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2023
Mark Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1
Wallner, Olov ; Cázares-Körner, Armando ; Scaletti, Emma Rose ; Masuyer, Geoffrey ; Bekkhus, Tove ; Visnes, Torkild ; Mamonov, Kirill ; Ortis, Florian ; Lundbäck, Thomas and Volkova, Maria , et al. (2023) In ChemMedChem 18(1).
- Contribution to journal › Article
2020
Mark Development of a chemical probe against NUDT15
Zhang, Si Min ; Desroses, Matthieu ; Hagenkort, Anna ; Valerie, Nicholas C K ; Rehling, Daniel ; Carter, Megan ; Wallner, Olov ; Koolmeister, Tobias ; Throup, Adam and Jemth, Ann-Sofie , et al. (2020) In Nature Chemical Biology 16(10). p.1120-1128
- Contribution to journal › Article
Mark Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
Visnes, Torkild ; Benítez-Buelga, Carlos ; Cázares-Körner, Armando ; Sanjiv, Kumar ; Hanna, Bishoy M F ; Mortusewicz, Oliver ; Rajagopal, Varshni ; Albers, Julian J ; Hagey, Daniel W and Bekkhus, Tove , et al. (2020) In Nucleic Acids Research
- Contribution to journal › Article
2018
Mark Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Page, Brent D G ; Valerie, Nicholas C K ; Wright, Roni H G ; Wallner, Olov ; Isaksson, Rebecka ; Carter, Megan ; Rudd, Sean G ; Loseva, Olga ; Jemth, Ann-Sofie and Almlöf, Ingrid , et al. (2018) In Nature Communications 9(1).
- Contribution to journal › Article
Mark Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation
Visnes, Torkild ; Cázares-Körner, Armando ; Hao, Wenjing ; Wallner, Olov ; Masuyer, Geoffrey ; Loseva, Olga ; Mortusewicz, Oliver ; Wiita, Elisée ; Sarno, Antonio and Manoilov, Aleksandr , et al. (2018) In Science 362(6416). p.834-839
- Contribution to journal › Article
2017
Mark Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor
Gustafsson, Robert ; Jemth, Ann-Sofie ; Gustafsson, Nina M S ; Färnegårdh, Katarina ; Loseva, Olga ; Wiita, Elisée ; Bonagas, Nadilly ; Dahllund, Leif ; Llona-Minguez, Sabin and Häggblad, Maria , et al. (2017) In Cancer Research 77(4). p.937-948
- Contribution to journal › Article
Mark A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family
Carreras-Puigvert, Jordi ; Zitnik, Marinka ; Jemth, Ann-Sofie ; Carter, Megan ; Unterlass, Judith E ; Hallström, Björn ^LU ; Loseva, Olga ; Karem, Zhir ; Calderón-Montaño, José Manuel and Lindskog, Cecilia , et al. (2017) In Nature Communications 8(1).
- Contribution to journal › Article
2010
Mark PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA
Loseva, Olga ; Jemth, Ann-Sofie ; Bryant, Helen E ; Schüler, Herwig ^LU ; Lehtiö, Lari ; Karlberg, Tobias ^LU and Helleday, Thomas (2010) In The Journal of biological chemistry 285(11). p.60-8054
- Contribution to journal › Article
Mark Pathogen Entrapment by Transglutaminase-A Conserved Early Innate Immune Mechanism
Wang, Zhi ; Wilhelmsson, Christine ; Hyrsl, Pavel ; Loof, Torsten ^LU ; Dobes, Pavel ; Klupp, Martina ; Loseva, Olga ; Mörgelin, Matthias ^LU ; Ikle, Jennifer and Cripps, Richard M. , et al. (2010) In PLoS Pathogens 6(2).
- Contribution to journal › Article
2009
Mark Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3
Lehtiö, Lari ; Jemth, Ann-Sofie ; Collins, Ruairi ; Loseva, Olga ; Johansson, Andreas ; Markova, Natalia ^LU ; Hammarström, Martin ; Flores, Alex ; Holmberg-Schiavone, Lovisa and Weigelt, Johan , et al. (2009) In Journal of Medicinal Chemistry 52(9). p.11-3108
- Contribution to journal › Article

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