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Low physical activity level in out-of-hospital cardiac arrest survivors with obesity, mobility problems and cognitive impairment : Results from the TTM2 trial

Heimburg, Katarina LU ; Blennow Nordström, Erik LU orcid ; Dankiewicz, Josef LU orcid ; Friberg, Hans LU ; Grejs, Anders M ; Haenggi, Mattias ; Keeble, Thomas R ; Kirkegaard, Hans ; Nielsen, Niklas LU and Rylander, Christian , et al. (2024) In Resuscitation 204.
Abstract

AIMS: To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.

METHODS: Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and New Zeeland were invited to a follow-up. The participants answered two questions on self-reported physical activity. Answers were categorized as a low, moderate, or high level of physical activity and further dichotomized into a low versus moderate/high level of physical activity. Potential risk factors for a low level of physical... (More)

AIMS: To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.

METHODS: Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and New Zeeland were invited to a follow-up. The participants answered two questions on self-reported physical activity. Answers were categorized as a low, moderate, or high level of physical activity and further dichotomized into a low versus moderate/high level of physical activity. Potential risk factors for a low level of physical activity were collected and investigated by univariable and multivariable logistic regression.

RESULTS: At 6 months, 807 of 939 (86%) OHCA survivors answered the two questions of physical activity; 34% reported a low, 44% moderate and 22% high level of physical activity. Obesity (OR=1.75, 95% CI 1.10-2.77, p=0.018), mobility problems by EuroQol 5 dimensions 5 levels (OR=1.73, 95% CI 1.06-2.84, p=0.029), and cognitive impairment by Symbol Digit Modalities Test (OR=1.78, 95% CI 1.13-2.82, p=0.013) were significantly associated with a low level of physical activity in the multivariable analysis.

CONCLUSION: One third of the OHCA survivors reported a low level of physical activity. Obesity, mobility problems, and cognitive impairment were associated with a low level of physical activity.

CLINICALTRIALS: gov Identifier: NCT02908308.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Resuscitation
volume
204
article number
110407
publisher
Elsevier
external identifiers
  • scopus:85206144627
  • pmid:39368797
ISSN
1873-1570
DOI
10.1016/j.resuscitation.2024.110407
language
English
LU publication?
yes
additional info
Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.
id
4625c498-db8b-4f28-bf59-3bae4b0c2fba
date added to LUP
2024-10-13 15:27:08
date last changed
2025-07-10 05:43:36
@article{4625c498-db8b-4f28-bf59-3bae4b0c2fba,
  abstract     = {{<p>AIMS: To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.</p><p>METHODS: Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and New Zeeland were invited to a follow-up. The participants answered two questions on self-reported physical activity. Answers were categorized as a low, moderate, or high level of physical activity and further dichotomized into a low versus moderate/high level of physical activity. Potential risk factors for a low level of physical activity were collected and investigated by univariable and multivariable logistic regression.</p><p>RESULTS: At 6 months, 807 of 939 (86%) OHCA survivors answered the two questions of physical activity; 34% reported a low, 44% moderate and 22% high level of physical activity. Obesity (OR=1.75, 95% CI 1.10-2.77, p=0.018), mobility problems by EuroQol 5 dimensions 5 levels (OR=1.73, 95% CI 1.06-2.84, p=0.029), and cognitive impairment by Symbol Digit Modalities Test (OR=1.78, 95% CI 1.13-2.82, p=0.013) were significantly associated with a low level of physical activity in the multivariable analysis.</p><p>CONCLUSION: One third of the OHCA survivors reported a low level of physical activity. Obesity, mobility problems, and cognitive impairment were associated with a low level of physical activity.</p><p>CLINICALTRIALS: gov Identifier: NCT02908308.</p>}},
  author       = {{Heimburg, Katarina and Blennow Nordström, Erik and Dankiewicz, Josef and Friberg, Hans and Grejs, Anders M and Haenggi, Mattias and Keeble, Thomas R and Kirkegaard, Hans and Nielsen, Niklas and Rylander, Christian and Tornberg, Åsa B and Ullén, Susann and Wise, Matthew P and Cronberg, Tobias and Lilja, Gisela}},
  issn         = {{1873-1570}},
  language     = {{eng}},
  month        = {{10}},
  publisher    = {{Elsevier}},
  series       = {{Resuscitation}},
  title        = {{Low physical activity level in out-of-hospital cardiac arrest survivors with obesity, mobility problems and cognitive impairment : Results from the TTM2 trial}},
  url          = {{http://dx.doi.org/10.1016/j.resuscitation.2024.110407}},
  doi          = {{10.1016/j.resuscitation.2024.110407}},
  volume       = {{204}},
  year         = {{2024}},
}