Hakon Leffler

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2024
Mark Endocytic Roles of Glycans on Proteins and Lipids
Johannes, Ludger ; Shafaq-Zadah, Massiullah ; Dransart, Estelle ; Wunder, Christian and Leffler, Hakon ^LU (2024) In Cold Spring Harbor perspectives in biology 16(1).
- Contribution to journal › Article
Mark Determining the Affinity and Kinetics of Small Molecule Inhibitors of Galectin-1 Using Surface Plasmon Resonance
Kim, Henry ; Kretz, Louis ; Ronin, Céline ; Starck, Christina ; Roper, James A. ; Kahl-Knutson, Barbro ^LU ; Peterson, Kristoffer ^LU ; Leffler, Hakon ^LU ; Nilsson, Ulf J. ^LU and Pedersen, Anders , et al. (2024) In International Journal of Molecular Sciences 25(12).
- Contribution to journal › Article
Mark Galectin-8N-Selective 4-Halophenylphthalazinone-Galactals Double π-Stack in a Unique Pocket
van Klaveren, Sjors ^LU ; Hassan, Mujtaba ^LU ; Håkansson, Maria ^LU ; Johnsson, Richard E. ^LU ; Larsson, Jessica ^LU ; Jakopin, Žiga ; Anderluh, Marko ^LU ; Leffler, Hakon ^LU ; Tomašič, Tihomir and Nilsson, Ulf J. ^LU (2024) In ACS Medicinal Chemistry Letters 15(8). p.1319-1324
- Contribution to journal › Article
Mark Development and Characterization of a High-Affinity Selective Galectin-3 Mouse Tool Compound in Mouse Models of Cancer
Peterson, Kristoffer ^LU ; Nilsson, Ulf J. ^LU ; Gravelle, Lise ; Holyer, Ian ; Jansson, Karl ; Kahl-Knutson, Barbro ^LU ; Leffler, Hakon ^LU ; MacKinnon, Alison C. ; Roper, James A. and Slack, Robert J. , et al. (2024) In Journal of Medicinal Chemistry 67(24). p.21905-21915
- Contribution to journal › Article
Mark Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer
Zetterberg, Fredrik R. ; Peterson, Kristoffer ; Nilsson, Ulf J. ^LU ; Andréasson Dahlgren, Kajsa ; Diehl, Carl ; Hoyler, Ian ; Håkansson, Maria ; Khabut, Areej ^LU ; Kahl-Knutson, Barbro ^LU and Leffler, Hakon ^LU , et al. (2024) In Journal of Medicinal Chemistry 67(11). p.9374-9388
- Contribution to journal › Article
Mark The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis
Comeglio, Paolo ; Guarnieri, Giulia ; Filippi, Sandra ; Cellai, Ilaria ; Acciai, Gabriele ; Holyer, Ian ; Zetterberg, Fredrik ; Leffler, Hakon ^LU ; Kahl-Knutson, Barbro ^LU and Sarchielli, Erica , et al. (2024) In Frontiers in Pharmacology 15.
- Contribution to journal › Article
Mark Exploration into Galectin-3 Driven Endocytosis and Lattices
Shafaq-Zadah, Massiullah ; Dransart, Estelle ; Mani, Satish Kailasam ; Sampaio, Julio Lopes ; Bouidghaghen, Lydia ; Nilsson, Ulf J. ^LU ; Leffler, Hakon ^LU and Johannes, Ludger (2024) In Biomolecules 14(9).
- Contribution to journal › Article
2023
Mark Increased synovial galectin-3 induce inflammatory fibroblast activation and osteoclastogenesis in patients with rheumatoid arthritis
Nielsen, M. A. ; Køster, D. ; Greisen, S. ; Troldborg, A. ; Stengaard-Pedersen, K. ; Junker, P. ; Hørslev-Petersen, K. ; Hetland, M. L. ; Østergaard, M. and Hvid, M. , et al. (2023) In Scandinavian Journal of Rheumatology 52(1). p.33-41
- Contribution to journal › Article
Mark Discovery of Selective and Orally Available Galectin-1 Inhibitors
Zetterberg, Fredrik R ; Diehl, Carl ^LU ; Håkansson, Maria ^LU ; Kahl-Knutson, Barbro ^LU ; Leffler, Hakon ^LU ; Nilsson, Ulf J ^LU ; Peterson, Kristoffer ^LU ; Roper, James A and Slack, Robert J (2023) In Journal of Medicinal Chemistry 66(24). p.16980-16990
- Contribution to journal › Article
Mark Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1
Rudjord-Levann, Asha M. ; Ye, Zilu ; Hafkenscheid, Lise ; Horn, Sabrina ; Wiegertjes, Renske ; Nielsen, Mathias A.I. ; Song, Ming ; Mathiesen, Caroline B.K. ; Stoop, Jesse and Stowell, Sean , et al. (2023) In iScience 26(7).
- Contribution to journal › Article

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