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- 2018
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Mark
Silencing of the FTO gene inhibits insulin secretion : An in vitro study using GRINCH cells
(
- Contribution to journal › Article
- 2015
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Mark
Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia.
(
- Contribution to journal › Article
- 2014
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Mark
A Central Role for GRB10 in Regulation of Islet Function in Man.
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- Contribution to journal › Article
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Mark
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
(
- Contribution to journal › Article
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Mark
Downregulation of Type II Diabetes Mellitus and Maturity Onset Diabetes of Young Pathways in Human Pancreatic Islets from Hyperglycemic Donors.
(
- Contribution to journal › Article
- 2013
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Mark
Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.
(
- Contribution to journal › Article
- 2012
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Mark
Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
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- Contribution to journal › Article
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Mark
Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.
(
- Contribution to journal › Article
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Mark
γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes.
(
- Contribution to journal › Article
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Mark
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
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- Contribution to journal › Article
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Mark
A common variant upstream of the PAX6 gene influences islet function in man.
(
- Contribution to journal › Article
- 2011
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Mark
Pleiotropic Effects of GIP on Islet Function Involve Osteopontin
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- Contribution to journal › Article
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Mark
Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
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- Contribution to journal › Article
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Mark
Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets.
(
- Contribution to journal › Article
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Mark
A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
(
- Contribution to journal › Article
- 2010
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Mark
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
(
- Contribution to journal › Article
- 2009
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Mark
The impact of differential splicing of TCF7L2 on target gene expression in human islet of Langerhans
2009) 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes In Diabetologia 52(Suppl 1). p.78-78(
- Contribution to journal › Published meeting abstract
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Mark
A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.
(
- Contribution to journal › Article
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Mark
Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion.
(
- Contribution to journal › Article