Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Cohort profile : The Obesity and Disease Development Sweden (ODDS) study, a pooled cohort

da Silva, Marisa LU orcid ; Fritz, Josef LU ; Mboya, Innocent B LU orcid ; Sun, Ming LU ; Wahlström, Jens LU orcid ; van Guelpen, Bethany ; Michaëlsson, Karl ; Magnusson, Patrik K E ; Melander, Olle LU orcid and Sandin, Sven , et al. (2024) In BMJ Open 14(7).
Abstract

PURPOSE: The Obesity and Disease Development Sweden (ODDS) study was designed to create a large cohort to study body mass index (BMI), waist circumference (WC) and changes in weight and WC, in relation to morbidity and mortality.

PARTICIPANTS: ODDS includes 4 295 859 individuals, 2 165 048 men and 2 130 811 women, in Swedish cohorts and national registers with information on weight assessed once (2 555 098 individuals) or more (1 740 761 individuals), in total constituting 7 733 901 weight assessments at the age of 17-103 years in 1963-2020 (recalled weight as of 1911). Information on WC is available in 152 089 men and 212 658 women, out of whom 108 795 have repeated information on WC (in total 512 273 assessments). Information on... (More)

PURPOSE: The Obesity and Disease Development Sweden (ODDS) study was designed to create a large cohort to study body mass index (BMI), waist circumference (WC) and changes in weight and WC, in relation to morbidity and mortality.

PARTICIPANTS: ODDS includes 4 295 859 individuals, 2 165 048 men and 2 130 811 women, in Swedish cohorts and national registers with information on weight assessed once (2 555 098 individuals) or more (1 740 761 individuals), in total constituting 7 733 901 weight assessments at the age of 17-103 years in 1963-2020 (recalled weight as of 1911). Information on WC is available in 152 089 men and 212 658 women, out of whom 108 795 have repeated information on WC (in total 512 273 assessments). Information on morbidity and mortality was retrieved from national registers, with follow-up until the end of 2019-2021, varying between the registers.

FINDINGS TO DATE: Among all weight assessments (of which 85% are objectively measured), the median year, age and BMI (IQR) is 1985 (1977-1994) in men and 2001 (1991-2010) in women, age 19 (18-40) years in men and 30 (26-36) years in women and BMI 22.9 (20.9-25.4) kg/m
2 in men and 23.2 (21.2-26.1) kg/m
2 in women. Normal weight (BMI 18.5-24.9 kg/m
2) is present in 67% of assessments in men and 64% in women and obesity (BMI≥30 kg/m
2) in 5% of assessments in men and 10% in women. The median (IQR) follow-up time from the first objectively measured or self-reported current weight assessment until emigration, death or end of follow-up is 31.4 (21.8-40.8) years in men and 19.6 (9.3-29.0) years in women. During follow-up, 283 244 men and 123 457 women died.

FUTURE PLANS: The large sample size and long follow-up of the ODDS Study will provide robust results on anthropometric measures in relation to risk of common diseases and causes of deaths, and novel findings in subgroups and rarer outcomes.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and , et al. (More)
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; and (Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Humans, Sweden/epidemiology, Female, Male, Adult, Body Mass Index, Obesity/epidemiology, Middle Aged, Adolescent, Young Adult, Aged, Waist Circumference, Aged, 80 and over, Cohort Studies, Registries
in
BMJ Open
volume
14
issue
7
article number
e084836
publisher
BMJ Publishing Group
external identifiers
  • pmid:39013647
ISSN
2044-6055
DOI
10.1136/bmjopen-2024-084836
language
English
LU publication?
yes
additional info
© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
id
b87d6540-4719-4e25-bf5b-81d9eea9b4f8
date added to LUP
2024-07-23 13:08:36
date last changed
2024-07-24 08:18:36
@article{b87d6540-4719-4e25-bf5b-81d9eea9b4f8,
  abstract     = {{<p>PURPOSE: The Obesity and Disease Development Sweden (ODDS) study was designed to create a large cohort to study body mass index (BMI), waist circumference (WC) and changes in weight and WC, in relation to morbidity and mortality.</p><p>PARTICIPANTS: ODDS includes 4 295 859 individuals, 2 165 048 men and 2 130 811 women, in Swedish cohorts and national registers with information on weight assessed once (2 555 098 individuals) or more (1 740 761 individuals), in total constituting 7 733 901 weight assessments at the age of 17-103 years in 1963-2020 (recalled weight as of 1911). Information on WC is available in 152 089 men and 212 658 women, out of whom 108 795 have repeated information on WC (in total 512 273 assessments). Information on morbidity and mortality was retrieved from national registers, with follow-up until the end of 2019-2021, varying between the registers.</p><p>FINDINGS TO DATE: Among all weight assessments (of which 85% are objectively measured), the median year, age and BMI (IQR) is 1985 (1977-1994) in men and 2001 (1991-2010) in women, age 19 (18-40) years in men and 30 (26-36) years in women and BMI 22.9 (20.9-25.4) kg/m<br>
 2 in men and 23.2 (21.2-26.1) kg/m<br>
 2 in women. Normal weight (BMI 18.5-24.9 kg/m<br>
 2) is present in 67% of assessments in men and 64% in women and obesity (BMI≥30 kg/m<br>
 2) in 5% of assessments in men and 10% in women. The median (IQR) follow-up time from the first objectively measured or self-reported current weight assessment until emigration, death or end of follow-up is 31.4 (21.8-40.8) years in men and 19.6 (9.3-29.0) years in women. During follow-up, 283 244 men and 123 457 women died.<br>
 </p><p>FUTURE PLANS: The large sample size and long follow-up of the ODDS Study will provide robust results on anthropometric measures in relation to risk of common diseases and causes of deaths, and novel findings in subgroups and rarer outcomes.</p>}},
  author       = {{da Silva, Marisa and Fritz, Josef and Mboya, Innocent B and Sun, Ming and Wahlström, Jens and van Guelpen, Bethany and Michaëlsson, Karl and Magnusson, Patrik K E and Melander, Olle and Sandin, Sven and Yin, Weiyao and Trolle Lagerros, Ylva and Nwaru, Bright and Leppert, Jerzy and Chabok, Abbas and Pedersen, Nancy L and Elmståhl, Sölve and Isaksson, Karolin and Ingvar, Christian and Hedman, Linnea and Backman, Helena and Häggström, Christel and Stocks, Tanja}},
  issn         = {{2044-6055}},
  keywords     = {{Humans; Sweden/epidemiology; Female; Male; Adult; Body Mass Index; Obesity/epidemiology; Middle Aged; Adolescent; Young Adult; Aged; Waist Circumference; Aged, 80 and over; Cohort Studies; Registries}},
  language     = {{eng}},
  month        = {{07}},
  number       = {{7}},
  publisher    = {{BMJ Publishing Group}},
  series       = {{BMJ Open}},
  title        = {{Cohort profile : The Obesity and Disease Development Sweden (ODDS) study, a pooled cohort}},
  url          = {{http://dx.doi.org/10.1136/bmjopen-2024-084836}},
  doi          = {{10.1136/bmjopen-2024-084836}},
  volume       = {{14}},
  year         = {{2024}},
}