Inhibition of nuclear factor of activated T-cells (NFAT) suppresses accelerated atherosclerosis in diabetic mice.
Zetterqvist, Anna LU
; Berglund, Lisa
LU
; Blanco, Fabiana
LU
; Garcia Vaz, Eliana
LU
; Wigren, Maria
LU
; Dunér, Pontus
LU
; Dutius Andersson, Anna-Maria
LU
; To, Fong
LU
; Spégel, Peter
LU
and Nilsson, Jan
LU
, et al.
(2013)
In PLoS ONE
8(6).
- Abstract
- Diabetic patients have a much more widespread and aggressive form of atherosclerosis and therefore, higher risk for myocardial infarction, peripheral vascular disease and stroke, but the molecular mechanisms leading to accelerated damage are still unclear. Recently, we showed that hyperglycemia activates the transcription factor NFAT in the arterial wall, inducing the expression of the pro-atherosclerotic protein osteopontin. Here we investigate whether NFAT activation may be a link between diabetes and atherogenesis.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3913480
- author
- Zetterqvist, Anna
LU
; Berglund, Lisa
LU
; Blanco, Fabiana
LU
; Garcia Vaz, Eliana
LU
; Wigren, Maria
LU
; Dunér, Pontus
LU
; Dutius Andersson, Anna-Maria
LU
; To, Fong
LU
; Spégel, Peter
LU
and Nilsson, Jan
LU
, et al. (More)
- Zetterqvist, Anna
LU
; Berglund, Lisa
LU
; Blanco, Fabiana
LU
; Garcia Vaz, Eliana
LU
; Wigren, Maria
LU
; Dunér, Pontus
LU
; Dutius Andersson, Anna-Maria
LU
; To, Fong
LU
; Spégel, Peter
LU
; Nilsson, Jan
LU
; Bengtsson, Eva
LU
and Gomez, Maria
LU
(Less)
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS ONE
- volume
- 8
- issue
- 6
- article number
- e65020
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- wos:000319872300042
- pmid:23755169
- scopus:84878655746
- pmid:23755169
- ISSN
- 1932-6203
- DOI
- 10.1371/journal.pone.0065020
- language
- English
- LU publication?
- yes
- id
- b72bd34a-f17f-40ee-bc0a-1767c9a10e7d (old id 3913480)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23755169?dopt=Abstract
- date added to LUP
- 2016-04-01 13:36:50
- date last changed
- 2024-03-13 15:04:50
@article{b72bd34a-f17f-40ee-bc0a-1767c9a10e7d,
abstract = {{Diabetic patients have a much more widespread and aggressive form of atherosclerosis and therefore, higher risk for myocardial infarction, peripheral vascular disease and stroke, but the molecular mechanisms leading to accelerated damage are still unclear. Recently, we showed that hyperglycemia activates the transcription factor NFAT in the arterial wall, inducing the expression of the pro-atherosclerotic protein osteopontin. Here we investigate whether NFAT activation may be a link between diabetes and atherogenesis.}},
author = {{Zetterqvist, Anna and Berglund, Lisa and Blanco, Fabiana and Garcia Vaz, Eliana and Wigren, Maria and Dunér, Pontus and Dutius Andersson, Anna-Maria and To, Fong and Spégel, Peter and Nilsson, Jan and Bengtsson, Eva and Gomez, Maria}},
issn = {{1932-6203}},
language = {{eng}},
number = {{6}},
publisher = {{Public Library of Science (PLoS)}},
series = {{PLoS ONE}},
title = {{Inhibition of nuclear factor of activated T-cells (NFAT) suppresses accelerated atherosclerosis in diabetic mice.}},
url = {{https://lup.lub.lu.se/search/files/3477880/4114182.pdf}},
doi = {{10.1371/journal.pone.0065020}},
volume = {{8}},
year = {{2013}},
}