A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients.
(2018) European Congress on Emergency Medicine- Abstract
- Background
In emergency department (ED) chest pain patients, the European Society of Cardiology recommends the use of a 0h/1h high-sensitivity cardiac Troponin (hs-cTn) protocol. However, the recommendation is based on observational studies and the effects of the protocol when implemented in routine care is unknown. The aim of this study is to determine the safety and effectiveness of the ESC 0h/1h hs-cTnT protocol, supplemented with clinical assessment and ECG, when implemented in routine care
Methods
In this before-and-after implementation study with concurrent controls, all patients ≥18 years with a chief complaint of non-traumatic chest pain and possible acute coronary syndrome (ACS) will be included at the EDs of... (More) - Background
In emergency department (ED) chest pain patients, the European Society of Cardiology recommends the use of a 0h/1h high-sensitivity cardiac Troponin (hs-cTn) protocol. However, the recommendation is based on observational studies and the effects of the protocol when implemented in routine care is unknown. The aim of this study is to determine the safety and effectiveness of the ESC 0h/1h hs-cTnT protocol, supplemented with clinical assessment and ECG, when implemented in routine care
Methods
In this before-and-after implementation study with concurrent controls, all patients ≥18 years with a chief complaint of non-traumatic chest pain and possible acute coronary syndrome (ACS) will be included at the EDs of Skåne University Hospital at Lund and Malmö, Helsingborg Hospital, Ystad Hospital and Kristianstad Hospital in southern Sweden. Patients with STEMI, patients leaving against medical advice and non-Swedish residents will be excluded. The 0h/1h protocol identifies low-risk patients suitable for early discharge home, high-risk patients suitable for immediate hospital admission, and intermediate risk patients suitable for further diagnostic assessment. The protocol will be implemented at the Lund, Helsingborg and Ystad EDs but not at the Malmö and Kristianstad EDs which will be concurrent controls. Patient outcomes will be compared in the 10-month periods before and after the implementation (starting February 1, 2018) both at the protocol-implementing and control hospitals. The primary outcomes are the 30-day rate of acute myocardial infarction/all-cause death and the ED length of stay (LOS) in patients discharged from the ED. Secondary outcomes include the proportion of patients discharged from the ED and of non-ACS-patients admitted to the cardiac care unit, further cardiac testing within 30 days and health care costs.
Results
No results are available at this time (April 23, 2018). The main results of the study will be presented in 2019.
Conclusion
If a 0h/1h protocol implemented in routine care can rapidly identify a large proportion of chest pain patients suitable for early discharge with no need for further cardiac testing, this may reduce ED and hospital crowding, objective testing, health care costs and will benefit both patients and the health care system. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/9345a4eb-b669-44fe-94af-681bf6eaccb3
- author
- Mokhtari, Arash LU ; Lundager Forberg, Jakob LU ; af Segerstad, Caroline Hård ; Akbarzadeh Mameghanilar, Mahin LU ; Khoshnood, Ardavan LU and Ekelund, Ulf LU
- organization
- publishing date
- 2018
- type
- Contribution to conference
- publication status
- published
- subject
- keywords
- Troponin, Acute Coronary Syndrome, Troponon, Akut Koronart Syndrom
- conference name
- European Congress on Emergency Medicine
- conference location
- Glasgow, United Kingdom
- conference dates
- 2018-09-08 - 2018-09-12
- language
- English
- LU publication?
- yes
- id
- 9345a4eb-b669-44fe-94af-681bf6eaccb3
- date added to LUP
- 2018-09-09 00:16:38
- date last changed
- 2023-06-06 00:26:28
@misc{9345a4eb-b669-44fe-94af-681bf6eaccb3, abstract = {{Background<br/>In emergency department (ED) chest pain patients, the European Society of Cardiology recommends the use of a 0h/1h high-sensitivity cardiac Troponin (hs-cTn) protocol. However, the recommendation is based on observational studies and the effects of the protocol when implemented in routine care is unknown. The aim of this study is to determine the safety and effectiveness of the ESC 0h/1h hs-cTnT protocol, supplemented with clinical assessment and ECG, when implemented in routine care<br/><br/>Methods<br/>In this before-and-after implementation study with concurrent controls, all patients ≥18 years with a chief complaint of non-traumatic chest pain and possible acute coronary syndrome (ACS) will be included at the EDs of Skåne University Hospital at Lund and Malmö, Helsingborg Hospital, Ystad Hospital and Kristianstad Hospital in southern Sweden. Patients with STEMI, patients leaving against medical advice and non-Swedish residents will be excluded. The 0h/1h protocol identifies low-risk patients suitable for early discharge home, high-risk patients suitable for immediate hospital admission, and intermediate risk patients suitable for further diagnostic assessment. The protocol will be implemented at the Lund, Helsingborg and Ystad EDs but not at the Malmö and Kristianstad EDs which will be concurrent controls. Patient outcomes will be compared in the 10-month periods before and after the implementation (starting February 1, 2018) both at the protocol-implementing and control hospitals. The primary outcomes are the 30-day rate of acute myocardial infarction/all-cause death and the ED length of stay (LOS) in patients discharged from the ED. Secondary outcomes include the proportion of patients discharged from the ED and of non-ACS-patients admitted to the cardiac care unit, further cardiac testing within 30 days and health care costs.<br/><br/>Results<br/>No results are available at this time (April 23, 2018). The main results of the study will be presented in 2019. <br/><br/>Conclusion<br/>If a 0h/1h protocol implemented in routine care can rapidly identify a large proportion of chest pain patients suitable for early discharge with no need for further cardiac testing, this may reduce ED and hospital crowding, objective testing, health care costs and will benefit both patients and the health care system.}}, author = {{Mokhtari, Arash and Lundager Forberg, Jakob and af Segerstad, Caroline Hård and Akbarzadeh Mameghanilar, Mahin and Khoshnood, Ardavan and Ekelund, Ulf}}, keywords = {{Troponin; Acute Coronary Syndrome; Troponon; Akut Koronart Syndrom}}, language = {{eng}}, title = {{A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients.}}, year = {{2018}}, }