Combined Clinical and Radiological Prognostic Model in Acute Ischemic Stroke
Abul-Kasim, Kasim LU ; Brizzi, Marco LU ; Petersson, Jesper LU ; Buchwald, Fredrik LU and Sundgren, Pia LU
(2010)
In Acta Neurologica Belgica
110(3).
p.239-245
- Abstract
- We sought to propose and test the validity of a comprehensive prognostic model in middle cerebral artery-stroke treated with Intravenous thrombolysis. A total of 127 consecutive patients (aged 70 +/- 12 years; 54% males) were included in this retrospective study. Variables included in our prognostic model were: NIHSS on admission (1-3 points), occurrence of hyperdense middle cerebral artery sign and early ischemic signs on baseline CT (1 point each). NIHSS at 24 hours (0-3 points), posttreatment hemorrhage (1 point), and infarct volume (0-4 points). The score range teas 1-13, with higher values suggest unfavorable prognosis. Our prognostic score was correlated with the modified Rankin scale (mRS) at 3 months after stroke [correlation... (More)
- We sought to propose and test the validity of a comprehensive prognostic model in middle cerebral artery-stroke treated with Intravenous thrombolysis. A total of 127 consecutive patients (aged 70 +/- 12 years; 54% males) were included in this retrospective study. Variables included in our prognostic model were: NIHSS on admission (1-3 points), occurrence of hyperdense middle cerebral artery sign and early ischemic signs on baseline CT (1 point each). NIHSS at 24 hours (0-3 points), posttreatment hemorrhage (1 point), and infarct volume (0-4 points). The score range teas 1-13, with higher values suggest unfavorable prognosis. Our prognostic score was correlated with the modified Rankin scale (mRS) at 3 months after stroke [correlation coefficient of 0.62, P < 0.001] and can thus help early prediction of the functional outcome. Logistic regression showed that NIHSS at 24 hours and EICs on baseline CT were independent predictor of our prognostic score (adjusted odds ratio of 4.1 and 5). Adopting a cut-off value of prognostic score <= 3 for favorable prognosis and >= 7 for unfavorable prognosis helped to predict the need for institutionalization and the functional outcome with higher accuracy and predictive values compared with using scores only based on NIHSS. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1720203
- author
- Abul-Kasim, Kasim
LU
; Brizzi, Marco
LU
; Petersson, Jesper
LU
; Buchwald, Fredrik
LU
and Sundgren, Pia
LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- volume, infarct, computed tomography, acute ischemic stroke, prognostic score, favorable prognosis, cut-off values
- in
- Acta Neurologica Belgica
- volume
- 110
- issue
- 3
- pages
- 239 - 245
- publisher
- Springer
- external identifiers
-
- wos:000283706900005
- pmid:21114132
- scopus:79952113723
- ISSN
- 2240-2993
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Medical Radiology Unit (013241410), Neurology, Malmö (013027010), Diagnostic Radiology, (Lund) (013038000)
- id
- 1a135daa-feb0-4e6f-95ad-470f8c636f3c (old id 1720203)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/21114132?dopt=Abstract
- date added to LUP
- 2016-04-01 13:23:17
- date last changed
- 2022-01-27 18:57:33
@article{1a135daa-feb0-4e6f-95ad-470f8c636f3c,
abstract = {{We sought to propose and test the validity of a comprehensive prognostic model in middle cerebral artery-stroke treated with Intravenous thrombolysis. A total of 127 consecutive patients (aged 70 +/- 12 years; 54% males) were included in this retrospective study. Variables included in our prognostic model were: NIHSS on admission (1-3 points), occurrence of hyperdense middle cerebral artery sign and early ischemic signs on baseline CT (1 point each). NIHSS at 24 hours (0-3 points), posttreatment hemorrhage (1 point), and infarct volume (0-4 points). The score range teas 1-13, with higher values suggest unfavorable prognosis. Our prognostic score was correlated with the modified Rankin scale (mRS) at 3 months after stroke [correlation coefficient of 0.62, P < 0.001] and can thus help early prediction of the functional outcome. Logistic regression showed that NIHSS at 24 hours and EICs on baseline CT were independent predictor of our prognostic score (adjusted odds ratio of 4.1 and 5). Adopting a cut-off value of prognostic score <= 3 for favorable prognosis and >= 7 for unfavorable prognosis helped to predict the need for institutionalization and the functional outcome with higher accuracy and predictive values compared with using scores only based on NIHSS.}},
author = {{Abul-Kasim, Kasim and Brizzi, Marco and Petersson, Jesper and Buchwald, Fredrik and Sundgren, Pia}},
issn = {{2240-2993}},
keywords = {{volume; infarct; computed tomography; acute ischemic stroke; prognostic score; favorable prognosis; cut-off values}},
language = {{eng}},
number = {{3}},
pages = {{239--245}},
publisher = {{Springer}},
series = {{Acta Neurologica Belgica}},
title = {{Combined Clinical and Radiological Prognostic Model in Acute Ischemic Stroke}},
url = {{http://www.ncbi.nlm.nih.gov/pubmed/21114132?dopt=Abstract}},
volume = {{110}},
year = {{2010}},
}