Intraneural edema following exposure to vibration
(1987) In Scandinavian Journal of Work, Environment and Health 13(4). p.9-326- Abstract
Peripheral neuropathy represents a well-known complication from long-term exposure to vibration. In the present study an experimental model is presented with the purpose of analyzing the formation of intraneural edema following vibration exposure. Vibration (82 Hz, peak-to-peak amplitude 0.21 mm) was induced in the hind limb of rats by the use of vibrating electric motors during 4 h/d for 5 d. Tracer techniques (with albumin Evans blue and horseradish peroxidase) were used to study the permeability of intraneural microvessels after the vibration exposure on day 5. It was found that the vibration trauma in this model induced epineurial edema in the sciatic nerve. It is hypothesized that the formation of intraneural edema may be an... (More)
Peripheral neuropathy represents a well-known complication from long-term exposure to vibration. In the present study an experimental model is presented with the purpose of analyzing the formation of intraneural edema following vibration exposure. Vibration (82 Hz, peak-to-peak amplitude 0.21 mm) was induced in the hind limb of rats by the use of vibrating electric motors during 4 h/d for 5 d. Tracer techniques (with albumin Evans blue and horseradish peroxidase) were used to study the permeability of intraneural microvessels after the vibration exposure on day 5. It was found that the vibration trauma in this model induced epineurial edema in the sciatic nerve. It is hypothesized that the formation of intraneural edema may be an important pathophysiological factor in the occurrence of vibration-induced neuropathy.
(Less)
- author
- Lundborg, G LU ; Dahlin, L B LU ; Danielsen, N LU ; Hansson, H A ; Necking, L E LU and Pyykkö, I.
- organization
- publishing date
- 1987-08
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Animals, Edema, Horseradish Peroxidase, Rats, Rats, Inbred Strains, Sciatic Nerve, Vascular Diseases, Vibration, Journal Article, Research Support, Non-U.S. Gov't
- in
- Scandinavian Journal of Work, Environment and Health
- volume
- 13
- issue
- 4
- pages
- 4 pages
- publisher
- Finnish Institute of Occupational Health
- external identifiers
-
- scopus:0023226713
- pmid:3433033
- ISSN
- 0355-3140
- language
- English
- LU publication?
- yes
- id
- 764d435e-0aa6-4c98-8b33-71fa07e41872
- date added to LUP
- 2017-10-13 14:07:31
- date last changed
- 2024-01-14 07:25:06
@article{764d435e-0aa6-4c98-8b33-71fa07e41872, abstract = {{<p>Peripheral neuropathy represents a well-known complication from long-term exposure to vibration. In the present study an experimental model is presented with the purpose of analyzing the formation of intraneural edema following vibration exposure. Vibration (82 Hz, peak-to-peak amplitude 0.21 mm) was induced in the hind limb of rats by the use of vibrating electric motors during 4 h/d for 5 d. Tracer techniques (with albumin Evans blue and horseradish peroxidase) were used to study the permeability of intraneural microvessels after the vibration exposure on day 5. It was found that the vibration trauma in this model induced epineurial edema in the sciatic nerve. It is hypothesized that the formation of intraneural edema may be an important pathophysiological factor in the occurrence of vibration-induced neuropathy.</p>}}, author = {{Lundborg, G and Dahlin, L B and Danielsen, N and Hansson, H A and Necking, L E and Pyykkö, I.}}, issn = {{0355-3140}}, keywords = {{Animals; Edema; Horseradish Peroxidase; Rats; Rats, Inbred Strains; Sciatic Nerve; Vascular Diseases; Vibration; Journal Article; Research Support, Non-U.S. Gov't}}, language = {{eng}}, number = {{4}}, pages = {{9--326}}, publisher = {{Finnish Institute of Occupational Health}}, series = {{Scandinavian Journal of Work, Environment and Health}}, title = {{Intraneural edema following exposure to vibration}}, volume = {{13}}, year = {{1987}}, }