Blood transfusion at delivery and risk of subsequent malignant lymphoma in the mother
Anderson, H LU ; Brandt, L LU ; Ericson, A ; Olsson, Håkan LU
and Möller, Torgil
LU
(1998)
In Vox Sanguinis
75(2).
p.145-148
- Abstract
BACKGROUND AND OBJECTIVES: Blood transfusion has been shown to be a risk factor for non-Hodgkin's lymphoma (NHL).
MATERIALS AND METHODS: In a cohort of 77,928 women with bleeding complications at delivery in the period of 1973-1986, subsequent NHL cases were identified and the number was compared with the number expected from national incidence rates. In a case-control study the proportion of transfused NHL cases was compared with the proportion of transfused controls.
RESULTS: The observed number of NHL in the cohort was 18 versus 22.0 expected. Information on transfusion was obtained for 15 of the NHL cases and none (0%) was transfused versus 32 out of 136 controls (23%).
CONCLUSIONS: Blood transfusion at delivery is... (More)
BACKGROUND AND OBJECTIVES: Blood transfusion has been shown to be a risk factor for non-Hodgkin's lymphoma (NHL).
MATERIALS AND METHODS: In a cohort of 77,928 women with bleeding complications at delivery in the period of 1973-1986, subsequent NHL cases were identified and the number was compared with the number expected from national incidence rates. In a case-control study the proportion of transfused NHL cases was compared with the proportion of transfused controls.
RESULTS: The observed number of NHL in the cohort was 18 versus 22.0 expected. Information on transfusion was obtained for 15 of the NHL cases and none (0%) was transfused versus 32 out of 136 controls (23%).
CONCLUSIONS: Blood transfusion at delivery is not a risk factor for NHL. The immune tolerance induced by pregnancy may reduce the risk of NHL associated with the transfusion of allogeneic blood cells.
(Less)
- author
- Anderson, H
LU
; Brandt, L
LU
; Ericson, A
; Olsson, Håkan
LU
and Möller, Torgil
LU
- organization
- publishing date
- 1998
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Adult, Blood Transfusion, Case-Control Studies, Cohort Studies, Delivery, Obstetric, Female, Hodgkin Disease, Humans, Incidence, Lymphoma, Non-Hodgkin, Postpartum Hemorrhage, Pregnancy, Risk Factors, Sweden
- in
- Vox Sanguinis
- volume
- 75
- issue
- 2
- pages
- 145 - 148
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:0031721127
- pmid:9784669
- ISSN
- 0042-9007
- language
- English
- LU publication?
- yes
- id
- cbb74510-c64f-437f-a9fe-45882354d6fb
- date added to LUP
- 2016-09-18 12:35:27
- date last changed
- 2025-10-14 13:29:34
@article{cbb74510-c64f-437f-a9fe-45882354d6fb,
abstract = {{<p>BACKGROUND AND OBJECTIVES: Blood transfusion has been shown to be a risk factor for non-Hodgkin's lymphoma (NHL).</p><p>MATERIALS AND METHODS: In a cohort of 77,928 women with bleeding complications at delivery in the period of 1973-1986, subsequent NHL cases were identified and the number was compared with the number expected from national incidence rates. In a case-control study the proportion of transfused NHL cases was compared with the proportion of transfused controls.</p><p>RESULTS: The observed number of NHL in the cohort was 18 versus 22.0 expected. Information on transfusion was obtained for 15 of the NHL cases and none (0%) was transfused versus 32 out of 136 controls (23%).</p><p>CONCLUSIONS: Blood transfusion at delivery is not a risk factor for NHL. The immune tolerance induced by pregnancy may reduce the risk of NHL associated with the transfusion of allogeneic blood cells.</p>}},
author = {{Anderson, H and Brandt, L and Ericson, A and Olsson, Håkan and Möller, Torgil}},
issn = {{0042-9007}},
keywords = {{Adult; Blood Transfusion; Case-Control Studies; Cohort Studies; Delivery, Obstetric; Female; Hodgkin Disease; Humans; Incidence; Lymphoma, Non-Hodgkin; Postpartum Hemorrhage; Pregnancy; Risk Factors; Sweden}},
language = {{eng}},
number = {{2}},
pages = {{145--148}},
publisher = {{Wiley-Blackwell}},
series = {{Vox Sanguinis}},
title = {{Blood transfusion at delivery and risk of subsequent malignant lymphoma in the mother}},
volume = {{75}},
year = {{1998}},
}