis, Miniaturized techniques, Sample preparation, Saponification, Vitamin D, Vitamin D metabolites
in
separations
volume
7
issue
2
article number
36
pages
27 pages
publisher
MDPI AG
external identifiers
  • scopus:85086913174
ISSN
2297-8739
DOI
10.3390/separations7020036
language
English
LU publication?
yes
id
f9216391-3bb1-4134-960e-21f90f6c4216
date added to LUP
2020-07-08 11:34:00
date last changed
2024-03-20 13:00:09
@article{f9216391-3bb1-4134-960e-21f90f6c4216,
  abstract     = {{<p>Vitamin D and its analogues are fat-soluble vitamins that carry out important functions in human and animal organisms. Many studies have pointed out the relationship between the deficiency of these substances and the development of both skeletal-and extra-skeletal diseases. Although vitamin D is fundamentally derived from the bio-transformation of its precursor, 7-dehydrocholesterol, through the action of UV-B radiation in the skin, dietary intake also plays an important role in the regulation of its status in an organism. For this reason, the application of reliable methodologies that enable monitoring the content of vitamin D and its analogues in food and supplements constitutes an aspect of special relevance to establish adequate habits, which avoid the deficiency of these substances in organisms and, consequently, the appearance of related diseases. The use of chromatographic techniques in combination with conventional and novel sample pre-treatments has become a suitable strategy to achieve this aim. This review compiles the most relevant methodologies reported in the last ten years for vitamin D analogues analysis in food matrices. Particular attention has been paid to provide a general overview of the most suitable approaches in terms of reliability, sensitivity and simplicity, used in the field of food analysis.</p>}},
  author       = {{Socas-Rodríguez, Bárbara and Sandahl, Margareta and Holm, Cecilia and Turner, Charlotta}},
  issn         = {{2297-8739}},
  keywords     = {{Chromatographic techniques; Conventional extraction; Food analysis; Miniaturized techniques; Sample preparation; Saponification; Vitamin D; Vitamin D metabolites}},
  language     = {{eng}},
  number       = {{2}},
  publisher    = {{MDPI AG}},
  series       = {{separations}},
  title        = {{Recent advances in the analysis of vitamin D and its metabolites in food matrices}},
  url          = {{http://dx.doi.org/10.3390/separations7020036}},
  doi          = {{10.3390/separations7020036}},
  volume       = {{7}},
  year         = {{2020}},
}