Serotonin (5-HT) receptor 2b activation augments glucose-stimulated insulin secretion in human and mouse islets of Langerhans.
(2016) In Diabetologia 59(4). p.744-754- Abstract
- The Gq-coupled 5-hydroxytryptamine 2B (5-HT2B) receptor is known to regulate the proliferation of islet beta cells during pregnancy. However, the role of serotonin in the control of insulin release is still controversial. The aim of the present study was to explore the role of the 5-HT2B receptor in the regulation of insulin secretion in mouse and human islets, as well as in clonal INS-1(832/13) cells.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8593036
- author
- Bennet, Hedvig
LU
; Mollet, Ines
LU
; Balhuizen, Alexander
LU
; Medina Benavente, Anya
LU
; Nagorny, Cecilia
LU
; Bagge, Annika
LU
; Fadista, Joao
LU
; Ottosson Laakso, Emilia
LU
; Vikman, Petter
LU
; Dekker Nitert, Marloes
LU
; Eliasson, Lena
LU
; Wierup, Nils
LU
; Artner, Isabella
LU
and Fex, Malin
LU
(Less) - organization
-
- Celiac Disease and Diabetes Unit (research group)
- Diabetes - Islet Cell Exocytosis (research group)
- Diabetes - Molecular Metabolism (research group)
- Translational Muscle Research (research group)
- Neuroendocrine Cell Biology (research group)
- Stem Cell Center
- EXODIAB: Excellence of Diabetes Research in Sweden
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
- publishing date
- 2016-01-06
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Diabetologia
- volume
- 59
- issue
- 4
- pages
- 744 - 754
- publisher
- Springer
- external identifiers
-
- pmid:26733006
- scopus:84959556025
- wos:000371802700013
- pmid:26733006
- ISSN
- 1432-0428
- DOI
- 10.1007/s00125-015-3847-6
- language
- English
- LU publication?
- yes
- id
- ca5cab25-bfd2-4c97-897f-70d1ed2d7448 (old id 8593036)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26733006?dopt=Abstract
- date added to LUP
- 2016-04-04 06:58:18
- date last changed
- 2024-03-29 14:26:45
@article{ca5cab25-bfd2-4c97-897f-70d1ed2d7448,
abstract = {{The Gq-coupled 5-hydroxytryptamine 2B (5-HT2B) receptor is known to regulate the proliferation of islet beta cells during pregnancy. However, the role of serotonin in the control of insulin release is still controversial. The aim of the present study was to explore the role of the 5-HT2B receptor in the regulation of insulin secretion in mouse and human islets, as well as in clonal INS-1(832/13) cells.}},
author = {{Bennet, Hedvig and Mollet, Ines and Balhuizen, Alexander and Medina Benavente, Anya and Nagorny, Cecilia and Bagge, Annika and Fadista, Joao and Ottosson Laakso, Emilia and Vikman, Petter and Dekker Nitert, Marloes and Eliasson, Lena and Wierup, Nils and Artner, Isabella and Fex, Malin}},
issn = {{1432-0428}},
language = {{eng}},
month = {{01}},
number = {{4}},
pages = {{744--754}},
publisher = {{Springer}},
series = {{Diabetologia}},
title = {{Serotonin (5-HT) receptor 2b activation augments glucose-stimulated insulin secretion in human and mouse islets of Langerhans.}},
url = {{http://dx.doi.org/10.1007/s00125-015-3847-6}},
doi = {{10.1007/s00125-015-3847-6}},
volume = {{59}},
year = {{2016}},
}