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2024
Mark Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer
Zetterberg, Fredrik R. ; Peterson, Kristoffer ; Nilsson, Ulf J. ^LU ; Andréasson Dahlgren, Kajsa ; Diehl, Carl ; Hoyler, Ian ; Håkansson, Maria ; Khabut, Areej ^LU ; Kahl-Knutson, Barbro ^LU and Leffler, Hakon ^LU , et al. (2024) In Journal of Medicinal Chemistry 67(11). p.9374-9388
- Contribution to journal › Article
Mark Elevated Galectin-3 levels in the tumor microenvironment of ovarian cancer – implication of ROS mediated suppression of NK cell antitumor response via tumor-associated neutrophils
Karlsson, Veronika ; Stål, Ebba ; Stoopendahl, Emma ; Ivarsson, Anton ; Leffler, Hakon ^LU ; Lycke, Maria ; Sundqvist, Martina ; Sundfeldt, Karin ; Christenson, Karin and Bernson, Elin (2024) In Frontiers in Immunology 15.
- Contribution to journal › Article
Mark Galectin-8N-Selective 4-Halophenylphthalazinone-Galactals Double π-Stack in a Unique Pocket
van Klaveren, Sjors ^LU ; Hassan, Mujtaba ^LU ; Håkansson, Maria ^LU ; Johnsson, Richard E. ^LU ; Larsson, Jessica ^LU ; Jakopin, Žiga ; Anderluh, Marko ^LU ; Leffler, Hakon ^LU ; Tomašič, Tihomir and Nilsson, Ulf J. ^LU (2024) In ACS Medicinal Chemistry Letters 15(8). p.1319-1324
- Contribution to journal › Article
Mark Development and Characterization of a High-Affinity Selective Galectin-3 Mouse Tool Compound in Mouse Models of Cancer
Peterson, Kristoffer ^LU ; Nilsson, Ulf J. ^LU ; Gravelle, Lise ; Holyer, Ian ; Jansson, Karl ; Kahl-Knutson, Barbro ^LU ; Leffler, Hakon ^LU ; MacKinnon, Alison C. ; Roper, James A. and Slack, Robert J. , et al. (2024) In Journal of Medicinal Chemistry 67(24). p.21905-21915
- Contribution to journal › Article
Mark Effect of GB1107, a novel galectin-3 inhibitor on pro-fibrotic signalling in the liver
MacKinnon, Alison C. ; Humphries, Duncan C. ; Herman, Kimberley ; Roper, James A. ; Holyer, Ian ; Mabbitt, Joseph ; Mills, Ross ; Nilsson, Ulf J. ^LU ; Leffler, Hakon ^LU and Pedersen, Anders , et al. (2024) In European Journal of Pharmacology 985.
- Contribution to journal › Article
Mark Sulfonamide-derivatized galactosides selectively target an unexplored binding site in the galectin-9N-terminal domain
Mahanti, Mukul ^LU ; Gummesson, Sofi ; Sundin, Anders ^LU ; Leffler, Hakon ^LU ; Zetterberg, Fredrik and Nilsson, Ulf J ^LU (2024) In Bioorganic & Medicinal Chemistry 116.
- Contribution to journal › Article
Mark Myocardin related transcription factor and galectin-3 drives lipid accumulation in human blood vessels
Arévalo-Martinez, Marycarmen ^LU ; Ede, Jacob ^LU ; van der Have, Oscar ^LU ; Ritsvall, Olivia ^LU ; Zetterberg, Fredrik R ; Nilsson, Ulf J ^LU ; Leffler, Hakon ^LU ; Holmberg, Johan ^LU and Albinsson, Sebastian ^LU (2024) In Vascular Pharmacology 156.
- Contribution to journal › Article
2023
Mark Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1
Rudjord-Levann, Asha M. ; Ye, Zilu ; Hafkenscheid, Lise ; Horn, Sabrina ; Wiegertjes, Renske ; Nielsen, Mathias A.I. ; Song, Ming ; Mathiesen, Caroline B.K. ; Stoop, Jesse and Stowell, Sean , et al. (2023) In iScience 26(7).
- Contribution to journal › Article
Mark Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds
Mahanti, Mukul ^LU ; Pal, Kumar Bhaskar ; Kumar, Rohit ^LU ; Schulze, Markus ; Leffler, Hakon ^LU ; Logan, Derek T ^LU and Nilsson, Ulf J ^LU (2023) In Journal of Medicinal Chemistry 66(21). p.14716-14723
- Contribution to journal › Article
Mark Discovery of Selective and Orally Available Galectin-1 Inhibitors
Zetterberg, Fredrik R ; Diehl, Carl ^LU ; Håkansson, Maria ^LU ; Kahl-Knutson, Barbro ^LU ; Leffler, Hakon ^LU ; Nilsson, Ulf J ^LU ; Peterson, Kristoffer ^LU ; Roper, James A and Slack, Robert J (2023) In Journal of Medicinal Chemistry 66(24). p.16980-16990
- Contribution to journal › Article

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